Padres vs. White Sox Odds & Betting Predictions - September 21, 2025

Padres at White Sox

6:10 pm • SDPA

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San Diego Padres

@

Chicago White Sox

pitcher		team	era	w-l
S.Burke			4.29	4-10
M.King			3.84	4-3

MatchupOpenSpreadTotalMoneyline
Padres 84-71	-1.5	-1.5-105	o8-113	-180
White Sox 58-97	u8	+1.5-115	u8-110	+149

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Sunday 6:10 p.m.

September 21, 2025

Rate FieldChicago

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78°Fahrenheit

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0%Rain

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8Wind

CWS +158

0.5u

Bet to +145

No props found

MLB Public Betting

White Sox are 1-4 in their last 5 games.
White Sox are 2-3 in their last 5 games against the spread
White Sox are 44-31 in their road games against the spread
The totals have gone OVER in 2 of White Sox' last 5 games
The totals have gone OVER in 42 of White Sox' 80 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
White Sox	90-65	46-34	44-31	0-2	88-63
Padres	82-73	40-35	42-38	40-47	41-26

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
White Sox	72-76-7	42-33-5	30-43-2	0-2	70-74-7
Padres	66-85-4	31-43-1	35-42-3	43-42-2	23-42-2

Straight-Up (ML) History

	overall	home	away	favorite	underdog
White Sox	58-97	33-47	25-50	1-1	56-95
Padres	84-71	47-28	37-43	51-36	32-35

date	opponent	score	spread	over/under	moneyline
Sep 20th	SD	L 3-7	+1.5 L	O 8	SD +153
Sep 19th	SD	W 4-3	-	-	-
Sep 17th	BAL	L 1-3	+1.5 L	U 8.5	BAL +104
Sep 16th	BAL	L 7-8	+1.5 W	O 8	BAL -110
Sep 15th	BAL	L 1-4	+1.5 L	U 8	BAL +117

Ky Bush
SP
Bush is out with elbow
Out
Drew Thorpe
SP
Thorpe is out with elbow
Out

Joe Musgrove
SP
Musgrove is out for season with elbow
Out for Season

See more MLB Injuries

PITCHER		W-L	ERA	WHIP	K/9
RM.King, P		4-3	3.84	1.173	9.46

HITTERS	AVG	OBP	SLG	HR
1F.Tatis, RF	.266	.367	.433	22
2L.Arraez, 2B	.286	.320	.384	7
3M.Machado, 3B	.276	.336	.462	26
4J.Merrill, CF	.263	.316	.455	15
5R.Laureano, LF	.290	.355	.529	15
6G.Sheets, DH	.258	.324	.445	19
7R.O'Hearn, 1B	.283	.374	.463	13
8J.Cronenworth, SS	.250	.372	.388	11
9F.Fermin, C	.255	.309	.339	3

PITCHER		W-L	ERA	WHIP	K/9
RS.Burke, P		4-10	4.29	1.468	8.50

HITTERS	AVG	OBP	SLG	HR
1C.Meidroth, 2B	.267	.343	.338	5
2K.Teel, DH	.277	.375	.429	8
3C.Montgomery, SS	.220	.294	.493	18
4M.Vargas, 3B	.230	.310	.400	15
5M.Tauchman, RF	.263	.356	.400	9
6E.Quero, C	.275	.340	.370	5
7L.Sosa, 1B	.261	.291	.428	21
8W.Robertson, LF	.100	.250	.100	0
9M.Taylor, CF	.201	.259	.363	8

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MatchupOverUnder
Padres 84-71	N/A	N/A
White Sox 58-97	N/A	N/A