UConn vs. DePaul Odds & Betting Predictions - December 21, 2025

UConn at DePaul

9:30 pm • Fox Sports 1

Connecticut Huskies

22-2

72 - 54

DePaul Blue Demons

12-12

MatchupOpenSpreadTotalMoneyline
UConn 22-2	-14.5	-12.5-110	o133.5-110	-1000
DePaul 12-12	u136.5	+12.5-110	u133.5-110	+662

Sunday 9:30 p.m.

December 21, 2025

Wintrust ArenaChicago

CONN -6.5 (Live)-110

DEP +14.5-110

1.1u

UConn vs DePaul: Could We See a Surprise?
Jonathan Jorcin•
Dec 21, 2025 UTC

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No props found

NCAAB Public Betting

DePaul are 1-4 in their last 5 games.
DePaul are 2-3 in their last 5 games against the spread
DePaul are 7-3 in their road games against the spread
The totals have gone OVER in 1 of DePaul' last 5 games
The totals have gone OVER in 5 of DePaul' 14 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
DePaul	15-9	8-6	7-3	7-4	8-5
UConn	8-16	4-12	4-4	7-12	N/A

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
DePaul	8-16	5-9	3-7	4-7	4-9
UConn	11-13	7-9	4-4	9-10	N/A

Straight-Up (ML) History

	overall	home	away	favorite	underdog
DePaul	12-12	N/A	N/A	10-1	2-11
UConn	22-2	N/A	N/A	17-2	N/A

date	opponent	score	spread	over/under	moneyline
Dec 17th	@SJU	L 66-79	+19.5 W	U 147.5	SJU +1300
Dec 13th	@WICH	W 61-58	+6.5 W	U 144.5	DEP +234
Dec 10th	MORG	W 92-49	-22 W	U 150.5	DEP -9000
Dec 7th	ARPB	W 76-72	-23.5 L	U 156.5	DEP -8000
Nov 30th	@LSU	L 63-96	+5.5 L	O 152.5	LSU +200

Jeremy Lorenz
F
Lorenz is out with hip
Out
Amsal Delalic
G
Delalic is out for season with knee
Out for Season

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UConn

DePaul

27-57 (47%)

Field Goals

20-55 (36%)

12-16 (75%)

Free Throws

11-21 (52%)

6-18 (33%)

3-13 (23%)

Rebounds

Assists

Turnovers

Steals

Blocks

Fouls

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MatchupOverUnder
UConn 22-2	N/A	N/A
DePaul 12-12	N/A	N/A

UConn vs. DePaul Odds & Betting Predictions - December 21, 2025

UConn at DePaul

Connecticut Huskies

DePaul Blue Demons

UConn at DePaul Odds

Spread, Total, Moneyline

UConn vs. DePaul Previews & Analysis

UConn vs DePaul: Could We See a Surprise?

Prop Odds Comparison

Line Movement Tracker

UConn vs. DePaul Public Betting Percentages

UConn

Public

DePaul

Bets%

Money%

Betting Trends

Matchup History

Against the Spread (ATS) History

Over/Under History

Straight-Up (ML) History

Last 5 Matchups

UConn vs. DePaul Injury Updates

UConn Injuries

DePaul Injuries

UConn vs. DePaul Odds Comparison

UConn at DePaul Team Totals