| Alex Berenguer | F | Out | Suspended | Suspended | Feb 27 |
| Yuri Berchiche | DEF | Out | Suspended | Suspended | Feb 11 |
| Andoni Gorosabel | DEF | Out | Andoni Gorosabel is expected to return Mid April 2026 from Thigh injury. | Gorosabel is out with thigh | Apr 4 |
| Inigo Ruiz De Galarreta | MID | Out | Inigo Ruiz de Galarreta is expected to return Late March 2026 from Shoulder injury. | Ruiz De Galarreta is out with shoulder | Feb 28 |
| Aitor Paredes | DEF | Out | Aitor Paredes is expected to return Mid April 2026 from Leg injury. | Paredes is out with leg | Mar 29 |
| Benat Prados | MID | Doubtful | Beñat Prados is Doubtful with Cruciate ligament injury. | Prados is doubtful with knee | Mar 20 |
| Ademola Lookman | F | Out indefinitely | Illness | Illness | Dec 27 |
| Koke | MID | Out indefinitely | Hamstring | Hamstring | Nov 9 |
| Pablo Barrios | MID | Out indefinitely | None | Barrios Rivas is injured | Dec 2 |
| Ilias Kostis | DEF | Out for season | Ilias Kostis is Out for season with Cruciate ligament injury. | Kostis is out for season with knee | Dec 5 |
| Robert Lewandowski | F | Out indefinitely | Hamstring | Hamstring | Mar 14 |
| Andreas Christensen | DEF | Out indefinitely | Andreas Christensen is Unknown with Cruciate ligament injury. | Christensen is injured with knee | Dec 21 |
| Frenkie De Jong | MID | Out | Frenkie De Jong is expected to return Mid April 2026 from Thigh injury. | De Jong is out with thigh | Apr 5 |
| Daniel Rodriguez | MID | Out | Dani Rodriguez is expected to return Early May 2026 from Ligament injury. | Rodriguez is out with ligament | Feb 27 |
| Jofre Torrents | DEF | Out | Jofre Torrents is expected to return Early May 2026 from Calf injury. | Torrents is out with calf | Feb 23 |
| Javier Ontiveros | F | Out | Shoulder Injury | Shoulder Injury | Apr 27 |
| Lucas Boye | F | Out | Suspended | Suspended | Apr 1 |
| Mariano Diaz | F | Out indefinitely | Ankle/Foot Injury | Ankle/Foot Injury | Jan 13 |
| Carlos Benavidez | MID | Out | Carlos Benavidez is expected to return Mid April 2026 from Leg injury. | Benavidez is out with leg | Mar 31 |
| Raul Fernandez | GK | Doubtful | None | Fernandez is doubtful | May 18 |
| Pedro Bigas | DEF | Suspended | Pedro Bigas is serving a suspension for Yellow/red card. | Bigas is suspended with yellow/red card | Apr 4 |
| Rafa Mir | F | Out indefinitely | Knock | Knock | Apr 4 |
| Tete Morente | F | Out indefinitely | Toe Injury | Toe Injury | Feb 16 |
| Victor Chust | DEF | Doubtful | Víctor Chust is Doubtful with Physical discomfort. | Chust is doubtful with soreness | Mar 30 |
| John Nwankwo Donald | MID | Doubtful | John Donald Chetauya is Doubtful with Muscle injury. | Nwankwo Donald is doubtful with muscle | Mar 10 |
| Hector Fort | DEF | Doubtful | Héctor Fort is Doubtful with Shoulder injury. | Fort is doubtful with shoulder | Mar 9 |
| Javi Puado | MID | Out for season | Javi Puado is Out for season with Cruciate ligament injury. | Puado is out for season with knee | Jan 12 |
