Louisville vs. Cincinnati Odds & Betting Predictions - November 21, 2025
Louisville at Cincinnati
11:30 pm • ESPN2Louisville at Cincinnati Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
 Louisville 15-6 | -8.5-110 | o163.5-110 | -470 | |
 Cincinnati 11-11 | +8.5-110 | u163.5-115 | +355 | |
Fifth Third ArenaCincinnati
Louisville vs. Cincinnati Expert Picks
Cam Is Money
Last 30d: 56-84-3 (-32.2u)
LOU -125 (Live)
0.8u
CTO
Last 30d: 21-34-1 (-23.6u)
CIN +5.5 (1H)-110
1.82u
Ryan Minion
Last 30d: 243-291-5 (-56.3u)
M.Brown o15.5 Pts-120
$1.00
Babs .
Last 30d: 48-43-0 (+0.1u)
Under 164.5-115
0.87u
Ryan Minion
Last 30d: 243-291-5 (-56.3u)
LOU -8.5-110
$1.00
LOU -4.5 (1H)-110
$1.10
Will Brinson
Last 30d: 4-13-0 (-8.4u)
LOU -8.5-111
1u
Sean Paul
Last 30d: 52-42-0 (+6.8u)
CIN +8.5-110
1u
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Louisville vs. Cincinnati Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Louisville vs. Cincinnati Public Betting Percentages
Betting Trends
- Cincinnati are 2-3 in their last 5 games.
- Cincinnati are 2-3 in their last 5 games against the spread
- Cincinnati are 2-6 in their road games against the spread
- The totals have gone OVER in 2 of Cincinnati' last 5 games
- The totals have gone OVER in 3 of Cincinnati' 14 last games at home
Matchup History
Against the Spread (ATS) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 9-13 | 7-7 | 2-6 | 6-5 | 3-7 |
| 11-10 | 7-6 | 4-4 | 8-5 | 0-3 |
Over/Under History
| overall | home o/u | away o/u | favorite o/u | underdog o/u | |
|---|---|---|---|---|---|
| 5-16-1 | 3-10-1 | 2-6 | 2-8-1 | 2-8 |
| 7-14 | 4-9 | 3-5 | 5-8 | 0-3 |
Straight-Up (ML) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 11-11 | N/A | N/A | 9-2 | 1-9 |
| 15-6 | N/A | N/A | 10-3 | 0-3 |
Last 5 Matchups
Cincinnati vs. Louisville Injury Updates
Cincinnati Injuries
- Jalen HaynesF
Haynes is questionable with lower body
Questionable
- Sencire HarrisG
Harris is questionable with illness
Questionable
- Moustapha ThiamC
Thiam is questionable with undisclosed
Questionable
- Shon AbaevG
Abaev is questionable with undisclosed
Questionable
Louisville Injuries
- Spencer LeggG
Legg is questionable with undisclosed
Questionable
Team Stats
21-56 (38%)
Field Goals
23-62 (37%)
24-28 (86%)
Free Throws
10-16 (63%)
8-28 (29%)
3P
8-29 (28%)
35
Rebounds
35
13
Assists
19
13
Turnovers
13
9
Steals
5
4
Blocks
7
23
Fouls
19
Louisville vs. Cincinnati Odds Comparison
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Louisville at Cincinnati Team Totals
MatchupOverUnder | ||
|---|---|---|
Louisville 15-6 | N/A | N/A |
Cincinnati 11-11 | N/A | N/A |