We have a 6-game slate today, starting early with Angels vs. Guardians at 6:10 p.m. ET and closing with Dodgers vs. Giants at 10:10 p.m. ET.
Our experts have analyzed the matchups and found great options for Monday.
Below are five expert MLB picks and predictions for today's slate of games.
MLB Best Bets Today
The team logos in the table below represent each of the matchups that our MLB betting staff is targeting from today's slate of games. Click on the team logos for any of the matchups below to navigate to a specific bet discussed in this article.
| Game | Time (ET) | Pick |
|---|---|---|
  | 6:35 PM | |
  | 7:07 PM | |
  | 8:10 PM | |
  | 10:10 PM | |
Specific betting recommendations come from the sportsbook offering preferred odds as of writing. Always shop for the best price using our MLB Odds page, which automatically surfaces the best lines for every game. | ||
Jon Anderson's Yankees vs Orioles ML Pick
By Jon Anderson
Ryan Weathers is a joy to watch pitch. A shorter frame lefty with a 96-98 mph fastball and a really good changeup. And the Yankees are enjoying his services this year. He's given them a 3.03 ERA with a 1.19 WHIP on an elite 22% K-BB%.
He'll get the nod here after being delayed a bit by illness. But even with some delays and slight injuries along the way, he's thrown at least 86 pitches in every start since his first one. So we should get a full allotment of pitches for Weathers.
The Orioles are a bottom-10 lineup in the league against lefties. The best way to measure that, in my book, is by using expected wOBA over expectation. This is a stat I developed over at MLB Data Warehouse. It takes xwOBA, a stat you're probably familiar with, and adjusts it for the pitch quality faced.
So if a team is mashing fastballs right down the middle, that's accounted for. It's a strong stat with tons of predictive power. The Orioles have a -.034 xwOBA OE against left-handed pitching this year. Only eight teams are worse. The O's are also in the bottom ten in strikeout rate against southpaws.
So it's a great spot for Weathers, and he gets the advantage of a positive park shift pitching in Camden Yards. Weathers has pitched extremely well this year, as we've detailed, and his win chances are helped by his counterpart, Brandon Young.
This is not a guy that Baltimore was hoping to have to count on as part of their rotation, but here we are. Young sports a 6.5% K-BB% (15% K%, 8.5% BB%), and he's not a guy getting ground balls either (38% GB%). Against the Yankees, who lead the league in homers and barrel rate.
Pick: Yankees ML (-172)
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Rays vs Blue Jays PRO Prop
By Action Network Staff
Aranda has a .448 average in May through nine games, with 13 hits in 29 at-bats, but only one of those was an extra-base hit.
Our projections also show a 9.2% edge on his hits prop line, but with significantly worse odds available.
He already faced Toronto last week, with five hits in nine at-bats in that series. Against tonight's starter, Kevin Gausman, he hit a single in three at-bats on May 5.
Aranda has surpassed this singles line in six of his past eight games, with more than one single in three of those contests.
At plus money, let's back him tonight to go over this line against the Blue Jays.
Pick: Jonathan Aranda 1+ Singles (+105)
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Sean Paul's Mariners vs Astros Bet
By Sean Paul
The Mariners' struggles continue. They won just four of their last 10 games and sit in third place with a 19-22 record. Perhaps a little Game 7 ALCS hangover for Seattle?
Tonight's starter, George Kirby, has been the model of consistency for the Mariners. He surrendered two or fewer runs in six of his eight starts in 2026, posting a 2.94 ERA with a 2.78 xERA and 3.44 FIP in 52 innings.
Kirby has changed his approach a bit this year. He enters this outing with a career high 57% groundball rate, up from his previous career high 44%. His sinker is his primary ground ball pitch, which he throws to right-handed hitters 33% of the time. Against lefties, he throws it just 7% of the time, while increasing his curveball usage to 18% and changeup usage to 13%.
The biggest difference between 2025 and 2026 for Kirby is a decrease in his HR/9 from 1.09 to 0.78. That, paired with Kirby's 2.09 BB/9, makes him a top-tier starter.
