Rays vs Orioles Prediction, Odds, Picks, MLB Betting Guide

Rays vs Orioles Prediction, Odds, Picks, MLB Betting Guide article feature image
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Credit: Imagn Images. Pictured: Tampa Bay Rays IF Brandon Lowe.

The Baltimore Orioles host the Tampa Bay Rays on Friday, June 27, 2025. First pitch from Oriole Park at Camden Yards is scheduled for 7:05 p.m. ET; the game will be broadcast on Apple TV+.

The Rays enter as -130 favorites on the moneyline, while the Orioles come in at +110 to pull off the upset. The over/under, meanwhile, sits at 8.5 total runs.

Read our Rays vs Orioles predictions and MLB pick for this American League East clash on Friday, June 27 below.

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Rays vs Orioles Prediction, Picks

  • Rays vs Orioles Pick: Rays F5 ML (-135 · BetMGM)

My Orioles vs. Rays best bet is on Tampa's F5 ML. Make sure to find the best odds by checking our live MLB odds page.


Rays vs Orioles Odds, Line, Spread

Rays Logo
Friday, June 27
7:05 p.m. ET
Apple TV+
Orioles Logo
Rays Odds
Run LineTotalMoneyline
-1.5
+126
8.5
-114o / -106u
-130
Orioles Odds
Run LineTotalMoneyline
+1.5
-152
8.5
-114o / -106u
+110
Odds via FanDuel. Get up-to-the-minute MLB odds here.
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Rays vs Orioles Pick, Best Bets

Ryan Pepiot had an uneven April, but he's been rolling recently.

He has a 2.37 ERA across 10 starts since the beginning of May, and he hasn’t allowed more than three earned runs in a single start since April 15th. This is the first season he’s on track to post above-average Stuff+ and Location+ marks.

This might be the best version of Pepiot we’ve seen.

Conversely, Tomoyuki Sugano's weak underlying metrics are finally catching up to him.

He's been knocked around this month, posting a 4.58 ERA across four starts. Sugano's xERA (4.98) and SIERA (4.60) are still more than a run higher than his actual ERA (3.55). That mark will likely continue to rise.

The Rays have been one of the hottest offenses in the league. They rank among the top three MLB lineups in OPS, wOBA and wRC+ against right-handed pitching over the past month.

Meanwhile, Baltimore has been closer to a below-average offense during the same stretch.

Pick: Rays F5 ML (-135 · BetMGM)

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