| Borja Mayoral | F | Doubtful | Borja Mayoral is Doubtful with Knee injury. | Mayoral is doubtful with knee | Feb 20 |
| Mauro Arambarri | MID | Suspended | Mauro Arambarri is serving a suspension for Yellow cards. | Arambarri is suspended with yellow cards | Apr 5 |
| Juanmi | F | Doubtful | Juanmi Jimenez is Doubtful with Muscle injury. | Juanmi is doubtful with muscle | Mar 13 |
| Martin Satriano | F | Out indefinitely | None | Satriano is injured | Feb 13 |
| Daley Blind | DEF | Out indefinitely | Ankle/Foot Injury | Ankle/Foot Injury | Jun 15 |
| Thomas Lemar | MID | Out indefinitely | Knee Injury | Knee Injury | Feb 27 |
| Marc-Andre Ter Stegen | GK | Out indefinitely | Illness | Illness | May 10 |
| Ruben Blanco | GK | Out indefinitely | Illness | Illness | May 9 |
| Portu | F | Out for season | Portu is Out for season with Cruciate ligament injury. | Portu is out for season with knee | Dec 5 |
| Ugo Raghouber | MID | Out | Ugo Raghouber is expected to return Late January 2026 from Ankle injury. | Raghouber is out with ankle | Jan 2 |
| Unai Vencedor | MID | Doubtful | Unai Vencedor is Doubtful with Muscle injury. | Vencedor is doubtful with muscle | Apr 3 |
| Brugue | MID | Doubtful | Roger Brugué is Doubtful with Ligament injury. | Brugue is doubtful with ligament | Mar 29 |
| Diego Pampin | F | Doubtful | Diego Pampin is Doubtful with Muscle injury. | Pampin is doubtful with muscle | Apr 3 |
| Omar Mascarell | MID | Out | Suspended | Suspended | Feb 15 |
| Sergi Darder | MID | Out | Virus | Virus | Jan 17 |
| Takuma Asano | F | Out indefinitely | Knee Injury | Knee Injury | Nov 11 |
| Pablo Maffeo | DEF | Out | Suspended | Suspended | Nov 9 |
| Martin Valjent | DEF | Out indefinitely | Back Injury | Back Injury | Apr 11 |
| Vedat Muriqi | F | Out indefinitely | Ankle/Foot Injury | Ankle/Foot Injury | Nov 28 |
| Antonio Raillo | DEF | Out indefinitely | Antonio Raíllo is Unknown with Thigh injury. | Raillo is injured with thigh | Apr 6 |
| M. Peybernes | DEF | Out | Suspended | Suspended | Feb 19 |
| Juanfran | DEF | Out indefinitely | Hamstring | Hamstring | Nov 26 |
| Weligton Róbson Pena de Oliveira | DEF | Out indefinitely | Knee Injury | Knee Injury | Jun 9 |
| Juan Carlos Pérez López | DEF | Out | Suspended | Suspended | Jan 5 |
| Miguel Torres Gómez | DEF | Out | Hamstring | Hamstring | May 24 |
| Sérgio Paulo Barbosa Valente | MID | Out indefinitely | Toe Injury | Toe Injury | May 22 |
| Keko | MID | Out indefinitely | Thigh Muscle Strain | Thigh Muscle Strain | May 5 |
| Zdravko Kuzmanović | MID | Out indefinitely | Pubalgia | Pubalgia | Jun 12 |
| Jozabed | MID | Out | Suspended | Suspended | Jan 22 |
| Pablo Hervías | MID | Out indefinitely | Cartilage Knee Injury | Cartilage Knee Injury | Apr 6 |
| Adrián | A | Out indefinitely | Knock | Knock | Jun 15 |
| Brandon Thomas Llamas | A | Out | Suspended | Suspended | Jan 3 |
| C. Gönen | GK | Out indefinitely | Shoulder Injury | Shoulder Injury | Jun 12 |
| L. Agbenyenu | DEF | Out indefinitely | Calf Muscle Strain | Calf Muscle Strain | Jul 17 |
