Louisville vs. Cincinnati Odds & Betting Predictions - November 21, 2025
Louisville at Cincinnati
11:30 pm • ESPN2Louisville at Cincinnati Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
 Louisville 23-10 | -8.5-110 | o163.5-110 | -470 | |
 Cincinnati 18-15 | +8.5-110 | u163.5-115 | +355 | |
Fifth Third ArenaCincinnati
Louisville vs. Cincinnati Expert Picks
Cam Is Money
Last 30d: 26-30-0 (-8.2u)
LOU -125 (Live)
0.8u
CTO
Last 30d: 16-24-0 (-6.0u)
CIN +5.5 (1H)-110
1.82u
Ryan Minion
Last 30d: 189-219-2 (-5.2u)
M.Brown o15.5 Pts-120
$1.00
Babs .
Last 30d: 67-64-0 (-4.5u)
Under 164.5-115
0.87u
Ryan Minion
Last 30d: 189-219-2 (-5.2u)
LOU -8.5-110
$1.00
LOU -4.5 (1H)-110
$1.10
Will Brinson
Last 30d: 7-14-1 (-4.3u)
LOU -8.5-111
1u
Sean Paul
Last 30d: 29-36-0 (-9.7u)
CIN +8.5-110
1u
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Louisville vs. Cincinnati Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Louisville vs. Cincinnati Public Betting Percentages
Betting Trends
- Cincinnati are 3-2 in their last 5 games.
- Cincinnati are 2-3 in their last 5 games against the spread
- Cincinnati are 4-9 in their road games against the spread
- The totals have gone OVER in 3 of Cincinnati' last 5 games
- The totals have gone OVER in 7 of Cincinnati' 20 last games at home
Matchup History
Against the Spread (ATS) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 14-19 | 10-10 | 4-9 | 10-9 | 4-9 |
| 15-18 | 9-9 | 6-9 | 11-13 | 1-3 |
Over/Under History
| overall | home o/u | away o/u | favorite o/u | underdog o/u | |
|---|---|---|---|---|---|
| 12-20-1 | 7-12-1 | 5-8 | 7-11-1 | 4-9 |
| 12-21 | 5-13 | 7-8 | 9-15 | 1-3 |
Straight-Up (ML) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 18-15 | N/A | N/A | 15-4 | 2-11 |
| 23-10 | N/A | N/A | 17-7 | 1-3 |
Last 5 Matchups
Cincinnati vs. Louisville Injury Updates
Cincinnati Injuries
- Jalen HaynesF
Haynes is out for season with lower body
Out for Season
Louisville Injuries
- Mikel BrownG
Brown is out with back
Out
Team Stats
21-56 (38%)
Field Goals
23-62 (37%)
24-28 (86%)
Free Throws
10-16 (63%)
8-28 (29%)
3P
8-29 (28%)
35
Rebounds
35
13
Assists
19
13
Turnovers
13
9
Steals
5
4
Blocks
7
23
Fouls
19
Louisville vs. Cincinnati Odds Comparison
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Louisville at Cincinnati Team Totals
MatchupOverUnder | ||
|---|---|---|
Louisville 23-10 | N/A | N/A |
Cincinnati 18-15 | N/A | N/A |