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Twins vs. Guardians Odds & Betting Predictions - May 8, 2026

Twins at Guardians

11:15 pm • Apple TV+

Minnesota Twins

16-22
@

Cleveland Guardians

20-19
Starting Pitchers
pitcherteameraw-l
Parker Messick logoP.MessickCleveland Guardians logo2.403-1
Connor Prielipp logoC.PrielippMinnesota Twins logo3.861-0

Twins at Guardians Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Twins
16-22
+1.5
+1.5-188
o7.5-110
+119
Guardians
20-19
u7.5
-1.5+156
u7.5-110
-140
location pinFriday 11:15 p.m.
May 08, 2026
Progressive FieldCleveland
thermometer image55°Fahrenheit
rain image45%Rain
wind image6Wind
Twins vs. Guardians Expert Picks
Sean Zerillo
Sean Zerillo
Last 30d: 156-145-17 (-2.9u)
Under 7.5+105
0.5u
Bet to -118

Prop Odds Comparison

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Line Movement Tracker

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Twins vs. Guardians Public Betting Percentages

Away Logo

Twins

Public

Home Logo

Guardians

22%

Bets%

78%

Money%

MLB Public Betting Right Arrow

Betting Trends

  • Guardians are 2-3 in their last 5 games.
  • Guardians are 2-3 in their last 5 games against the spread
  • Guardians are 11-12 in their road games against the spread
  • The totals have gone OVER in 2 of Guardians' last 5 games
  • The totals have gone OVER in 6 of Guardians' 16 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Guardians		21-1810-611-1210-911-9
Twins		18-2010-108-104-614-13

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Guardians		19-206-1013-109-1010-10
Twins		22-13-311-6-311-77-314-10-3

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Guardians		20-199-711-1210-910-10
Twins		16-2210-106-124-612-15

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
May 7th@KCW 8-5---
May 6th@KCW 3-1+1.5 WU 7.5CLE +116
May 5th@KCL 3-5-1.5 LO 7.5KC -117
May 4th@KCL 2-6-U 9KC +100
May 3rd@ATHL 1-7-1.5 LU 9ATH -126

Guardians vs. Twins Injury Updates

Guardians Injuries

    Twins Injuries

    • Pablo Lopez
      SP

      Lopez is out with elbow

      Out

    • David Festa
      SP

      Festa is out with shoulder

      Out

    • Travis Adams
      SP

      Adams is out with triceps

      Out

    See more MLB Injuries Right Arrow
    Twins vs. Guardians Starting Lineups
    Twins Starting Lineup
    Projected
    PITCHERW-LERAWHIPK/9
    Connor Prielipp logoLC.Prielipp, P1-03.860.9299.64
    HITTERSAVGOBPSLGHR
    Byron Buxton logo1B.Buxton, CF.243.298.51411
    Austin Martin logo2A.Martin, LF.317.457.4021
    Ryan Jeffers logo3R.Jeffers, C.302.409.5315
    Josh Bell logo4J.Bell, DH.217.297.3333
    Victor Caratini logo5V.Caratini, 1B.207.305.2531
    Luke Keaschall logo6L.Keaschall, 2B.234.310.3141
    Royce Lewis logo7R.Lewis, 3B.169.270.3123
    Brooks Lee logo8B.Lee, SS.270.326.4345
    Matt Wallner logo9M.Wallner, RF.185.285.3244
    Guardians Starting Lineup
    Projected
    PITCHERW-LERAWHIPK/9
    Parker Messick logoLP.Messick, P3-12.400.9199.58
    HITTERSAVGOBPSLGHR
    Steven Kwan logo1S.Kwan, CF.212.306.2701
    Angel Martinez logo2A.Martinez, LF.270.311.4685
    Jose Ramirez logo3J.Ramirez, 3B.211.341.3946
    Rhys Hoskins logo4R.Hoskins, 1B.200.343.3763
    Chase DeLauter logo5C.DeLauter, DH.306.392.5486
    David Fry logo6D.Fry, RF.239.375.4573
    Travis Bazzana logo7T.Bazzana, 2B.192.382.1920
    Austin Hedges logo8A.Hedges, C.311.360.4671
    Brayan Rocchio logo9B.Rocchio, SS.262.343.3693

    Twins vs. Guardians Odds Comparison

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    Twins at Guardians Team Totals

    MatchupOverUnder
    Twins
    16-22
    N/A
    N/A
    Guardians
    20-19
    N/A
    N/A