The Yankees (1-0) and Giants (0-1) continue their MLB interleague series today. First pitch from Oracle Park is scheduled for 4:35 p.m. ET. Yankees vs Giants will broadcast on YES and NBC Sports Bay Area.
Yankees vs Giants odds list the Yankees as -136 moneyline favorites and Giants as +113 underdogs. The game total is 8.5 (-108o / -112u). The Yankees are +123 to cover the run line (-1.5); the Giants are -149 to cover (+1.5) .
Continue below to find my Yankees vs Giants prediction, plus the latest MLB odds, probable pitchers, betting trends, viewing information, weather and more.
New York Yankees vs San Francisco Giants Prediction & Picks
- Yankees vs Giants Pick: Over 7.5
My Yankees vs Giants best bet is on the game total to go over. Make sure to find the best odds by checking our live MLB odds page.
Yankees vs Giants Odds, Spread, Over/Under, Moneyline
| Yankees Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +123 | 8.5 -108o / -112u | -136 |
| Giants Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -149 | 8.5 -108o / -112u | +113 |
Yankees vs Giants Probable Pitchers
| RHP Cam Schlittler (NYY) | Stat | LHP Robbie Ray (SF) |
|---|---|---|
| Season Debut | W-L | Season Debut |
| – | fWAR (FanGraphs) | – |
| – | ERA /xERA | – |
| – | FIP / xFIP | – |
| – | WHIP | – |
| – | K-BB% | – |
| – | GB% | – |
| – | Stuff+ | – |
| – | Location+ | – |
Yankees vs Giants Preview, Predictions
Yankees Preview
The betting public was all hyped up and ready to get some home run bets in for the Yanks' season's first game. And what did Aaron Judge, Rafael Devers, and company deliver? A goose egg in homers.
But this is a much different pairing of pitchers. Game one featured two of the game's elite home run suppressors — Max Fried and Logan Webb. Game two has no such thing. We've got Robbie Ray (47% FB%, 1.76 HR/9 in 2025) hosting Cam Schlittler (38% FB%, 0.99 HR/9 in 2025).
Ray is a known commodity, albeit an old one. And Schlittler is one of the new guys on the block. Ray has nine years on his counterpart in this one, and they throw with opposite hands. But they're both guys with histories of strikeouts, walks, and home runs allowed. The "three true outcome" pitcher, if you will.
Both guys throw a bunch of four-seam fastballs (Ray around 94mph, Schlittler around 98mph) with a pretty solid breaker behind it (Ray a slider, Schlittler a curve). So it's two very different pitchers who still attack and get the ball in play in basically the same way. And that is where we focus our attention.
Giants Preview
On the Giants' starting pitching front, we have basically the opposite of what we had on opening night.
Fried and Webb brought elite walk rates and higher ground ball rates to the table, without a ton of strikeout upside. The two arms going in this one bring big strikeout potential with spotty command and a bunch of balls allowed to be hit in the air.
As for the fantasy — which I actively keep an eye on every year — everything I looked at with these two pointed to a massive fade of both guys.
I don't believe I have a single share of either one. Yesterday was a great example of how unreliable starting pitching can be early in the year. I'm betting on some offense in this game.
Yankees vs Giants Prediction, Over/Under Betting Analysis
It's a very interesting "compare and contrast" with these two SPs. I feel like you could write a book about it. In another similarity, I think the public will hold too high an opinion of each guy, albeit for different reasons.
Robbie Ray threw 182 1/3 innings last year, and that followed a completely lost season after a Tommy John that cost him his 2024 season. It was an impressive volume feat. But what you might not have noticed is that he lost a good bit of strikeout ability. His 24.6% K% last year came in four points below his career average.
The thing a lot of people remember about Cam Schlittler is the dominant outing he had in the postseason last year against the Red Sox. He threw eight scoreless with 12 strikeouts under the brightest lights of a postseason elimination game. What we don't remember as much is the 10.2% BB% he posted in his Major League time, along with the dangerous game he plays, allowing fly balls as we've already talked about.
Speaking of short memories, all of the talk is negative on Aaron Judge right now. A lackluster WBC and then a huge 0/5 with four strikeouts in the season's first game. By the way, I don't believe the books are going to downgrade the guy in any way, but the public's money just might push toward this 'anti-Judge' side if this trend continues.
It's a great spot for him against Robbie Ray. Judge is one of the best to ever hold a baseball bat. I'd like to be on his side when the crowd starts to lean against him.
The books are dragging their feet on the walk lines, so I can't say it for sure — but I'll be very curious to see if we can get a reasonable price on over 1.5 walks for either guy, particularly Schlittler against this patient Giants lineup.
Pick: Over 7.5 Runs (-115)
Yankees vs Giants Betting Trends
Yankees vs Giants Viewing Info: Channel, Start Time, Streaming
| Location: | Oracle Park in San Francisco, Calif. |
| Date: | Friday, March 27 |
| Time: | 4:35 p.m. ET |
| TV / Streaming Options: | YES; NBC Sports Bay Area; MLB.TV |
Yankees vs Giants Key Injuries
Yankees Injuries
Gerrit Cole (15-day IL; Tommy John surgery)
Carlos Rodon (15-day IL; left elbow surgery)
Anthony Volpe (10-day IL; left shoulder surgery)
Giants Injuries
Hayden Birdsong (60-day IL; Tommy John surgery)
Joel Peguero (15-day IL; left hamstring strain)
