Cardinals vs. Astros Odds & Betting Predictions - February 22, 2026

Cardinals at Astros

6:05 pm • SCHN

St. Louis Cardinals

6

6 - 5

Houston Astros

5

pitcher		team	era	w-l
M.Burrows			1.50	1-0
K.Leahy			4.59	1-1

MatchupOpenSpreadTotalMoneyline
Cardinals 38-31	+1.5	+1.5-190	o10.5-105	+102
Astros 33-40	u10.5	-1.5+160	u10.5-118	-118

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Sunday 6:05 p.m.

February 22, 2026

The Ballpark of the Palm BeachesWest Palm Beach

No props found

MLB Public Betting

Astros are 2-3 in their last 5 games.
Astros are 3-2 in their last 5 games against the spread
Astros are 18-20 in their road games against the spread
The totals have gone OVER in 3 of Astros' last 5 games
The totals have gone OVER in 21 of Astros' 35 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Astros	34-39	16-19	18-20	6-15	28-23
Cardinals	43-26	21-14	22-12	8-4	35-21

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Astros	38-31-4	21-13-1	17-18-3	12-9	25-22-4
Cardinals	30-35-4	17-16-2	13-19-2	5-6-1	24-29-3

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Astros	33-40	16-19	17-21	8-13	25-26
Cardinals	38-31	19-16	19-15	9-3	29-27

date	opponent	score	spread	over/under	moneyline
Feb 21st	@WSH	L 1-2	-	-	-
Sep 28th	@LAA	W 6-2	-1.5 W	U 9	HOU -117
Sep 28th	@LAA	W 6-1	-1.5 W	U 9	HOU -146
Sep 27th	@LAA	L 3-4	-1.5 L	U 9	LAA -133
Sep 25th	@ATH	W 11-5	-1.5 W	O 9.5	HOU -119

Lance McCullers
SP
Lance McCullers Jr. has been scratched Tuesday. Jason Alexander will start.
Out

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PITCHER		PC	IP	K	ER
RK.Leahy, P		29	2	3	1
RC.Roycroft, P		10	1	0	0
M.Rajcic, P		23	2	1	0
RS.Blewett, P		20	1	1	1
G Moreno, P		19	1	2	0
LN. Raquet, P		12	1	2	0

HITTERS	H-AB	R	HR	RBI
1V.Scott, CF	0-2	0	0	0
1M. Ugueto, CF	0-2	0	0	0
2T.Saggese, SS	1-3	1	0	1
2B.Moore, SS	1-2	0	0	0
3J.Walker, RF	1-2	2	0	0
3C. Ledbetter, RF	0-2	0	0	0
4N.Velazquez, LF	1-2	2	0	0
4M.Antico, LF	0-2	0	0	0
5Y.Pozo, C	1-2	0	0	2
5A.Yerzy, C	1-2	0	0	0
6C.Prieto, 3B	0-3	0	0	2
6R.Mendoza, 2B	1-2	0	0	0
7B.Torres, 2B	0-2	0	0	0
8B.Jordan, 1B	0-2	0	0	0
9C.Davis, PH	0-1	0	0	0
9C.Davis, DH	0-1	0	0	0

PITCHER		PC	IP	K	ER
RM.Burrows, P		24	2	2	0
RR.Munoz, P		21	1	1	2
RJ.Murray, P		18	1	1	0
RC.Bolton, P		27	0.2	0	1
RA.Maldonado, P		6	1.1	0	0
RC.Roa, P		16	1	1	0
RA.Willingham, P		17	1	1	0

HITTERS	H-AB	R	HR	RBI
1J.Pena, SS	0-2	0	0	0
1R. Unroe, SS	2-3	0	0	1
1R. Unroe, 2B	2-3	0	0	1
2T.Trammell, LF	0-2	0	0	0
3J.Meyers, CF	1-3	0	0	1
4E.Frey, DH	0-3	0	0	0
6J.Winkler, 3B	1-2	1	1	1
6P.Ferreras, 3B	0-1	1	0	0
7J.Biggers, 2B	0-2	0	0	0
8C.Price, 1B	1-2	0	0	0
8Z.Daudet, 1B	1-1	1	0	0
9J. Garcia, C	0-1	0	0	1

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MatchupOverUnder
Cardinals 38-31	N/A	N/A
Astros 33-40	N/A	N/A