The San Francisco Giants host the Los Angeles Dodgers on April 22, 2026. First pitch from Oracle Park is scheduled for 9:45 p.m. EDT. The game will be broadcast on SportsNet LA.
The Dodgers are favored by -210 on the moneyline and by -1.5 on the run line. The Giants are +170 on the moneyline and +1.5 on the run line. The total is set at 7.5 runs.
Find my MLB picks and Dodgers vs Giants prediction below, as well as probable pitchers, weather report, and more.
Dodgers vs Giants Prediction
- Dodgers vs Giants Pick: Under 8
My Dodgers vs Giants best bet is on the game to go under 8 runs. Make sure to find the best odds by checking our live MLB odds page.
Dodgers vs Giants Odds
| Dodgers Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 -125 | 7.5 -120o / 100u | -205 |
| Giants Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 +105 | 7.5 -120o / 100u | +170 |
- Dodgers vs Giants moneyline: Dodgers -210, Giants +170
- Dodgers vs Giants over/under: 7.5 (-120o / -102u)
- Dodgers vs Giants spread: Dodgers -1.5 (-125), Giants +1.5 (+105)
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Dodgers vs Giants Probable Pitchers
| RHP Shohei Ohtani (LAD) | Stat | RHP Tyler Mahle (SFG) |
|---|---|---|
| 2-0 | W-L | 0-3 |
| 0.7 | fWAR (FanGraphs) | -0.4 |
| 0.50/2.30 | ERA / xERA | 7.23/7.15 |
| 2.31/3.60 | FIP / xFIP | 7.00/3.85 |
| 0.72 | WHIP | 1.93 |
| 17.4% | K-BB% | 10.2% |
| 50.0% | GB% | 51.9% |
| 112 | Stuff+ | 87 |
| 94 | Location+ | 110 |
Dodgers vs Giants MLB Betting Preview
Los Angeles Dodgers Betting Preview
It's been so far, so good for Shohei Ohtani on the bump this season after slowly making his way back from Tommy John surgery a year ago. The 31-year-old has allowed just one earned run on seven hits over 18 innings, and though he's walked six over that span, he's also struck out 18.
So, Ohtani's strikeout rate is sitting at a respectable 26.1%, though that's about seven points lower than it was last year, and it's also considerably lower than any other season in his career. The good news is that, at least up until now, Ohtani is finding his groove as a ground-ball pitcher. His Pull Air % is way down from last season as a result, and he's pitched to another comfortable 2.9% barrel rate in the early going.
It'll be worth monitoring the batted ball situation for Ohtani, who's always been more of a fly-ball pitcher, considering the Dodgers have been pushing more of their arms towards pitching to gopher balls. They went from 24th in ground ball rate in 2024 to 16th last season, and while that rank has come down slightly in the early going, it certainly hasn't meant Ohtani's remained the same.
Offensively, the Dodgers have rebounded to now lead baseball in wRC+, and they've married another wonderful strikeout-to-walk ratio with a .207 Isolated Power and a .286 average. It took several of their aging stars a couple of weeks to warm up, but warm up they have.
San Francisco Giants Betting Preview
Speaking of ground-ballers, we have to talk about what's going on with Tyler Mahle. He enjoyed life in Texas, pitching to fly balls just as he's always done, because the park in Texas is hard on fly balls and the defense behind the right-hander was exceptional. Now, he's gone to San Francisco — another fly-baller's paradise, but he's begun the year by serving up a ton of ground balls.
Mahle's ground ball rate is up to 52.7% through three starts — a far cry from his 42% career average and the league average of 44.2%. He's also given up dangerous contact when the ball hasn't come back on the ground, sporting a tough 18.2% Pull Air% and 18.2% barrel rate.
The 31-year-old looks nothing like the revitalized veteran we saw last year in Texas, and even though the expected numbers suggested this was coming, I don't think this kind of regression was obvious. The ground ball rate hasn't really been dropping, either, remaining above 45% in every start. Considering the Dodgers crush ground-ballers, he should try elevating his four-seamer to generate some flyouts.
Dodgers vs Giants Pick, Betting Analysis
The first game between these two teams was low-scoring, and I believe Wednesday's will be as well. Mahle may be struggling mightily this year, but given his new ballpark — that he should lean on in a big way this go around — I don't think the issues with homers are going to persist, and with his solid track record of control, I would also expect his bloated 13.6% walk rate to drop.
The righty is just missing low a bit too much, but it's early, and he's at least trending that ground ball rate in the right direction over the last two starts. The conditions shouldn't be favorable for homers, so with that being said, there's a chance Mahle reigns in his season here.
On the opposite end, the Giants continue to look dreadful at the plate, offering us nothing in the power department with a .110 ISO and walking at just a 5.5% clip. That means for Ohtani and his expert .185 xBA, brought on by all those soft ground balls, there shouldn't be much noise coming from the other dugout either.
Pick: Under 8 (-110)
