Commanders vs Cardinals Picks, Odds, Predictions for NFL Week 4

Commanders vs Cardinals Picks, Odds, Predictions for NFL Week 4 article feature image
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Jayden Daniels #5 of the Washington Commanders (Photo by Cooper Neill/Getty Images)

Commanders vs. Cardinals may take the cake as most entertaining NFL Week 4 game Sunday. To sweeten the pot, we've recorded a sharp over/under pick in PRO between two high-octane offenses.

The game kicks off at 4:05 p.m. ET, and both teams enter with identical 1-2 records.

Commanders' QB Jayden Daniels and Cardinals' QB Kyler Murray, both known for their dual-threat capabilities, highlight what should be an exhilarating matchup.

Oddsmakers have set the spread at Cardinals -3.5 and the over/under at 49. The moneyline odds currently favor the Cardinals at -175 with the Commanders set at +150.

Commanders vs. Cardinals Odds, Picks, Predictions

Commanders Logo
Sunday, Sep 29
4:05 p.m. ET
FOX
Cardinals Logo
Commanders Odds
SpreadTotalMoneyline
+3.5
-120
49
-110o / -110u
+150
Cardinals Odds
SpreadTotalMoneyline
-3.5
+100
49
-110o / -110u
-178
Odds via Caesars. Get up-to-the-minute NFL odds here.
Caesars Logo
  • Commanders vs. Cardinals spread: Cardinals -3.5
  • Commanders vs. Cardinals over/under: 49
  • Commanders vs. Cardinals moneyline: Commanders +150, Cardinals -178

Spread

Murray and the Cardinals are -3.5 at home.

Over/Under

The over/under is set at 49 points. Both teams' over/unders have been set on the higher side this season.

Moneyline

The moneyline tabs the Cardinals as -178 favorites, while the Commanders are listed at +150 to pull off their second straight upset.

Player Prop

PRO Projections give Brian Robinson Jr. a 12% chance to score the first TD. His odds are +900, implying a 10% chance and offering a 2% edge on the Commanders RB to open the scoring.

PRO Projections recommend a 3.5% or better when tailing, so this one doesn't exactly meet the criteria.

Commanders vs. Cardinals Prediction

A couple Action PRO models matching on the over/under sparks an almost-too-obvious prediction.

Point Spread

Key betting insights indicate some contrarian data points.

We've tracked sharp money coming in on the Commanders, with professional action backing the away team.

Moreover, a pertinent PRO System—"Road Dog, Low Total After Bad Season"—supports the Commanders, boasting a 58% win rate and a 14% ROI.

Interestingly, big money bets align differently, with the Cardinals receiving 69% of the money but only 43% of the bets.

Total

The total over/under for this game is set at 49. Betting activity has shown sharp money overwhelmingly on the