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Twins vs Red Sox Prediction, Pick, MLB Odds for Saturday, May 23

Twins vs Red Sox Prediction, Pick, MLB Odds for Saturday, May 23 article feature image
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May 22, 2026; Boston, Massachusetts, USA; Minnesota Twins center fielder Austin Martin (16) can’t make the catch against the Boston Red Sox during the first inning at Fenway Park. Mandatory Credit: Eric Canha-Imagn Images

The Boston Red Sox host the Minnesota Twins on May 23, 2026. First pitch from Fenway Park is scheduled for 4:10 p.m. EDT. The game will be broadcast on NESN.

The Red Sox are -116 on the moneyline. The Twins are -102 on the moneyline. The total is set at 8.5 runs.

Find my MLB picks and Twins vs Red Sox prediction below, as well as probable pitchers, weather report, and more.


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Twins vs Red Sox Prediction

  • Twins vs Red Sox Pick: Red Sox ML (-130 or Better)

Twins vs Red Sox Odds

Twins Logo
Saturday, May 23
4:10 p.m. ET
NESN
Red Sox Logo
Twins Odds
SpreadTotalMoneyline
-1.5
+164
8.5
-102o / -120u
-102
Red Sox Odds
SpreadTotalMoneyline
+1.5
-200
8.5
-102o / -120u
-116
Odds via FanDuel. Get up-to-the-minute MLB odds here.
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Twins vs Red Sox Probable Pitchers

Taj Bradley (RHP, MIN)StatJovani Morán (LHP, BOS)
4-1W-L0-1
0.9fWAR (FanGraphs)-0.1
2.87 / 3.84ERA / xERA2.81 / 3.15
3.48 / 3.88FIP / xFIP4.62 / 4.28
17.6%K-BB%14.3%
34.6%GB%36.7%
.276BABIP.193
108Stuff+98
92Location+93

Twins vs Red Sox MLB Betting Preview

This game triggered one of our Action PRO betting systems, powered by Evan Abrams:

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Evan Abrams / Bet Labs – Market Movers in Conference Clashes
the team's previous game margin is between -9 and 4
the game is a Conference game
the moneyline change from open to close is between -33 and -1
the opening moneyline is between -145 and -115
the team's Pythagorean +/- is between 1.6% and 500%
the opening total is between 7 and 9.5
$9,400
WON
1414-923-0
RECORD
61%
WIN%

This system tracks modest favorites in conference games where the market slightly shifts toward them, often due to subtle edge signals that public models do not capture.

The strategy rides light market momentum in tight, competitive spots where fundamental metrics signal a long-term edge.


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Twins vs Red Sox Pick, Betting Analysis

I’m no believer in Brayan Bello, but he has been markedly better when following an opener this season. He’s piggybacked Jovani Moran twice this season, tossing 13 ⅓ two-run innings against the Phillies and Tigers (two good offenses) with 12 strikeouts to two walks.

Taj Bradley is fine, but his botERA (4.58) and BABIP/strand rates (.276/84.3%) signal some regression.

Boston’s lineup is an abomination, but Minnesota’s bats have regressed after their red-hot start, posting a .300 xwOBA in May after a .323 in April.

Meanwhile, the Red Sox have huge advantages in the bullpen (Minnesota’s relievers are bad) and on defense (Boston is the best in the league in that regard).

While Justin Slaten blew yesterday’s game, at least the Red Sox got to rest Aroldis Chapman and Garrett Whitlock, which should really help today.

Ultimately, I project the Red Sox ML close to -140.

Pick: Red Sox ML (-130 or Better)


Twins vs Red Sox Weather


Get the latest coverage on MLB Weather.
Author Profile
About the Author

Tanner McGrath covers college basketball, college football and Major League Baseball at Action Network. He is a contributor to Payoff Pitch, Action Network’s Major League Baseball betting podcast. He's been working in the space for more than five years with past journalism experience in Canadian collegiate sports, finance and economics. He has an obsession with America East basketball, betting the Miami Marlins and sweating out home underdogs.

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