| Joaquín Muñoz | A | Out | Suspended | Suspended | Mar 27 |
| P. Chavarría | A | Out indefinitely | Knock | Knock | Sep 29 |
| E. Burgos | DEF | Out | Suspended | Suspended | Feb 20 |
| M. Benkhemassa | MID | Out | Suspended | Suspended | Jan 26 |
| Caye Quintana | A | Out | Suspended | Suspended | Dec 5 |
| Jonás Ramalho | DEF | Out indefinitely | Calf Muscle Strain | Calf Muscle Strain | Nov 22 |
| Genaro Rodríguez | MID | Out | Suspended | Suspended | Jan 15 |
| Lucas Torro | MID | Out indefinitely | Ankle/Foot Injury | Ankle/Foot Injury | May 23 |
| Iker Benito | F | Out for season | Iker Benito is Out for season with Cruciate ligament injury. | Benito is out for season with knee | Dec 5 |
| Asier Osambela | MID | Suspended | Asier Osambela is serving a suspension for Red card. | Osambela is suspended with red card | Apr 5 |
| Flavien Boyomo | DEF | Suspended | Flavien Enzo Boyomo is serving a suspension for Yellow cards. | Boyomo is suspended with yellow cards | Apr 5 |
| M. Koné | A | Out | Suspended | Suspended | Jan 12 |
| Raúl Carnero | DEF | Out | Suspended | Suspended | Mar 19 |
| Fernando Navarro i Corbacho | DEF | Out | Suspended | Suspended | Apr 1 |
| Rober | DEF | Out indefinitely | Knock | Knock | Nov 29 |
| Ivan Balliu | DEF | Out | Suspended | Suspended | Oct 17 |
| Oscar Trejo | F | Out | Calf Muscle Strain | Calf Muscle Strain | Jun 5 |
| Fran Perez | MID | Doubtful | Fran Perez is Doubtful with Physical discomfort. | Perez is doubtful with soreness | Mar 31 |
| Luiz Felipe | DEF | Out indefinitely | Hamstring | Hamstring | Apr 4 |
| Ilias Akhomach | F | Doubtful | Ilias Akhomach is Doubtful with Thigh injury. | Akhomach is doubtful with thigh | Mar 25 |
| Thibaut Courtois | GK | Out indefinitely | Hamstring | Hamstring | Feb 20 |
| Dani Ceballos | MID | Out indefinitely | Hamstring | Hamstring | Oct 31 |
| Dani Carvajal | DEF | Out indefinitely | Hamstring | Hamstring | Jan 30 |
| Ferland Mendy | DEF | Out indefinitely | Calf Muscle Strain | Calf Muscle Strain | Apr 11 |
| Rodrygo | F | Out | Rodrygo is expected to return Mid December 2026 from Cruciate ligament injury. | Rodrygo is out with knee | Mar 3 |
| Raul Asencio | DEF | Suspended | Raúl Asencio is serving a suspension for Red card. | Asencio is suspended with red card | Feb 13 |
| Eric Bailly | DEF | Out | Suspended | Suspended | Feb 13 |
| Leander Dendoncker | MID | Out | Knock | Knock | Mar 12 |
| Alex Fores | F | Out | Alex Forés is expected to return Mid April 2026 from Muscle injury. | Fores is out with muscle | Apr 4 |
| Ovie Ejaria | F | Doubtful | Ovie Ejaria is Doubtful with Muscle injury. | Ejaria is doubtful with muscle | Mar 18 |
| Lucas Ahijado | DEF | Doubtful | Lucas Ahijado is Doubtful with Muscle injury. | Ahijado is doubtful with muscle | Mar 10 |
| Igor Zubeldia | MID | Out | Igor Zubeldia is expected to return Mid April 2026 from Hamstring Injury. | Zubeldia is out with hamstring | Mar 20 |
| Alvaro Odriozola | DEF | Out for season | Álvaro Odriozola is Out for season with Cruciate ligament injury. | Odriozola is out for season with knee | Feb 23 |
