Syracuse vs. Clemson Odds & Betting Predictions - September 20, 2025
Syracuse at Clemson
4:00 pm • ESPNSyracuse at Clemson Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
 Syracuse 3-5 | +16.5 | +17.5-108 | o53.5-112 | +600 |
 Clemson 3-4 | u55.5 | -17.5-112 | u53.5-110 | -900 |
Memorial Stadium (Clemson, SC)Clemson
Syracuse vs. Clemson Expert Picks
Collin Wilson
Last 30d: 84-65-1 (+15.9u)
CLEM +7.5 (Live)-115
1.15u
Capper Central
Last 30d: 78-70-0 (-6.1u)
CLEM -16.5-118
2.36u
Wags Wins
Last 30d: 214-212-1 (-11.1u)
CLEM -16.5-118
1.25u
Brian Bitler
Last 30d: 70-76-2 (-27.4u)
CLEM -17-110
3u
Jeremiah Rose
Last 30d: 26-26-0 (+0.1u)
CLEM -16.5-115
0.25u
Boyd / FanDuel
💰🦡 Jake
Last 30d: 104-120-8 (+0.2u)
CLEM -9.5 (1H)-115
1.15u
Dan Gaspar
Last 30d: 39-41-2 (-7.1u)
T.Moore o3.5 Recs+120
1.2u
Boomer Betz
Last 30d: 170-173-2 (+4.6u)
CLEM -17+100
1u
Syracuse vs. Clemson Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Syracuse vs. Clemson Public Betting Percentages
Betting Trends
- Clemson are 2-3 in their last 5 games.
- Clemson are 1-4 in their last 5 games against the spread
- Clemson are 2-1 in their road games against the spread
- The totals have gone OVER in 2 of Clemson' last 5 games
- The totals have gone OVER in 2 of Clemson' 4 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Team Stats
433
Total Yards
503
77
Total Plays
83
5.623376623376624
Yards Per Play
6.0602409638554215
278
YDS
363
21/39
Comps/Atts
37/61
7.128205128205129
YPA
5.950819672131147
3/0
TDs/INTs
3/1
3/11
Sacks/Yards
1/1
Syracuse vs. Clemson Odds Comparison
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Syracuse at Clemson Team Totals
MatchupOverUnder | ||
|---|---|---|
Syracuse 3-5 | o17.5-103 | u17.5-127 |
Clemson 3-4 | o35.5-114 | u35.5-114 |