Southern Miss vs. Louisiana Odds & Betting Predictions - October 18, 2025

Southern Miss at Louisiana

9:00 pm • ESPN+

Southern Miss Golden Eagles

22

22 - 10

Louisiana Ragin' Cajuns

10

MatchupOpenSpreadTotalMoneyline
Southern Miss 6-2	-2.5	-5-110	o54.5-110	-196
Louisiana 3-6	u54.5	+5-110	u54.5-115	+165

location pin

Saturday 9:00 p.m.

October 18, 2025

Cajun Field at Our Lady of Lourdes StadiumLafayette

Under 54.5-105

0.5u

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No props found

NCAAF Public Betting

Louisiana are 1-4 in their last 5 games.
Louisiana are 2-3 in their last 5 games against the spread
Louisiana are 2-3 in their road games against the spread
The totals have gone OVER in 2 of Louisiana' last 5 games
The totals have gone OVER in 1 of Louisiana' 4 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Louisiana	4-5	2-2	2-3	1-2	3-3
Southern Miss	5-2-1	4-1	1-1-1	4-0-1	1-2

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Louisiana	5-4	1-3	4-1	1-2	4-2
Southern Miss	5-3	4-1	1-2	4-1	1-2

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Louisiana	3-6	N/A	N/A	1-2	2-4
Southern Miss	6-2	N/A	N/A	5-0	1-2

date	opponent	score	spread	over/under	moneyline
Oct 11th	@JMU	L 14-24	+18.5 W	U 47.5	JMU +575
Sep 28th	MRSH	W 54-51	+2.5 W	O 48.5	UL -105
Sep 20th	@EMU	L 31-34	-2.5 L	O 51.5	EMU -132
Sep 13th	@MIZ	L 10-52	+27.5 L	O 47.5	MIZ +1800
Sep 7th	MCN	W 34-10	-19.5 W	U 49.5	UL -1200

Total

363

Total Yards

356

58

Total Plays

75

6.258620689655173

Yards Per Play

4.746666666666667

Passing

230

YDS

135

12/17

Comps/Atts

14/27

13.529411764705882

YPA

5

1/1

TDs/INTs

0/2

0/0

Sacks/Yards

2/11

Rushing

133

Rush Yards

221

41

Attempts

48

3.2439024390243905

YPC

4.604166666666667

1

TDs

1

Turnovers

1

Fumbles Lost

1

1

Interceptions

2

Efficiency

2/3 66.67%

Redzone

2/4 50%

2/13 0%

3rd Down

6/16 0%

1/1 0%

4th Down

1/4 0%

First Downs

14

Total

19

5

Pass

6

7

Rush

12

2

Penalty

1

Misc

6/43

Penalties/Yards

8/70

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MatchupOverUnder
Southern Miss 6-2	o30-116	u30-113
Louisiana 3-6	o24.5-103	u24.5-127