NFL Odds, Picks for Every Game: Week 3 NFL Schedule

NFL Odds, Picks for Every Game: Week 3 NFL Schedule article feature image
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Getty Images. Pictured: NFL logo at 50-yard line.

Our experts have taken a look up and down the NFL Week 3 schedule and odds for every game, and they've come away with their best bets.

The tightest spread as of Sunday morning is in Ravens vs. Cowboys, where the Ravens are just 1-point favorites (-1). The biggest spread is in Commanders vs. Bengals on Monday Night Football, as Cincinnati is a 7.5-point favorite (-7.5). That means every game on Sunday is expected to be within 7 points, although 4 games have spreads of -6 or -6.5 today. The highest over/under is in Lions vs. Cardinals at 51.5 points, and the lowest total is the over/under 35 in Chargers vs. Steelers — one of 6 games with a total of 41 or lower.

But those are just the superlatives. Let's get to the Week 3 NFL odds, our expert picks, and NFL predictions for every game.

NFL Picks Sunday

NFL Odds Week 3

  • Eagles vs. Saints spread: Saints -2.5
  • Bears vs. Colts spread: Colts -1.5
  • Chargers vs. Steelers spread: Steelers -2.5
  • Texans vs. Vikings spread: Texans -1.5
  • Packers vs. Titans spread: Titans -3
  • Giants vs. Browns spread: Browns -6.5
  • Broncos vs. Buccaneers spread: Bucs -6.5
  • Ravens vs. Cowboys spread: Ravens -1
  • 49ers vs. Rams spread: 49ers -6.5
  • Lions vs. Cardinals spread: Lions -3
  • Panthers vs. Raiders spread: Raiders -6
  • Dolphins vs. Seahawks spread: Seahawks -4.5
  • Chiefs vs. Falcons spread: Chiefs -3
  • Jaguars vs. Bills spread: Bills -5
  • Commanders vs. Bengals spread: Bengals -7.5

NFL Schedule Week 3

Philadelphia Eagles at New Orleans Saints

Eagles Logo
Sunday, Sep 22
1 p.m. ET
FOX
Saints Logo
Eagles Odds
SpreadTotalMoneyline
+3
-120
49.5
-108o / -112u
+124
Saints Odds
SpreadTotalMoneyline
-3
+100
49.5
-108o / -112u
-148
Odds via DraftKings. Get up-to-the-minute NFL odds here.
DraftKings Logo
  • Eagles vs. Saints spread: Saints -3
  • Eagles vs. Saints over/under: 49.5 points
  • Eagles vs. Saints moneyline: Saints -150, Eagles +125
  • Eagles vs. Saints pick, prediction: Eagles to cover the spread

Chicago Bears at Indianapolis Colts

Bears Logo
Sunday, Sep 22
1 p.m. ET
CBS
Colts Logo
Bears Odds
SpreadTotalMoneyline
+1
-108
44
-105o / -115u
+100
Colts Odds
SpreadTotalMoneyline
-1
-112
44
-105o / -115u
-120
Odds via DraftKings. Get up-to-the-minute NFL odds here.
DraftKings Logo
  • Bears vs. Colts spread: Colts -1.5
  • Bears vs. Colts over/under: 43.5 points
  • Bears vs. Colts moneyline: Colts -120, Bears +100
  • Bears vs. Colts pick, prediction: Under the total

Los Angeles Chargers at Pittsburgh Steelers

Chargers Logo
Sunday, Sep 22
1 p.m. ET
CBS
Steelers Logo
Chargers Odds
SpreadTotalMoneyline
+2.5
-108
34.5
-112o / -108u
+120
Steelers Odds
SpreadTotalMoneyline
-2.5
-112
34.5
-112o / -108u
-142
Odds via DraftKings. Get up-to-the-minute NFL odds here.
DraftKings Logo
  • Chargers vs. Steelers spread: Steelers -2.5
  • Chargers vs. Steelers over/under: 35 points
  • Chargers vs. Steelers moneyline: Steelers -145, Chargers +120
  • Chargers vs. Steelers pick, prediction: Under the total

