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Angels vs Brewers Prediction, Pick, Odds for Wednesday, September 17

Angels vs Brewers Prediction, Pick, Odds for Wednesday, September 17 article feature image
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Kevin Sousa-Imagn Images. Pictured: Brandon Woodruff.

The Milwaukee Brewers host the Los Angeles Angels on September 17, 2025. First pitch from American Family Field is scheduled for 7:40 p.m. EDT; the game will be broadcast on FDSW.

Find my MLB betting preview and Angels vs Brewers prediction below, as well as probable pitchers, betting trends, injury reports and more.

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My Angels vs Brewers Prediction

  • Angels vs Brewers picks: Brandon Woodruff Over 7.5 Strikeouts

My Angels vs Brewers best bet is for Milwaukee's pitcher to land eight or more strikeouts tonight. Make sure to find the best odds by checking our live MLB odds page.


Angels vs Brewers Odds

Angels Logo
September 17, 2025
7:40 p.m. EDT
FDSW
Brewers Logo
Angels Odds
SpreadTotalMoneyline
+1.5
+105
7.5
-112o / -107u
+175
Brewers Odds
SpreadTotalMoneyline
-1.5
-125
7.5
-112o / -107u
-215
Odds via bet365. Get up-to-the-minute MLB odds here.
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Angels vs Brewers Projected Starting Pitchers

RHP Jose Soriano (LAA)StatRHP Brandon Woodruff (MIL)
10-10W-L6-2
3.0fWAR (FanGraphs)1.6
4.13 / 4.10ERA /xERA3.32 / 2.27
3.72 / 3.51FIP / xFIP3.27 / 3.41
1.38WHIP0.96
10.6%K-BB%25.1%
65.4%GB%35.1%
95Stuff+96
111Location+106

Alex Kolodziej's Angels vs Brewers Prediction, Betting Analysis

For Wednesday’s Brewers vs. Angels matchup, our top pick centers on starting pitcher Brandon Woodruff landing over 7.5 strikeouts. While that total might seem ambitious at first glance, PRO Projections strongly supports the over in this spot.

According to PRO’s calculations, Woodruff is expected to record 8.4 strikeouts in Wednesday’s game, which translates to a 5.4% betting edge.

Woodruff’s recent form adds further confidence: he tallied 8 strikeouts in his previous outing and has surpassed this benchmark in two of his last three starts. Also, Woodruff has a high ceiling in this category, posting a 10-strikeout game earlier this year.

The Angels lineup provides additional support for the over. This season, they rank worst in the majors for strikeouts, averaging 10 strikeouts per game as a team. That number increased to 10.3 on the road.

Woodruff also benefits from pitching at home in Miller Park, which Statcast ranks as the second-best park for pitcher strikeouts this year.

Pick: Brandon Woodruff Over 7.5 Strikeouts


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Author Profile
About the Author

Alex began his career as a freelancer before becoming a columnist, reporter, and breaking news writer for FanRag Sports, and later the leading gambling writer at theScore. He joined the Action Network as a senior news editor, handling breaking news and the sports betting market's reactions. Alex also works on Action Network’s PRO projections, transforming subscription-based models into user-friendly content.

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