Ohio State vs. Michigan St Odds & Betting Predictions - February 22, 2026

Ohio State at Michigan St

6:00 pm • CBS

Ohio State Buckeyes

21-12

60 - 66

Michigan State Spartans

25-7

MatchupOpenSpreadTotalMoneyline
Ohio State 21-12	+10.5	+10.5-103	o146.5-107	+450
Michigan St 25-7	u148.5	-10.5-116	u146.5-112	-625

Sunday 6:00 p.m.

February 22, 2026

Jack Breslin Students Events CenterEast Lansing

OSU +10.5-112

0.27u

Ohio State vs Michigan State: ML Parlay Piece
Ryan Minion•
Feb 22, 2026 UTC

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No props found

NCAAB Public Betting

Michigan St are 3-2 in their last 5 games.
Michigan St are 3-2 in their last 5 games against the spread
Michigan St are 7-4 in their road games against the spread
The totals have gone OVER in 4 of Michigan St' last 5 games
The totals have gone OVER in 9 of Michigan St' 21 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Michigan St	16-16	9-12	7-4	12-13	4-2
Ohio State	18-15	11-10	7-5	9-10	9-5

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Michigan St	15-17	9-12	6-5	12-13	3-3
Ohio State	16-17	12-9	4-8	11-8	5-9

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Michigan St	25-7	N/A	N/A	22-3	2-4
Ohio State	21-12	N/A	N/A	17-2	4-10

date	opponent	score	spread	over/under	moneyline
Feb 18th	UCLA	W 82-59	-8.5 W	O 139.5	MSU -425
Feb 14th	@WIS	L 71-92	-2 L	O 149.5	WIS -138
Feb 8th	ILL	W 85-82	-1.5 W	O 143	MSU -130
Feb 5th	@MINN	L 73-76	-8.5 L	O 135.5	MINN -450
Jan 31st	MICH	L 71-83	+2.5 L	O 148.5	MICH +116

Josh Ojianwuna
F
Ojianwuna is out with knee
Out

Taison Chatman
G
Chatman is questionable with undisclosed
Questionable
Myles Herro
G
Herro is out for season with redshirt
Out for Season

Kaleb Glenn
F
Glenn is out for season with knee
Out for Season
Divine Ugochukwu
G
Ugochukwu is out for season with foot
Out for Season

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Ohio State

Michigan St

23-52 (44%)

Field Goals

22-55 (40%)

10-17 (59%)

Free Throws

18-25 (72%)

4-22 (18%)

4-15 (27%)

Rebounds

Assists

Turnovers

Steals

Blocks

Fouls

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MatchupOverUnder
Ohio State 21-12	N/A	N/A
Michigan St 25-7	N/A	N/A

Ohio State vs. Michigan St Odds & Betting Predictions - February 22, 2026

Ohio State at Michigan St

Ohio State Buckeyes

Michigan State Spartans

Ohio State at Michigan St Odds

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Ohio State vs. Michigan St Previews & Analysis

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Michigan St

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Against the Spread (ATS) History

Over/Under History

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Last 5 Matchups

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Ohio State Injuries

Michigan St Injuries

Ohio State vs. Michigan St Odds Comparison

Ohio State at Michigan St Team Totals