White Sox vs. Diamondbacks Odds & Betting Predictions - April 22, 2026

White Sox at Diamondbacks

1:40 am • CHSN
7 - 0

White Sox at Diamondbacks Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
White Sox
8-14
+1.5
+1.5-161
o9-117
+120
Diamondbacks
13-9
u9.5
-1.5+138
u9-105
-144
location pinWednesday 1:40 a.m.
April 22, 2026
Chase FieldPhoenix
White Sox vs. Diamondbacks Expert Picks
Cam Is Money
Cam Is Money
Last 30d: 107-89-4 (+16.5u)
M.Murakami o1.5 Hits + Runs + RBIs-115
1u
OldSchool0909
Last 30d: 147-157-0 (+13.4u)
CWS +135
1u
The Degenerates
The Degenerates
Last 30d: 85-86-6 (-5.5u)
ARI -1.5+135
1u
Wags Wins
Wags Wins
Last 30d: 209-233-2 (-11.6u)
Over 9.5+105
1u
Billy Ward
Billy Ward
Last 30d: 37-38-4 (-1.6u)
Over 0.5 (1st Inn)-118
1.18u
Wouldn't go much past this
Doug Ziefel
Doug Ziefel
Last 30d: 278-373-23 (-23.2u)
M.Kelly o4.5 Ks-115
0.58u
RoyalsProps
RoyalsProps
Last 30d: 62-56-6 (+0.8u)
I.Vargas o1.5 Hits + Runs + RBIs-112
1.12u
Doug Ziefel
Doug Ziefel
Last 30d: 278-373-23 (-23.2u)
Under 9.5-110
0.55u

White Sox vs. Diamondbacks Previews & Analysis

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Prop Odds Comparison

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Line Movement Tracker

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White Sox vs. Diamondbacks Public Betting Percentages

Away Logo

White Sox

Public

12%

Bets%

88%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Diamondbacks
17-57-310-25-111-4
White Sox
10-124-56-7N/A10-12

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Diamondbacks
13-8-16-47-4-13-39-5-1
White Sox
14-85-49-4N/A14-8

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Diamondbacks
13-97-36-65-17-8
White Sox
8-143-65-8N/A8-14

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Apr 19thTORL 4-10+1.5 LO 8TOR -101
Apr 19thTORW 6-2-1.5 WU 9ARI -151
Apr 18thTORW 6-3-1.5 WO 8.5ARI -142
Apr 15th@BALW 8-5+1.5 WO 9ARI +119
Apr 14th@BALW 4-3+1.5 WU 8.5ARI +135

White Sox vs. Diamondbacks Injury Updates

White Sox Injuries

  • Mike Vasil
    RP

    Vasil is out with elbow

    Out

  • Ky Bush
    SP

    Bush is out with elbow

    Out

  • Brooks Baldwin
    LF

    Baldwin is out with elbow

    Out

  • Kyle Teel
    C

    Teel is out with hamstring

    Out

  • Drew Thorpe
    SP

    Thorpe is out with elbow

    Out

Diamondbacks Injuries

  • Corbin Burnes
    SP

    Burnes is out with elbow

    Out

  • Blake Walston
    SP

    Walston is out with elbow

    Out

  • Tyler Locklear
    1B

    Locklear is out with elbow

    Out

  • Cristian Mena
    SP

    Mena is doubtful with shoulder

    Doubtful

White Sox vs. Diamondbacks Box Score
White Sox Player Stats
Projected
PITCHERPCIPKER
Sean Burke logoRS.Burke, P60320
HITTERSH-ABRHRRBI
Andrew Benintendi logo1A.Benintendi, DH2-3100
Munetaka Murakami logo2M.Murakami, 1B2-2211
Miguel Vargas logo3M.Vargas, 3B1-1211
Colson Montgomery logo4C.Montgomery, SS2-2213
Everson Pereira logo5E.Pereira, RF0-1001
Sam Antonacci logo6S.Antonacci, LF1-2001
Chase Meidroth logo7C.Meidroth, 2B1-2000
Tristan Peters logo8T.Peters, CF0-2000
Reese McGuire logo9R.McGuire, C0-2000
Diamondbacks Player Stats
Projected
PITCHERPCIPKER
Merrill Kelly logoRM.Kelly, P76347
HITTERSH-ABRHRRBI
Ketel Marte logo1K.Marte, 2B1-2000
Corbin Carroll logo2C.Carroll, RF0-2000
Geraldo Perdomo logo3G.Perdomo, SS0-0000
Adrian Del Castillo logo4A.Del Castillo, C0-1000
Lourdes Gurriel logo5L.Gurriel, LF0-1000
Jose Fernandez logo6J.Fernandez, DH0-1000
Nolan Arenado logo7N.Arenado, 3B1-1000
Ildemaro Vargas logo8I.Vargas, 1B0-1000
Alek Thomas logo9A.Thomas, CF1-1000

White Sox vs. Diamondbacks Odds Comparison

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White Sox at Diamondbacks Team Totals

MatchupOverUnder
White Sox
8-14
N/A
N/A
Diamondbacks
13-9
N/A
N/A