Seattle is getting close to nothing from Cal Raleigh, but it ranks 12th in MLB with a 100 wRC+ since April 26th. In that stretch, Raleigh has a -14 wRC+ with a .054 batting average.
Despite Raleigh struggling, Julio Rodriguez has made up for it with a 177 wRC+ and four homers in 12 games. Josh Naylor has also been a sharp free agent signing, hitting .333 with a 12% strikeout rate in his last 12.
Swing and miss remains a constant for this Mariners lineup. They rank 26th in MLB with a 24% strikeout rate this season — and not putting the ball in play is a rally killer.
I'm a tad worried about Mariners stud closer Andres Munoz. Munoz has a 6.00 ERA with a 4.99 xERA and a 3.80 FIP. It can't stay this bad, but his 1.80 HR/9 has crushed his ERA.
The Mariners had one save situation since Munoz's last outing last Tuesday — and Jose Ferrer shut the door. We'll see if Munoz gets in the mix here.
Meanwhile, the Astros had about as bad a 41-game start as anybody could've guessed, sitting at 16-25. However, they sit just 5.5 games behind the first-place Athletics in the weak AL West.
Among the few bright spots is Peter Lambert, whom Houston brought back stateside after a brief stint in the NPB. In four outings with the Astros, Lambert has a 2.42 ERA with a 3.33 xERA and a 2.82 FIP. Opponents have a .205 xBA against Lambert and boast a strong 5.3% barrel rate.
The only issue for Lambert is his 4.43 BB/9. Walks have always been an issue for him, even in the NPB. However, he strikes out 9.27 batters per nine, which should keep this swing-and-miss-heavy Mariners team off-balance.
Action PRO projects Lambert for 5.3 strikeouts tonight.
The Astros offense has been one of the best in MLB this year. They have a strong 116 wRC+, good for 5th in MLB. Hitting for power is a huge strength, as their 52 homers are fourth best in the league.
Yordan Alvarez is a huge reason for Houston's hot hitting. He has a 195 wRC+ with 13 homers and cut his strikeout rate to 13%. But don't sleep on Christian Walker, who quietly has a 147 wRC+ and nine homers after a brutal first season in H-Town.
My main concern about the Astros is their bullpen. Josh Hader is still on the injured list, and Bryan Abreu has a 9.20 ERA.
Houston has a 6.20 bullpen ERA, the lowest in MLB, and it's blown several winnable games. That's part of the calculus in betting on the Astros in 2026: You have to be ready for potential heartbreak with this shaky pen.
That's a risk I'm willing to take. Kirby is a trustworthy pitcher, but so is Lambert. From a pricing standpoint, the Astros are plus-money home underdogs against an underachieving Mariners club.
Give me the better offense at home with plus money odds to win the series opener.
Pick: Astros ML (+125, play to +100)
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Jon Anderson's Giants vs Dodgers 3-Leg Parlay
By Jon Anderson
In certain ways, it seems like a pretty solid matchup for both arms.
Trevor McDonald's pitch mix has worked on the Dodgers (relatively, at least), and Sasaki's biggest problem (the walk) isn't something you typically need to worry about against the Dodgers.
But I'm in no mood to bet on a rookie with a pretty spotty minor league resume. The Roki Sasaki walks thing is more interesting to me. He has 2, 1, and 2 walks in his last three starts with an improved 38% Ball%.
We're focusing solely on the pitchers here because they dictate so much of these games, and this game in particular. I like McDonald to log five innings, and I like Sasaki to stay under 2.5 walks.
If you want to go to a hitter, we've seen some positive signs from Rafael Devers in the recent week. He has a barrel rate above 12% in May, and this is a good spot against a righty that throws plenty of meatball fastballs.
If Devers can get ahead, he can sit on that heater and do some real damage, and he gets a positive park factor with this one being played in Los Angeles.
Picks:
- Trevor McDonald Over 14.5 Outs
- Roki Sasaki Under 2.5 Walks
- Rafael Devers Over 1.5 H+R+RBIs
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