Seminoles vs. Clemson Odds & Betting Predictions - February 21, 2026

Seminoles at Clemson

5:00 pm • The CW Network

Florida State Seminoles

18-15

70 - 65

Clemson Tigers

24-9

MatchupOpenSpreadTotalMoneyline
Seminoles 18-15	+9.5	+8.5-110	o145.5-110	+340
Clemson 24-9	u143.5	-8.5-110	u145.5-110	-440

Saturday 5:00 p.m.

February 21, 2026

Littlejohn ColiseumClemson

Florida State vs Clemson: Pace Mismatch Helps the Total
Christian Odjakjian•
Feb 21, 2026 UTC

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NCAAB Public Betting

Clemson are 4-1 in their last 5 games.
Clemson are 2-3 in their last 5 games against the spread
Clemson are 9-5 in their road games against the spread
The totals have gone OVER in 3 of Clemson' last 5 games
The totals have gone OVER in 7 of Clemson' 19 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Clemson	18-15	9-10	9-5	14-14	4-1
Seminoles	19-14	11-9	8-5	8-8	10-6

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Clemson	14-19	7-12	7-7	12-16	2-3
Seminoles	17-16	10-10	7-6	8-8	9-7

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Clemson	24-9	N/A	N/A	23-5	1-4
Seminoles	18-15	N/A	N/A	13-3	4-12

date	opponent	score	spread	over/under	moneyline
Feb 19th	@WAKE	L 77-85	-3.5 L	O 140	WAKE -190
Feb 14th	@DUKE	L 54-67	+13.5 W	U 134	DUKE +720
Feb 12th	VT	L 66-76	-8.5 L	O 138.5	VT -400
Feb 8th	@CAL	W 77-55	-4.5 W	U 139.5	CLEM -198
Feb 5th	@STAN	W 66-64	-3.5 L	U 138.5	CLEM -180

AJ Swinton
F
Swinton is out for season with knee
Out for Season

Xavier Osceola
G
Osceola is questionable with undisclosed
Questionable

Carter Welling
F
Welling is out with knee
Out
Zac Foster
G
Foster is out for season with knee
Out for Season

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Seminoles

Clemson

23-46 (50%)

Field Goals

21-56 (38%)

14-16 (88%)

Free Throws

13-15 (87%)

10-24 (42%)

10-33 (30%)

Rebounds

Assists

Turnovers

Steals

Blocks

Fouls

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MatchupOverUnder
Seminoles 18-15	N/A	N/A
Clemson 24-9	N/A	N/A

Seminoles vs. Clemson Odds & Betting Predictions - February 21, 2026

Seminoles at Clemson

Florida State Seminoles

Clemson Tigers

Seminoles at Clemson Odds

Spread, Total, Moneyline

Seminoles vs. Clemson Previews & Analysis

Florida State vs Clemson: Pace Mismatch Helps the Total

Prop Odds Comparison

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Seminoles vs. Clemson Public Betting Percentages

Seminoles

Public

Clemson

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Betting Trends

Matchup History

Against the Spread (ATS) History

Over/Under History

Straight-Up (ML) History

Last 5 Matchups

Seminoles vs. Clemson Injury Updates

Seminoles Injuries

Clemson Injuries

Seminoles vs. Clemson Odds Comparison

Seminoles at Clemson Team Totals