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Cubs vs. Guardians Odds & Betting Predictions - April 5, 2026

Cubs at Guardians

5:10 pm • CLEG

Chicago Cubs

4-5
1
1 - 0

Cleveland Guardians

6-4
0
Starting Pitchers
pitcherteameraw-l
Slade Cecconi logoS.CecconiCleveland Guardians logo5.230-1
Edward Cabrera logoE.CabreraChicago Cubs logo0.001-0

Cubs at Guardians Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Cubs
4-5
PK
-1.5+144
o7.5-103
-134
Guardians
6-4
u7.5
+1.5-182
u7.5-116
+108
location pinSunday 5:10 p.m.
April 05, 2026
Progressive FieldCleveland
Cubs vs. Guardians Expert Picks
Billy Ward
Billy Ward
Last 30d: 21-30-1 (-2.4u)
Under 0.5 (1st Inn)-121
1u
The Propfessor
The Propfessor
Last 30d: 65-67-0 (+18.8u)
E.Cabrera o5.5 Ks+125
0.75u
Top Shelf Action 🥃
Top Shelf Action ��
Last 30d: 294-265-8 (+6.6u)
Under 7.5-105
0.94u
#EV Pinny -119 Circa -125
S.Cecconi u4.5 Ks-110
1.09u
#EV Pinny -137 BO -135
Picks Office
Picks Office
Last 30d: 189-199-6 (-23.8u)
Under 7.5-110
0.91u
Join Discord. All picks posted before 8am https://discord.gg/HjKxYKdSUy
Royals Props
Royals Props
Last 30d: 47-49-1 (-7.1u)
A.Bregman o1.5 Hits + Runs + RBIs-107
1.07u
Doug Ziefel
Doug Ziefel
Last 30d: 213-287-16 (-17.0u)
E.Cabrera u5.5 Ks-130
0.5u
Frank Ammirante
Frank Ammirante
Last 30d: 64-102-5 (-12.5u)
Under 4.5 (F5)-141
1u
OldSchool0909
Last 30d: 116-115-1 (+0.4u)
CLE +122
1u

Cubs vs. Guardians Previews & Analysis

  • Cubs vs Guardians: Our Bet Labs System article feature image

    Cubs vs Guardians: Our Bet Labs System

    Action Network Staff•
    Apr 5, 2026 UTC
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Prop Odds Comparison

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Line Movement Tracker

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Cubs vs. Guardians Public Betting Percentages

Away Logo

Cubs

Public

Home Logo

Guardians

66%

Bets%

34%

Money%

MLB Public Betting Right Arrow

Betting Trends

  • Guardians are 3-2 in their last 5 games.
  • Guardians are 4-1 in their last 5 games against the spread
  • Guardians are 4-3 in their road games against the spread
  • The totals have gone OVER in 1 of Guardians' last 5 games
  • The totals have gone OVER in 1 of Guardians' 3 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Guardians		7-33-04-31-06-3
Cubs		3-63-30-33-50-1

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Guardians		4-61-23-40-14-5
Cubs		4-53-31-24-40-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Guardians		6-42-14-31-05-4
Cubs		4-53-31-24-40-1

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Apr 3rdCHCW 4-1-U 7.5CLE -115
Apr 2nd@LADW 4-1+1.5 WU 8CLE +245
Apr 1st@LADL 1-4---
Mar 31st@LADW 4-2+1.5 WU 8.5CLE +158
Mar 29th@SEAL 0-8+1.5 LO 7.5SEA +122

Guardians vs. Cubs Injury Updates

Guardians Injuries

    Cubs Injuries

    • Tyler Austin
      1B

      Austin is out with knee

      Out

    • Justin Steele
      SP

      Steele is out with elbow

      Out

    • Jordan Wicks
      SP

      Wicks is out with arm

      Out

    • Seiya Suzuki
      RF

      Suzuki is out with knee

      Out

    See more MLB Injuries Right Arrow
    Cubs vs. Guardians Box Score
    Cubs Player Stats
    Projected
    PITCHERPCIPKER
    Edward Cabrera logoRE.Cabrera, P975.240
    Caleb Thielbar logoLC.Thielbar, P281.100
    Hoby Milner logoLH.Milner, P14100
    Daniel Palencia logoRD.Palencia, P13110
    HITTERSH-ABRHRRBI
    Michael Busch logo1M.Busch, 1B0-4000
    Alex Bregman logo2A.Bregman, DH0-4000
    Ian Happ logo3I.Happ, LF0-4000
    Pete Crow-Armstrong logo4P.Crow-Armstrong, CF0-4000
    Nico Hoerner logo5N.Hoerner, 2B0-2000
    Dansby Swanson logo6D.Swanson, SS0-4000
    Michael Conforto logo7M.Conforto, RF1-2000
    Dylan Carlson logo7D.Carlson, PR0-0100
    Dylan Carlson logo7D.Carlson, RF0-0100
    Matt Shaw logo8M.Shaw, 3B0-2000
    Miguel Amaya logo9M.Amaya, C1-2001
    Guardians Player Stats
    Projected
    PITCHERPCIPKER
    Slade Cecconi logoRS.Cecconi, P85660
    Tim Herrin logoLT.Herrin, P17120
    Connor Brogdon logoRC.Brogdon, P19101
    Peyton Pallette logoRP.Pallette, P15120
    HITTERSH-ABRHRRBI
    Steven Kwan logo1S.Kwan, CF0-2000
    Chase DeLauter logo2C.DeLauter, RF0-3000
    Jose Ramirez logo3J.Ramirez, DH0-3000
    Kyle Manzardo logo4K.Manzardo, 1B0-3000
    Bo Naylor logo5B.Naylor, C0-3000
    Daniel Schneemann logo6D.Schneemann, 3B0-4000
    Brayan Rocchio logo7B.Rocchio, 2B0-1000
    Gabriel Arias logo8G.Arias, SS0-3000
    CJ Kayfus logo9C.Kayfus, LF1-2000
    David Fry logo9D.Fry, PH0-1000
    Angel Martinez logo9A.Martinez, LF0-0000

    Cubs vs. Guardians Odds Comparison

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    Cubs at Guardians Team Totals

    MatchupOverUnder
    Cubs
    4-5
    N/A
    N/A
    Guardians
    6-4
    N/A
    N/A