Syracuse vs. Clemson Odds & Betting Predictions - September 20, 2025
Syracuse at Clemson
4:00 pm • ESPNSyracuse at Clemson Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
---|---|---|---|---|
![]() Syracuse 3-3 | +16.5 | +17.5-108 | o53.5-112 | +600 |
![]() Clemson 2-3 | u55.5 | -17.5-112 | u53.5-110 | -900 |

Memorial Stadium (Clemson, SC)Clemson
Syracuse vs. Clemson Expert Picks

Collin Wilson
Last 30d: 101-72-4 (+14.0u)
CLEM +7.5 (Live)-115
1.15u

Capper Central
Last 30d: 90-60-1 (+15.5u)
CLEM -16.5-118
2.36u

Wags Wins
Last 30d: 186-176-1 (-5.8u)
CLEM -16.5-118
1.25u

Brian Bitler
Last 30d: 74-79-1 (-24.3u)
CLEM -17-110
3u

Jeremiah Rose
Last 30d: 46-39-1 (+0.3u)
CLEM -16.5-115
0.25u
Boyd / FanDuel

💰🦡 Jake
Last 30d: 100-133-4 (+19.4u)
CLEM -9.5 (1H)-115
1.15u

Dan Gaspar
Last 30d: 25-29-7 (-6.7u)
T.Moore o3.5 Recs+120
1.2u

Boomer Betz
Last 30d: 135-118-2 (+22.2u)
CLEM -17+100
1u
Syracuse vs. Clemson Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Syracuse vs. Clemson Public Betting Percentages
Betting Trends
- Clemson are 2-3 in their last 5 games.
- Clemson are 1-4 in their last 5 games against the spread
- Clemson are 1-1 in their road games against the spread
- The totals have gone OVER in 2 of Clemson' last 5 games
- The totals have gone OVER in 1 of Clemson' 3 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Team Stats
433
Total Yards
503
77
Total Plays
83
5.623376623376624
Yards Per Play
6.0602409638554215
278
YDS
363
21/39
Comps/Atts
37/61
7.128205128205129
YPA
5.950819672131147
3/0
TDs/INTs
3/1
3/11
Sacks/Yards
1/1
Syracuse vs. Clemson Odds Comparison
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Syracuse at Clemson Team Totals
MatchupOverUnder | ||
---|---|---|
![]() Syracuse 3-3 | o17.5-103 | u17.5-127 |
![]() Clemson 2-3 | o35.5-114 | u35.5-114 |