Houston Texans at Minnesota Vikings

Texans Logo
Sunday, Sep 22
1 p.m. ET
CBS
Vikings Logo
Texans Odds
SpreadTotalMoneyline
-1.5
-112
46
-112o / -108u
-125
Vikings Odds
SpreadTotalMoneyline
+1.5
-108
46
-112o / -108u
+105
Odds via DraftKings. Get up-to-the-minute NFL odds here.
DraftKings Logo
  • Texans vs. Vikings spread: Texans -1.5
  • Texans vs. Vikings over/under:  46 points
  • Texans vs. Vikings moneyline: Texans -125, Vikings +105
  • Texans vs. Vikings pick, prediction: Vikings to cover the spread

Green Bay Packers at Tennessee Titans

Packers Logo
Sunday, Sep 22
1 p.m. ET
FOX
Titans Logo
Packers Odds
SpreadTotalMoneyline
+3
-118
37.5
-108o / -112u
+130
Titans Odds
SpreadTotalMoneyline
-3
-102
37.5
-108o / -112u
-155
Odds via DraftKings. Get up-to-the-minute NFL odds here.
DraftKings Logo
  • Packers vs. Titans spread: Titans -3
  • Packers vs. Titans over/under: 37.5 points
  • Packers vs. Titans moneyline: Titans -155, Packers +130
  • Packers vs. Titans pick, prediction: Titans to cover the spread

New York Giants at Cleveland Browns

Giants Logo
Sunday, Sep 22
1 p.m. ET
FOX
Browns Logo
Giants Odds
SpreadTotalMoneyline
+6.5
-110
38
-112o / -108u
+225
Browns Odds
SpreadTotalMoneyline
-6.5
-110
38
-112o / -108u
-278
Odds via DraftKings. Get up-to-the-minute NFL odds here.
DraftKings Logo
  • Giants vs. Browns spread: Browns -6.5
  • Giants vs. Browns over/under: 38.5 points
  • Giants vs. Browns moneyline: Browns -300, Giants +240
  • Giants vs. Browns pick, prediction: Giants to cover the spread; Under the total

Denver Broncos at Tampa Bay Buccaneers

Broncos Logo
Sunday, Sep 22
1 p.m. ET
FOX
Buccaneers Logo
Broncos Odds
SpreadTotalMoneyline
+6
-110
41
-110o / -110u
+210
Buccaneers Odds
SpreadTotalMoneyline
-6
-110
41
-110o / -110u
-258
Odds via DraftKings. Get up-to-the-minute NFL odds here.
DraftKings Logo
  • Broncos vs. Buccaneers spread: Bucs -6
  • Broncos vs. Buccaneers over/under: 41 points
  • Broncos vs. Buccaneers moneyline: Bucs -275, Broncos +220
  • Broncos vs. Buccaneers pick, prediction: Broncos to cover the spread

Baltimore Ravens at Dallas Cowboys

Ravens Logo
Sunday, Sep 22
4:25 p.m. ET
FOX
Cowboys Logo
Ravens Odds
SpreadTotalMoneyline
-1
-110
47.5
-110o / -110u
-115
Cowboys Odds
SpreadTotalMoneyline
+1
-110
47.5
-110o / -110u
-105
Odds via DraftKings. Get up-to-the-minute NFL odds here.
DraftKings Logo
  • Ravens vs. Cowboys spread: Ravens -1
  • Ravens vs. Cowboys over/under: 47.5 points
  • Ravens vs. Cowboys moneyline: Ravens -115, Cowboys -105
  • Ravens vs. Cowboys pick, prediction: Ravens moneyline

San Francisco 49ers at Los Angeles Rams

49ers Logo
Sunday, Sep 22
4:25 p.m. ET
FOX
Rams Logo
49ers Odds
SpreadTotalMoneyline
-6.5
-108
43.5
-108o / -112u
-285
Rams Odds
SpreadTotalMoneyline
+6.5
-112
43.5
-108o / -112u
+230
Odds via DraftKings. Get up-to-the-minute NFL odds here.
DraftKings Logo
  • 49ers vs. Rams spread: 49ers -6.5
  • 49ers vs. Rams over/under: 43.5 points
  • 49ers vs. Rams moneyline: 49ers -295, Rams +235
  • 49ers vs. Rams pick, prediction: 49ers over

