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Rangers vs Astros Prediction, Pick, Odds for Wednesday, September 17

Rangers vs Astros Prediction, Pick, Odds for Wednesday, September 17 article feature image
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Photo by Brad Penner-Imagn Images. Pictured: Jacob deGrom

The Houston Astros host the Texas Rangers on September 17, 2025. First pitch from Daikin Park is scheduled for 8:10 p.m. EDT; the game will be broadcast on SCHN.

The Rangers lost the first two games of this series and will have ace Jacob deGrom on the hill today to avoid the sweep.

Find my MLB betting preview and Rangers vs Astros prediction below, as well as probable pitchers, betting trends, injury reports and more.

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My Rangers vs Astros Prediction

  • Rangers vs Astros pick: Under 7.5 (-115)

My Rangers vs Astros best bet is Under 7.5 total runs in this game. Make sure to find the best odds by checking our live MLB odds page.


Rangers vs Astros Odds

Rangers Logo
Wednesday, Sep 17
8:10 p.m. ET
SCHN
Astros Logo
Rangers Odds
SpreadTotalMoneyline
-1.5
+130
7.5
-105o / -115u
-130
Astros Odds
SpreadTotalMoneyline
+1.5
-155
7.5
-105o / -115u
+110
Odds via bet365. Get up-to-the-minute MLB odds here.
bet365 Logo

Rangers vs Astros Projected Starting Pitchers

RHP Jacob deGrom (TEX)StatRHP Cristian Javier (HOU)
12-7W-L1-3
3.4fWAR (FanGraphs)0.4
2.82 / 3.32ERA / xERA4.78 / 3.36
3.59 / 3.37FIP / xFIP4.25 / 5.05
0.92WHIP1.29
21.6K-BB%11.5
39.1GB%28.8
111Stuff+94
106Location+94

Rangers vs Astros Preview

The Rangers are on a minor slump, producing just 13 runs in their past four games for an average of 3.25 per contest.

In fact, both teams are in the bottom half in wRC+ this month: Texas ranks 22nd while Houston sits at the 17th spot.

On top of that, we have Jacob deGrom starting for the Rangers. The two-time Cy Young winner has a 2.82 ERA this season, and he has faced the Astros three times this year, leaving them scoreless in their first matchup through eight complete innings, and allowing two and three earned runs the next two games against them.

Cristian Javier will take the mound for the Astros, and he has an excellent home ERA of 3.44. Plus, both bullpens are solid: the Rangers rank fifth in ERA with 3.60, and the Astros are 11th with 3.76 this season.

Our Bet Labs recommendation for this contest is the under.

MLB Icon
Evan Abrams – Contrarian Unders for Winning Teams, Later in Series
the game is played during the Regular or Postseason season
betting on the Under
the home team's win percentage is between 51% and 100%
the visitor team's win percentage is between 51% and 100%
the over/under % is between 0% and 35%
the series game # is between 2 and 100
$13,418
WON
1376-1174-110
RECORD
54%
WIN%

This system targets unders in MLB series games (Game 2 or later) where both teams have winning records, suggesting quality pitching and competitive matchups.

However, public betting leans toward the over — likely expecting fireworks between top teams — which creates contrarian value on the under.

By capitalizing on low public support for the under (≤35%), the strategy fades public perception in favor of market inefficiencies, especially when bettors overestimate offensive output late in a series.

Pick: Under 7.5 (-115, bet365)


Rangers vs Astros Betting Trends


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