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Iowa State vs. Purdue Odds & Betting Predictions - December 6, 2025

Iowa State at Purdue

5:00 pm • CBS

Iowa State Cyclones

15-0
81
81 - 58

Purdue Boilermakers

14-1
58

Iowa State at Purdue Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Iowa State
15-0
+4.5-112
o154.5-112
+182
Purdue
14-1
-4.5-108
u154.5-108
-220
location pinSaturday 5:00 p.m.
December 06, 2025
Mackey ArenaWest Lafayette
Iowa State vs. Purdue Expert Picks
CTO
CTO
Last 30d: 13-16-1 (-10.3u)
PUR -115 (Live)
2u
Mjaybrod
Mjaybrod
Last 30d: 80-71-0 (+4.9u)
ISU u75-105
1u
Early fade
FTN Fantasy
FTN Fantasy
Last 30d: 164-133-1 (+17.3u)
PUR -4.5-111
1u
Ryan Minion
Ryan Minion
Last 30d: 260-272-4 (-11.7u)
PUR -3 (1H)-110
$1.10

Iowa State vs. Purdue Previews & Analysis

  • Iowa State vs Purdue: Boilers Will Take Care of Ball article feature image

    Iowa State vs Purdue: Boilers Will Take Care of Ball

    Christian Odjakjian•
    Dec 6, 2025 UTC
See more NCAAB Coverage Right Arrow

Prop Odds Comparison

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Line Movement Tracker

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Iowa State vs. Purdue Public Betting Percentages

Away Logo

Iowa State

Public

Home Logo

Purdue

44%

Bets%

56%

Money%

NCAAB Public Betting Right Arrow

Betting Trends

  • Purdue are 5-0 in their last 5 games.
  • Purdue are 4-1 in their last 5 games against the spread
  • Purdue are 4-0 in their road games against the spread
  • The totals have gone OVER in 3 of Purdue' last 5 games
  • The totals have gone OVER in 5 of Purdue' 11 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Purdue		9-65-64-07-51-0
Iowa State		9-66-63-05-21-0

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Purdue		6-95-61-35-70-1
Iowa State		8-78-40-33-40-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Purdue		14-1N/AN/A11-11-0
Iowa State		15-0N/AN/A7-01-0

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Dec 3rd@RUTGW 81-65-13.5 WU 146.5PUR -1600
Nov 28thEIUW 109-62-40 WO 141.5-
Nov 22nd@TTUW 86-56-3.5 WU 154PUR -160
Nov 20thMEMW 80-71-14.5 LU 156.5PUR -1600
Nov 17thAKRW 97-79-18.5 LO 163.5PUR -2800

Iowa State vs. Purdue Injury Updates

Iowa State Injuries

  • Tamin Lipsey
    G

    Lipsey is probable with groin

    Probable

Purdue Injuries

    See more NCAAB Injuries Right Arrow
    Team Stats

    33-61 (54%)
    Field Goals
    24-59 (41%)
    4-6 (67%)
    Free Throws
    6-14 (43%)
    11-23 (48%)
    3P
    4-18 (22%)
    28
    Rebounds
    33
    19
    Assists
    17
    12
    Turnovers
    15
    6
    Steals
    7
    6
    Blocks
    2
    17
    Fouls
    10

    Iowa State vs. Purdue Odds Comparison

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    Iowa State at Purdue Team Totals

    MatchupOverUnder
    Iowa State
    15-0
    o74.5-120
    u74.5-110
    Purdue
    14-1
    o80.5-110
    u80.5-120