The St. Louis Cardinals host the Seattle Mariners on April 24, 2026. First pitch from Busch Stadium is scheduled for 8:15 p.m. EDT. The game will be broadcast on CARD.
The Mariners are favored by -147 on the moneyline and by -1.5 on the run line. The Cardinals are +125 on the moneyline and +1.5 on the run line. The total is set at 8 runs.
Find my MLB picks and Mariners vs Cardinals prediction below, as well as probable pitchers, weather report, and more.
- Mariners vs Cardinals Pick: Under 8
My Mariners vs Cardinals best bet is on the Under. Make sure to find the best odds by checking our live MLB odds page.
Mariners vs Cardinals Odds
| Mariners Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 -140 | 8 -102o / -118u | -147 |
| Cardinals Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 +115 | 8 -102o / -118u | +125 |
- Mariners vs Cardinals moneyline: Mariners -147, Cardinals +125
- Mariners vs Cardinals over/under: 8 (-102o / -118u)
- Mariners vs Cardinals spread: Mariners -1.5 (+115), Cardinals +1.5 (-140)
Mariners vs Cardinals Probable Pitchers
| George Kirby, SEA | Stat | Andre Pallante, STL |
|---|---|---|
| 3-2 | W-L | 2-1 |
| 0.4 | fWAR (FanGraphs) | 0.0 |
| 2.97 / 2.91 | ERA / xERA | 4.05 / 5.41 |
| 3.90 / 3.51 | FIP / xFIP | 5.20 / 5.43 |
| 14.7% | K-BB% | 1.1% |
| 60.2% | GB% | 51.5% |
| .258 | BABIP | .250 |
| 98 | Stuff+ | 95 |
| 114 | Location+ | 91 |
Mariners vs Cardinals MLB Betting Preview
The Mariners arrive in St. Louis as a difficult team for the public to pin down. While they often find themselves in high-scoring affairs, there is a distinct "bounce-back" trend following offensive outbursts.
This season, every time a Mariners game has exceeded 8 runs, the following game has gone under 8 runs five separate times. Coming off a 5-4 win against the Athletics on Wednesday, history suggests the Seattle bats (or its opponents') are due for a quiet night.
Taking the mound for Seattle is George Kirby, whose underlying metrics are elite. Kirby enters with a 2.97 ERA, but his 2.91 xERA (expected ERA) proves that his success is no fluke. Kirby’s ability to command the zone and limit walks makes him the perfect anchor for a nighttime Under.
The Cardinals have been a reliable 'under' team recently.
In their last three outings, St. Louis games have either pushed at exactly 8 runs or finished comfortably under. While the public might see the Cardinals' home-field advantage as an offensive boost, the system notes that their recent home scoring has been modestly over, which often leads to an inflated total that savvy bettors can exploit.
Andre Pallante gets the start for the Redbirds. While his 4.05 ERA is respectable, his 5.41 xERA suggests he has benefited from some luck and solid defense.
However, in the context of this system, the "Recency Bias" of Pallante's surface-level success helps keep the total high enough for us to extract value on the Under.

Mariners vs Cardinals Pick, Betting Analysis
Everything points to a pitcher's duel in St. Louis.
Kirby’s elite xERA should neutralize a Cardinals lineup that has already been trending toward the Under. On the other side, the Mariners’ historical trend of following high-scoring games with defensive battles provides a high-probability "correction" tonight.
Forecasts call for an overcast, 70-degree night, with 10 mph gusts. Given that the wind is offering neutral impact and the temperature is sitting in a range that doesn't favor the long ball, the Under 8 is the professional play.
Pick: Under 8 (-115, FanDuel)

