| Yangel Herrera | MID | Out indefinitely | Calf Muscle Strain | Calf Muscle Strain | Apr 4 |
| Unai Marrero | GK | Doubtful | Unai Marrero is Doubtful with Broken cheekbone. | Marrero is doubtful with face | Feb 9 |
| Jon Martin | DEF | Suspended | Jon Martín is serving a suspension for Yellow cards. | Martin is suspended with yellow cards | Apr 4 |
| Orri Oskarsson | F | Out indefinitely | None | Oskarsson is injured | May 3 |
| Ibai Basurco | MID | Suspended | Ibai Aguirre is serving a suspension for Yellow cards. | Basurco is suspended with yellow cards | Mar 30 |
| Y. Muto | A | Out indefinitely | Ankle/Foot Injury | Ankle/Foot Injury | Apr 26 |
| Matheus Pereira | MID | Out | Suspended | Suspended | Oct 30 |
| Etxeita | DEF | Out | Suspended | Suspended | Apr 23 |
| Anaitz Arbilla Zabala | DEF | Out | Suspended | Suspended | Mar 13 |
| Iván Ramis Barrios | DEF | Out indefinitely | Knee Injury | Knee Injury | Jul 24 |
| Francisco Manuel Rico Castro | MID | Out indefinitely | Knee Injury | Knee Injury | Jun 30 |
| Imanol Sarriegui Isasa | MID | Out | Hand Injury | Hand Injury | Mar 7 |
| Roberto Antonio Correa Silva | DEF | Out | Suspended | Suspended | Jan 8 |
| Paulo Oliveira | DEF | Out indefinitely | Hamstring | Hamstring | Dec 29 |
| G. Blanco | A | Out | Suspended | Suspended | Jan 10 |
| Javi Muñoz | MID | Out | Suspended | Suspended | Apr 1 |
| Enrique González Casín | A | Out indefinitely | Knock | Knock | Dec 23 |
| Peru Nolaskoain | DEF | Out | Suspended | Suspended | Jan 15 |
| Juan Berrocal | DEF | Out | Suspended | Suspended | Mar 7 |
| S. Okazaki | A | Out indefinitely | Hamstring | Hamstring | Nov 9 |
| Mikel Rico | MID | Out indefinitely | Virus | Virus | Nov 9 |
| Pablo Ínsua Blanco | DEF | Out | Suspended | Suspended | Apr 2 |
| Timor | MID | Out indefinitely | Knock | Knock | Dec 20 |
| Luisinho | DEF | Out indefinitely | Knee Injury | Knee Injury | May 22 |
| Juan Pablo Añor Acosta | MID | Out indefinitely | Hamstring | Hamstring | May 1 |
| Juan Pérez | GK | Out indefinitely | Arm/Elbow injury | Arm/Elbow injury | Dec 20 |
| Cristian Salvador | MID | Out | Suspended | Suspended | Jan 9 |
| Óscar Sielva | MID | Out | Suspended | Suspended | Feb 26 |
| Gerard Valentín | DEF | Out indefinitely | Hamstring | Hamstring | Dec 26 |
| Eugeni Valderrama | MID | Out indefinitely | Hamstring | Hamstring | May 22 |
| K. Nwakali | MID | Out indefinitely | Knock | Knock | Oct 18 |
| Pedro López Muñoz | DEF | Out indefinitely | Hamstring | Hamstring | Nov 9 |
| Juan Carlos | | Out | Virus | Virus | Jan 31 |
| Pablo Martínez | MID | Out | Suspended | Suspended | Oct 31 |
| Alexis Sanchez | F | Out indefinitely | Knee Injury | Knee Injury | Apr 21 |
| Cesar Azpilicueta | DEF | Out | Head Injury | Head Injury | Apr 11 |
| Lucien Agoume | MID | Out | Thigh Muscle Strain | Thigh Muscle Strain | Jan 19 |
| Chidera Ejuke | F | Out indefinitely | Knee Injury | Knee Injury | Apr 11 |
| Batista Mendy | MID | Out | Suspended | Suspended | Feb 19 |
