The Minnesota Twins host the Houston Astros on April 3, 2025. First pitch from Target Field is scheduled for 4:10 p.m. EDT; the game will be broadcast on MNNT.
Astros vs Twins odds have the Twins as -125 moneyline favorites and the Astros as +105 underdogs. The over/under is 7 total runs. Minnesota is +170 to cover the run line (-1.5) and Houston is -205 to cover (+1.5).
Find my MLB betting preview and Astros vs Twins prediction below, as well as probable pitchers, betting trends, injury reports and more.
My Astros vs Twins Predictions
- Astros vs Twins picks: Astros +1.5, Joe Ryan 5 Ks, Hunter Brown 6 Ks and under 10.5 total runs (+212)
My Astros vs Twins best bets are Astros +1.5, Joe Ryan to record 5+ Strikeouts, Hunter Brown to record 6+ Strikeouts and under 10.5 total runs. Make sure to find the best odds by checking our live MLB odds page.
Astros vs Twins Odds, Spread, Over/Under
| Astros Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -205 | 7 -125o / 105u | +105 |
| Twins Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +170 | 7 -125o / 105u | -125 |
- Astros vs Twins Moneyline: Astros +105, Twins -125
- Astros vs Twins Total: 7 (-125o / +105u)
- Astros vs Twins Run Line: Astros +1.5 (-205), Twins -1.5 (+170)
- Astros vs Twins Best Bets: Astros +1.5; Joe Ryan 5 Ks; Hunter Brown 6 Ks; Under 10.5
Astros vs Twins Preview, Prediction, Betting Analysis
The game between the Astros and Twins is set for a blisteringly cold day in Minnesota. With winds swirling, the true temperature around first pitch will be around 30 degrees. The ball will not be going very far in today’s matchup, so we’re backing an alt under.
Today’s matchup also features two young, star pitchers. In his season debut, Hunter Brown pitched a gem, recording seven strikeouts. His arm looks like it’s in prime condition already this season and we expect him to also throw at least six innings today. With the Twins having one of the weaker offenses in MLB this season, over 5.5 Ks is a must-play in this parlay.
In addition, we have opted to take Joe Ryan for five strikeouts today. He boasted a strong start to the season, throwing 81 pitches with five strikeouts. Today, he will be facing a struggling Astros offense that struck out 14 times in their last game, and an average of over 10 in their past three. Ryan will look to pitch deep into this one, and we predict he’ll go at least six innings.
In a low0scoring, cold game, we are taking the Astros +1.5 to wrap the same-game parlay. After getting swept by the Giants, the Astros will look to bounce back from their slow start to the season. Even if the Astros don’t win, we expect the game to be low scoring enough that one run may be the difference.
Astros vs Twins Same-Game Parlay
- Astros +1.5
- Joe Ryan 5+ Strikeouts
- Hunter Brown 6+ Strikeouts
- Under 10.5 Total Runs
Parlay odds: +270 (Fanatics)
