Oregon vs. USC Odds & Betting Predictions - February 21, 2026
Oregon at USC
9:00 pm • Fox Sports 1Oregon at USC Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Oregon 10-17 | +4.5 | +5.5-105 | o149.5-111 | +205 |
USC 18-9 | u144.5 | -5.5-116 | u149.5-106 | -250 |

Galen CenterLos Angeles
Oregon vs. USC Expert Picks
Boomer Betz
Last 30d: 72-70-4 (+3.2u)
ORE +6-113
$100.00
Vegas Refund
Last 30d: 61-51-0 (+5.2u)
ORE +5.5-110
1u
Brian Bitler
Last 30d: 81-82-1 (-21.0u)
ORE +5.5-110
2.73u
Oregon vs. USC Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Oregon vs. USC Public Betting Percentages
Betting Trends
- USC are 2-3 in their last 5 games.
- USC are 2-3 in their last 5 games against the spread
- USC are 6-5 in their road games against the spread
- The totals have gone OVER in 3 of USC' last 5 games
- The totals have gone OVER in 9 of USC' 15 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Oregon vs. USC Injury Updates

Oregon Injuries
- Jackson ShelstadG
Shelstad is out with hand
Out
- Devon PryorF
Pryor is out with groin
Out
- Ege DemirC
Demir is out for season with undisclosed
Out for Season

USC Injuries
- Rodney RiceG
Rice is out for season with shoulder
Out for Season
- Amarion DickersonG/F
Dickerson is out with hip
Out
Team Stats
Oregon vs. USC Odds Comparison
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Oregon at USC Team Totals
MatchupOverUnder | ||
|---|---|---|
Oregon 10-17 | N/A | N/A |
USC 18-9 | N/A | N/A |