Detroit Lions at Arizona Cardinals

Lions Logo
Sunday, Sep 22
4:25 p.m. ET
FOX
Cardinals Logo
Lions Odds
SpreadTotalMoneyline
-3
-110
51.5
-110o / -110u
-155
Cardinals Odds
SpreadTotalMoneyline
+3
-110
51.5
-110o / -110u
+130
Odds via DraftKings. Get up-to-the-minute NFL odds here.
DraftKings Logo
  • Lions vs. Cardinals spread: Lions -3
  • Lions vs. Cardinals over/under: 51.5 points
  • Lions vs. Cardinals moneyline: Lions -150, Cardinals +125
  • Lions vs. Cardinals pick, prediction: Lions to cover the spread

Carolina Panthers at Las Vegas Raiders

Panthers Logo
Sunday, Sep 22
4:05 p.m. ET
CBS
Raiders Logo
Panthers Odds
SpreadTotalMoneyline
+6
-112
40
-110o / -110u
+205
Raiders Odds
SpreadTotalMoneyline
-6
-108
40
-110o / -110u
-250
Odds via DraftKings. Get up-to-the-minute NFL odds here.
DraftKings Logo
  • Panthers vs. Raiders spread: Raiders -6
  • Panthers vs. Raiders over/under: 40 points
  • Panthers vs. Raiders moneyline: Raiders -265, Panthers +220
  • Panthers vs. Raiders pick, prediction: Panthers to cover the spread

Miami Dolphins at Seattle Seahawks

Dolphins Logo
Sunday, Sep 22
4:05 p.m. ET
CBS
Seahawks Logo
Dolphins Odds
SpreadTotalMoneyline
+4.5
-112
41.5
-112o / -108u
+185
Seahawks Odds
SpreadTotalMoneyline
-4.5
-108
41.5
-112o / -108u
-225
Odds via DraftKings. Get up-to-the-minute NFL odds here.
DraftKings Logo
  • Dolphins vs. Seahawks spread: Seahawks -4.5
  • Dolphins vs. Seahawks over/under: 41.5 points
  • Dolphins vs. Seahawks moneyline: Seahawks -225, Dolphins +180
  • Dolphins vs. Seahawks pick, prediction: Dolphins to cover the spread

Sunday Night Football: Kansas City Chiefs at Atlanta Falcons

Chiefs Logo
Sunday, Sep 22
8:20 p.m. ET
NBC
Falcons Logo
Chiefs Odds
SpreadTotalMoneyline
-3
-112
46.5
-110o / -110u
-162
Falcons Odds
SpreadTotalMoneyline
+3
-108
46.5
-110o / -110u
+136
Odds via DraftKings. Get up-to-the-minute NFL odds here.
DraftKings Logo
  • Chiefs vs. Falcons spread: Chiefs -3
  • Chiefs vs. Falcons over/under: 46.5 points
  • Chiefs vs. Falcons moneyline: Chiefs -165, Falcons +140
  • Chiefs vs. Falcons pick, prediction: Under the total

Monday Night Football: Jacksonville Jaguars at Buffalo Bills

Jaguars Logo
Monday, Sep 23
7:30 p.m. ET
ESPN
Bills Logo
Jaguars Odds
SpreadTotalMoneyline
+5
-108
45.5
-110o / -110u
+195
Bills Odds
SpreadTotalMoneyline
-5
-112
45.5
-110o / -110u
-238
Odds via DraftKings. Get up-to-the-minute NFL odds here.
DraftKings Logo
  • Jaguars vs. Bills spread: Bills -5
  • Jaguars vs. Bills over/under: 45.5 points
  • Jaguars vs. Bills moneyline: Bills -245, Jaguars +200
  • Jaguars vs. Bills pick, prediction: Jaguars to cover the spread

Monday Night Football: Washington Commanders at Cincinnati Bengals

Commanders Logo
Monday, Sep 23
8:15 p.m. ET
ABC
Bengals Logo
Commanders Odds
SpreadTotalMoneyline
+7
-105
47.5
-108o / -112u
+260
Bengals Odds
SpreadTotalMoneyline
-7
-115
47.5
-108o / -112u
-325
Odds via DraftKings. Get up-to-the-minute NFL odds here.
DraftKings Logo
  • Commanders vs. Bengals spread: Bengals -7.5
  • Commanders vs. Bengals over/under: 47.5 points
  • Commanders vs. Bengals moneyline: Bengals -350, Commanders +280
  • Commanders vs. Bengals pick, prediction: Over the total

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