The Cincinnati Reds host the Chicago Cubs on Friday, May 23, 2025. First pitch from Great American Ball Park is scheduled for 6:40 p.m. ET; the game will be broadcast on Marquee and FanDuel Sports Ohio.
Find my Cubs vs Reds predictions and parlay picks for this NL Central clash on Friday night below.
Cubs vs Reds Predictions, Parlay Picks
- Matthew Boyd Over 17.5 Pitching Outs
- Cubs Moneyline
Parlay odds: +180 (Fanatics)
Cubs vs Reds Odds, Lines
| Chicago Cubs Odds | ||
|---|---|---|
| Run Line | Total | Moneyline |
-1.5 +143 | 8.5 -105o / -115u | -115 |
| Cincinnati Reds Odds | ||
|---|---|---|
| Run Line | Total | Moneyline |
+1.5 -170 | 8.5 -105o / -115u | -105 |
Cubs vs Reds Projected Starting Pitchers
| LHP Matthew Boyd (CHC) | Stat | RHP Hunter Greene (CIN) |
|---|---|---|
| 4-2 | W-L | 4-2 |
| 0.8 | fWAR (FanGraphs) | 1.3 |
| 2.98/3.40 | ERA /xERA | 2.36/2.45 |
| 3.84/3.81 | FIP / xFIP | 3.06/2.90 |
| 1.23 | WHIP | 0.81 |
| 18.7 | K-BB% | 30.1 |
| 34.5 | GB% | 30.5 |
| 95 | Stuff+ | 126 |
| 103 | Location+ | 101 |
Cubs vs Reds Parlay Picks, Preview
Matthew Boyd Over 17.5 Pitching Outs
Friday night action starts with the Cubs traveling to face their division rival, Reds. The series opens with a solid pitching duel between Hunter Greene and Matthew Boyd.
We’re backing Boyd to record at least 18 outs (six full innings). He’s been consistent this season, clearing this line in three straight starts and four of his last five.
His biggest strength has been limiting baserunners, and he’s proven capable of doing just that.
Boyd owns a sub-3.00 ERA and has tallied 23 strikeouts over his last three outings.
The Reds' offense has struggled to produce runs lately, and we expect that trend to continue on Friday.
Cubs Moneyline
We’re also backing the Cubs to win outright.
