Cardinals vs. Reds Odds & Betting Predictions - May 22, 2026

Cardinals at Reds

10:40 pm • CINR

St. Louis Cardinals

@

Cincinnati Reds

pitcher		team	era	w-l
C.Paddack			3.60	0-0
K.Leahy			3.94	5-3

MatchupOpenSpreadTotalMoneyline
Cardinals 28-21	+1.5	-1.5+154	o9.5-108	-102
Reds 26-24	u9.5	+1.5-183	u9.5-111	-116

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Friday 10:40 p.m.

May 22, 2026

Great American Ball ParkCincinnati

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68°Fahrenheit

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80%Rain

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6Wind

J.Bleday o1.5 Hits + Runs + RBIs-111

1.11u

J.Walker o1.5 Total Bases-120

$1.20

#ACTION ✍️✍️ #TotalBaseoftheDay

Under 9.5-110

1.1u

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MLB Public Betting

Reds are 2-3 in their last 5 games.
Reds are 2-3 in their last 5 games against the spread
Reds are 16-10 in their road games against the spread
The totals have gone OVER in 3 of Reds' last 5 games
The totals have gone OVER in 17 of Reds' 24 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Reds	29-21	13-11	16-10	9-6	20-15
Cardinals	30-19	15-11	15-8	3-3	27-16

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Reds	31-18-1	17-7	14-11-1	10-5	21-13-1
Cardinals	22-24-3	13-12-1	9-12-2	2-4	20-20-3

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Reds	26-24	13-11	13-13	9-6	17-18
Cardinals	28-21	13-13	15-8	3-3	25-18

date	opponent	score	spread	over/under	moneyline
May 20th	@PHI	W 9-4	+1.5 W	O 9.5	CIN +129
May 19th	@PHI	W 4-1	+1.5 W	U 8.5	CIN +122
May 18th	@PHI	L 4-5	-1.5 L	U 10	PHI +104
May 17th	@CLE	L 3-10	+1.5 L	O 8.5	CLE +135
May 16th	@CLE	L 4-7	+1.5 L	O 8.5	CLE +125

Hunter Greene
SP
Greene is out with elbow
Out

Lars Nootbaar
LF
Nootbaar is out with heel
Out
Nathan Church
LF
Nathan Church has been scratched Thursday.
Out

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PITCHER		W-L	ERA	WHIP	K/9
RK.Leahy, P		5-3	3.94	1.555	6.70

HITTERS	AVG	OBP	SLG	HR
1J.Wetherholt, 2B	.239	.357	.413	9
2I.Herrera, DH	.262	.386	.426	6
3A.Burleson, 1B	.290	.359	.468	7
4J.Walker, RF	.295	.366	.563	13
5N.Gorman, 3B	.228	.313	.367	6
6M.Winn, SS	.245	.328	.340	1
8P.Pages, C	.219	.265	.362	4
9V.Scott, CF	.185	.240	.261	2

PITCHER		W-L	ERA	WHIP	K/9
RC.Paddack, P		0-0	3.60	1.400	5.40

HITTERS	AVG	OBP	SLG	HR
1M.McLain, 2B	.208	.309	.343	5
2E.De La Cruz, SS	.290	.356	.525	11
3J.Bleday, LF	.299	.402	.636	6
4S.Stewart, 3B	.265	.353	.503	12
5S.Steer, 1B	.273	.340	.448	7
6N.Lowe, DH	.260	.330	.510	6
7W.Benson, RF	.171	.315	.303	2
8T.Stephenson, C	.183	.291	.292	3
9T.Friedl, CF	.178	.258	.260	2

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MatchupOverUnder
Cardinals 28-21	N/A	N/A
Reds 26-24	N/A	N/A