Cincinnati vs. Clemson Odds & Betting Predictions - December 21, 2025
Cincinnati at Clemson
8:00 pm • ESPNCincinnati at Clemson Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
 Cincinnati 18-15 | +6.5 | +4-110 | o140.5-108 | +154 |
 Clemson 24-10 | u137.5 | -4-110 | u140.5-110 | -185 |
Bon Secours Wellness ArenaGreenville
Cincinnati vs. Clemson Expert Picks
CTO
Last 30d: 23-27-0 (-2.7u)
CIN +5.5-105
0.95u
Cincinnati vs. Clemson Previews & Analysis
Prop Odds Comparison
Line Movement Tracker
Cincinnati vs. Clemson Public Betting Percentages
Betting Trends
- Clemson are 3-2 in their last 5 games.
- Clemson are 1-4 in their last 5 games against the spread
- Clemson are 9-6 in their road games against the spread
- The totals have gone OVER in 2 of Clemson' last 5 games
- The totals have gone OVER in 7 of Clemson' 19 last games at home
Matchup History
Against the Spread (ATS) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 18-16 | 9-10 | 9-6 | 14-14 | 4-2 |
| 14-19 | 10-10 | 4-9 | 10-9 | 4-9 |
Over/Under History
| overall | home o/u | away o/u | favorite o/u | underdog o/u | |
|---|---|---|---|---|---|
| 14-20 | 7-12 | 7-8 | 12-16 | 2-4 |
| 12-20-1 | 7-12-1 | 5-8 | 7-11-1 | 4-9 |
Straight-Up (ML) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
| 24-10 | N/A | N/A | 23-5 | 1-5 |
| 18-15 | N/A | N/A | 15-4 | 2-11 |
Last 5 Matchups
Cincinnati vs. Clemson Injury Updates
Cincinnati Injuries
- Jalen HaynesF
Haynes is out for season with lower body
Out for Season
Clemson Injuries
Team Stats
22-58 (38%)
Field Goals
24-50 (48%)
11-15 (73%)
Free Throws
10-14 (71%)
10-25 (40%)
3P
10-20 (50%)
33
Rebounds
23
9
Assists
15
12
Turnovers
12
5
Steals
6
4
Blocks
1
13
Fouls
12
Cincinnati vs. Clemson Odds Comparison
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Cincinnati at Clemson Team Totals
MatchupOverUnder | ||
|---|---|---|
Cincinnati 18-15 | N/A | N/A |
Clemson 24-10 | N/A | N/A |