| Tanguy Nianzou | DEF | Suspended | Tanguy Nianzou Kouassi is serving a suspension for Red card. | Nianzou is suspended with red card | Apr 5 |
| Jose Carmona | DEF | Suspended | José Ángel Carmona is serving a suspension for Yellow cards. | Carmona is suspended with yellow cards | Apr 5 |
| Alejandro Bergantiños García | MID | Out | Suspended | Suspended | Mar 11 |
| Javi Fuego | MID | Out | Suspended | Suspended | Mar 26 |
| Álvaro Vázquez | A | Out | Shoulder Injury | Shoulder Injury | Sep 12 |
| Jony | MID | Out | Suspended | Suspended | Feb 12 |
| Pichu Cuéllar | GK | Out indefinitely | Calf Muscle Strain | Calf Muscle Strain | Mar 1 |
| J. Babin | DEF | Out indefinitely | Thigh Muscle Strain | Thigh Muscle Strain | Feb 25 |
| Fernando Amorebieta Mardaras | DEF | Out indefinitely | Knock | Knock | Apr 3 |
| Pedro Díaz Fanjul | MID | Out | Suspended | Suspended | May 10 |
| Juan Rodríguez Martínez | DEF | Out indefinitely | Ankle/Foot Injury | Ankle/Foot Injury | May 1 |
| Sergio Álvarez Díaz | MID | Out | Suspended | Suspended | Feb 12 |
| José Ángel Valdés Díaz | DEF | Out indefinitely | Calf Muscle Strain | Calf Muscle Strain | Aug 24 |
| Jordi Calavera Espinach | DEF | Out indefinitely | Knock | Knock | Apr 22 |
| Pablo Pérez | MID | Out | Suspended | Suspended | May 7 |
| Molinero | DEF | Out | Suspended | Suspended | Jul 6 |
| Marc Valiente | DEF | Out | Suspended | Suspended | Nov 30 |
| J. Otero | A | Out | Suspended | Suspended | Dec 14 |
| Víctor Campuzano | A | Out indefinitely | Back Injury | Back Injury | Mar 1 |
| Vasyl Kravets | DEF | Out | Suspended | Suspended | Jan 23 |
| Fran Villalba | MID | Out | Suspended | Suspended | Apr 2 |
| José Marsà | DEF | Out | Suspended | Suspended | Apr 8 |
| Houboulang Mendes | DEF | Out | Knee Injury | Knee Injury | Jan 24 |
| Marko Marezi | F | Out indefinitely | Pubalgia | Pubalgia | Oct 29 |
| Mouctar Diakhaby | DEF | Out indefinitely | Mouctar Diakhaby is Unknown with Hamstring Injury. | Diakhaby is injured with hamstring | Jan 9 |
| Umar Sadiq | F | Out indefinitely | MCL Knee Ligament Injury | MCL Knee Ligament Injury | Apr 11 |
| Dimitri Foulquier | DEF | Out indefinitely | Hamstring | Hamstring | Jan 20 |
| Thierry Correia | DEF | Out indefinitely | Hamstring | Hamstring | Feb 27 |
| Jose Copete | DEF | Out | José Manuel Arias Copete is expected to return Late May 2026 from Meniscus injury. | Copete is out with knee | Feb 25 |
| Julen Agirrezabala | GK | Out for season | Julen Agirrezabala is Out for season with Hamstring Injury. | Agirrezabala is out for season with hamstring | Mar 5 |
| Ruben Iranzo | DEF | Out | Rubén Iranzo is expected to return Mid April 2026 from Knee injury. | Iranzo is out with knee | Mar 29 |
| Ayoze Perez | F | Out indefinitely | Illness | Illness | Dec 27 |
| Pau Cabanes | F | Out | Pau Cabanes is expected to return Late April 2026 from Cruciate ligament injury. | Cabanes is out with knee | Mar 29 |
Málaga CF
RC Deportivo La Coruna
SD Eibar
SD Huesca
Sporting Gijón
