Owls vs. 49ers Odds & Betting Predictions - October 18, 2025

Owls at 49ers

7:30 pm • ESPN+
49 - 14

Owls at 49ers Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Owls
5-7
-12.5
-10-108
o47.5-110
-370
49ers
1-11
u47.5
+10-112
u47.5-110
+300
location pinSaturday 7:30 p.m.
October 18, 2025
Jerry Richardson StadiumCharlotte
Owls vs. 49ers Expert Picks
Collin Wilson
Collin Wilson
Last 30d: 33-16-3 (+13.8u)
CHA +11.5-110
0.55u
Project Charlotte +6; Temple potentially missing multiple players on DL and LB w injury.

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Prop Odds Comparison

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Line Movement Tracker

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Owls vs. 49ers Public Betting Percentages

Away Logo

Owls

Public

42%

Bets%

58%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
49ers
5-71-54-11-03-7
Owls
7-53-34-23-14-4

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
49ers
6-64-22-31-05-5
Owls
8-43-35-14-04-4

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
49ers
1-11N/AN/A1-00-10
Owls
5-7N/AN/A4-01-7

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Oct 11th@ARMYL 7-24+17.5 WU 45.5ARMY +575
Oct 3rd@USFL 26-54+27.5 LO 54.5USF +1800
Sep 18thRICEL 17-28+1.5 LO 42.5RICE +102
Sep 13thMNMW 42-35-3 WO 66.5CHA -146
Sep 6thUNCL 3-20+15.5 LU 49.5UNC +525
Team Stats
384
Total Yards
357
53
Total Plays
76
7.245283018867925
Yards Per Play
4.697368421052632

Passing

212
YDS
158
16/23
Comps/Atts
15/29
9.217391304347826
YPA
5.448275862068965
3/0
TDs/INTs
1/1
1/8
Sacks/Yards
2/7

Rushing

172
Rush Yards
199
30
Attempts
47
5.733333333333333
YPC
4.23404255319149
2
TDs
1

Turnovers

0
Fumbles Lost
2
0
Interceptions
1

Efficiency

4/4 100%
Redzone
2/2 100%
2/9 0%
3rd Down
6/16 0%
2/2 0%
4th Down
3/4 0%

First Downs

18
Total
21
11
Pass
9
7
Rush
10
0
Penalty
2
3/40
Penalties/Yards
3/20

Owls vs. 49ers Odds Comparison

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Owls at 49ers Team Totals

MatchupOverUnder
Owls
5-7
o28.5-114
u28.5-116
49ers
1-11
o17.5-111
u17.5-116