Iowa State Cyclones Odds

Iowa State Cyclones 2025 Season Preview

The Iowa State Cyclones football team enters 2025 with real momentum. After a 7-6 campaign in 2023, they blew past expectations last season, finishing 11-3, reaching the Big 12 title game, and winning the Pop-Tarts Bowl over Miami in a 42-41 shootout. It was their first bowl win since 2017 and the most wins in a season since 2020.

Matt Campbell returns for his ninth season in Ames, and while the conference is deeper than ever, the Cyclones bring back key pieces on both sides of the ball. The offense will once again be led by Rocco Becht, who threw for 3,120 yards and 27 touchdowns last season. He’s not flying solo either, Abu Sama returns as the lead back, and the WR room is stacked with names like Jaylin Noel and Benjamin Brahmer ready to level up.

On defense, Iowa State was one of the Big 12’s stingiest units in 2024. They allowed just 22.6 points per game, second-best in the conference. With Texas off to the SEC, the path to defensive dominance just got a little clearer. Their front seven remains experienced and tough, with Tyler Onyedim, J.R. Singleton, and Caleb Bacon anchoring a physical, scheme-savvy unit.

Iowa State is a legitimate contender for the Big 12 title this year, currently priced around +1200 in the market. That's not top-tier status, but it’s certainly in striking range.

Betting on the Iowa State Cyclones

Iowa State Cyclones Point Spreads

Betting point spreads means wagering on how much a team wins or loses by. Iowa State went 8-6 against the spread last season, including key covers against Cincinnati, Kansas State, and Kansas. Here’s what a spread might look like:

• Iowa State -2.5 (-110)
• Texas Tech +2.5 (-110)

In this spot, the Cyclones would need to win by 3 or more points to cash the bet. At -110 odds, a $110 wager pays $100 in profit. If Texas Tech wins outright or loses by 2 or fewer, they cover their side.

Expect plenty of tight spreads this season. With Iowa State ranked No. 39 in our college football power ratings (81.5), they’re close to a toss-up against most mid-tier Big 12 teams.

FAQ: Everything you need to know about point spreads

Iowa State Cyclones Moneylines

Moneylines are just bets on who wins the game. No spread involved. Iowa State went 11-3 straight up in 2024, and bettors who backed them in key spots, like their 30–10 win over BYU, saw solid returns.

Here’s how a moneyline might appear:

• Iowa State -160
• Oklahoma State +140

A bet on Iowa State at -160 would require a $160 stake to win $100. If you’re feeling the underdog, a $100 bet on Oklahoma State at +140 would net $140 profit. Clean and simple.

Moneyline bets are also popular in parlays. If you tie Iowa State’s moneyline to another favorite, your payout bumps up, but so does the risk. Use our Odds Calculator if you want to see how your bet stack shakes out.

FAQ: How to bet on the moneyline | How to make a parlay

Iowa State Cyclones Over/Unders

Totals, or over/unders, are wagers on the combined number of points scored in a game. In 2024, Iowa State games hit the over in 6 of 14 matchups, a jump from 25 percent in 2022 when the offense struggled.

Example line:

• Over 49.5 (-110)
• Under 49.5 (-110)

If Iowa State and their opponent combine for 50 or more points, over bettors cash. If the game lands on 49 or fewer, the under hits. Pretty straightforward.

With Becht returning and the offense looking sharper, overs could be worth tracking early in the season, especially against teams with shaky defenses.

FAQ: Betting the point total, explained | What is a push?

Iowa State Cyclones Props

Player props let you bet on individual stats, which is great if you’re already a fantasy nerd or just love watching one guy go off.

For example: Rocco Becht passing yards: 2,850.5 (Over -115 / Under -105)

If your state allows college player props, you’ll also see rushing TD totals, receiving yardage, and more. If props aren’t available where you live, check out PrizePicks, which offers a DFS-style version with similar pick formats.

FAQ: Here’s how prop betting works

Iowa State Cyclones Futures

Futures are bets on season-long outcomes. These include:

• Iowa State to win the Big 12 (+1200)
• Iowa State to make the College Football Playoff
• Iowa State to win the National Championship

They’re longshots, sure, but not crazy ones. The Cyclones reached the Big 12 title game last year, and with Becht back, they have a puncher’s chance to make another run.

For more futures markets, check our college football futures page, or compare sportsbook reviews to find the best odds and promos in your state.