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Duke vs. Michigan St Odds & Betting Predictions - December 6, 2025

Duke at Michigan St

5:00 pm • FOX

Duke Blue Devils

11-1
66
66 - 60

Michigan State Spartans

11-1
60

Duke at Michigan St Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Duke
11-1
-1.5+102
o141.5-110
-115
Michigan St
11-1
+1.5-122
u141.5-108
-105
location pinSaturday 5:00 p.m.
December 06, 2025
Jack Breslin Students Events CenterEast Lansing
Duke vs. Michigan St Expert Picks
FTN Fantasy
FTN Fantasy
Last 30d: 78-105-2 (-35.9u)
MSU +1.5-120
2u
The Degenerates
The Degenerates
Last 30d: 101-92-4 (+0.9u)
MSU -114
1.14u
Sean Paul
Sean Paul
Last 30d: 44-64-1 (-22.9u)
MSU +105
1u
MSU dogs at the Bres…
Roger Goodell
Roger Goodell
Last 30d: 35-53-1 (-13.7u)
MSU +2-110
0.5u
Brian Bitler
Brian Bitler
Last 30d: 82-74-1 (+6.0u)
DUKE -1.5-110
2.73u
Shane McNichol
Shane McNichol
Last 30d: 3-4-0 (-1.5u)
MSU +1.5+100
0.91u
Sean Paul
Sean Paul
Last 30d: 44-64-1 (-22.9u)
Under 142.5-110
0.91u
Article up
Moneyline Hacks
Moneyline Hacks
Last 30d: 152-106-2 (+54.4u)
MSU +1.5-105
1u
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Tickle the Twine
Tickle the Twine
Last 30d: 30-21-0 (+6.0u)
DUKE -110
0.91u

Duke vs. Michigan St Previews & Analysis

  • Our 4 CBB Best Bets For Saturday article feature image

    Our 4 CBB Best Bets For Saturday

    Action Network Staff•
    Dec 6, 2025 UTC
  • Duke vs Michigan State: Pick for Top-10 NCAAB Matchup article feature image

    Duke vs Michigan State: Pick for Top-10 NCAAB Matchup

    Sean Paul•
    Dec 6, 2025 UTC
  • 2 Spread, O/U Edges Tip at 10 ET article feature image

    2 Spread, O/U Edges Tip at 10 ET

    Alex Kolodziej•
    Dec 6, 2025 UTC
  • Upset Alert! +1845 PRO Data Parlay article feature image

    Upset Alert! +1845 PRO Data Parlay

    Action AI•
    Dec 5, 2025 UTC
See more NCAAB Coverage Right Arrow

Prop Odds Comparison

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Line Movement Tracker

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Duke vs. Michigan St Public Betting Percentages

Away Logo

Duke

Public

Home Logo

Michigan St

56%

Bets%

44%

Money%

NCAAB Public Betting Right Arrow

Betting Trends

  • Michigan St are 4-1 in their last 5 games.
  • Michigan St are 1-4 in their last 5 games against the spread
  • Michigan St are 1-1 in their road games against the spread
  • The totals have gone OVER in 2 of Michigan St' last 5 games
  • The totals have gone OVER in 3 of Michigan St' 10 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Michigan St		5-74-61-14-51-1
Duke		7-55-52-04-3N/A

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Michigan St		4-83-71-14-50-2
Duke		3-92-81-11-6N/A

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Michigan St		11-1N/AN/A9-01-1
Duke		11-1N/AN/A6-1N/A

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Dec 3rdIOWAW 71-52-5.5 WU 133.5MSU -247
Nov 27thUNCW 74-58-1.5 WU 152.5MSU -118
Nov 25thECUW 89-56-20.5 WO 142.5MSU -4500
Nov 21stDETW 84-56-30.5 LU 152.5-
Nov 18th@UKW 83-66+3.5 WU 152.5-
Team Stats

21-55 (38%)
Field Goals
21-66 (32%)
15-23 (65%)
Free Throws
10-14 (71%)
9-29 (31%)
3P
8-22 (36%)
41
Rebounds
41
12
Assists
18
8
Turnovers
5
5
Steals
5
4
Blocks
5
18
Fouls
15

Duke vs. Michigan St Odds Comparison

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Duke at Michigan St Team Totals

MatchupOverUnder
Duke
11-1
o71.5-110
u71.5-120
Michigan St
11-1
o70.5-120
u70.5-110