The Houston Astros host the Philadelphia Phillies on Thursday, June 26, 2025. First pitch from Daikin Park is scheduled for 2:10 p.m. ET; the game will be broadcast on SCHN and MLB.TV.
The Astros enter as -150 favorites on the moneyline, while the Phillies sit at +123 to pull off the upset. The over/under, meanwhile, sits at 7.
Read our Phillies vs Astros prediction and MLB same-game parlay picks below.
Philadelphia Phillies vs Houston Astros Prediction, Picks
- Hunter Brown Over 6.5 Ks
- Astros ML
Parlay odds: +178 (DraftKings)
Phillies vs Astros Odds, Line, Spread
| Phillies Odds | ||
|---|---|---|
| Run Line | Over/Under | Moneyline |
+1.5 -197 | 7 -120o / -101u | +123 |
| Astros Odds | ||
|---|---|---|
| Run Line | Over/Under | Moneyline |
-1.5 +160 | 7 -120o / -101u | -150 |
Phillies vs Astros Pitchers
| LHP Cristopher Sanchez (PHI) | Stat | RHP Hunter Brown (HOU) |
|---|---|---|
| 6-2 | W-L | 8-3 |
| 2.0 | fWAR (FanGraphs) | 2.5 |
| 2.87 / 3.31 | ERA / xERA | 1.88 / 3.04 |
| 3.14 / 3.13 | FIP / xFIP | 2.84 / 2.83 |
| 1.19 | WHIP | 0.92 |
| 17.6% | K-BB% | 23.5% |
| 55.7% | GB% | 46.8% |
| 113 | Stuff+ | 110 |
| 95 | Location+ | 98 |
Phillies vs Astros MLB Betting Preview
Astros Player Prop: Hunter Brown Over 6.5 Strikeouts
I'm backing young ace Hunter Brown to stay hot as he takes the mound.
Brown has been excellent all season. He sports a 1.88 ERA, 109 strikeouts, and an 8-3 record. If it weren’t for Skubal’s dominance, Brown could be a sneaky Cy Young candidate this season. He also boasts an outstanding whiff rate.
Specifically, I'm backing him to eclipse 6.5 strikeouts today against the Phillies.
The Phillies’ bats have struggled in Houston, with zero runs in 18 innings so far.
It won't get any easier against Brown.
Moneyline Pick: Astros ML
In addition, I'm betting on the Astros to complete the sweep.
Houston has been playing good baseball, going 4-1 over its past five games.
At home with its ace on the mound, you have to back the hot team. I expect the Astros will pull out a low-scoring victory on Thursday.
Phillies vs Astros MLB Same-Game Parlay Picks
- Hunter Brown Over 6.5 Ks
- Astros ML
Parlay odds: +178 (DraftKings)
