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Home Run Picks Today: MLB Bets for Twins-Blue Jays, Astros-Mariners, More for April 11

Home Run Picks Today: MLB Bets for Twins-Blue Jays, Astros-Mariners, More for April 11 article feature image
11 min read
Credit:

Mar 30, 2026; Houston, Texas, USA; Houston Astros designated hitter Yordan Alvarez (44) hits a two-run home run during the third inning against the Boston Red Sox at Daikin Park. Mandatory Credit: Troy Taormina-Imagn Images

It's a massive Saturday, so you know I've got some bangers.

Read on for my Home Run Picks Today and MLB best bets for Saturday, April 11.

Home Run Picks Today

GameTime (ET)Pick
Minnesota Twins LogoToronto Blue Jays Logo
3:07 PM
Minnesota Twins LogoToronto Blue Jays Logo
3:07 PM
Minnesota Twins LogoToronto Blue Jays Logo
3:07 PM
Chicago White Sox LogoKansas City Royals Logo
4:10 PM
Chicago White Sox LogoKansas City Royals Logo
4:10 PM
San Francisco Giants LogoBaltimore Orioles Logo
7:15 PM
Texas Rangers LogoLos Angeles Dodgers Logo
9:10 PM
Texas Rangers LogoLos Angeles Dodgers Logo
9:10 PM
Houston Astros LogoSeattle Mariners Logo
9:40 PM
Specific betting recommendations come from the sportsbook offering preferred odds as of writing. Always shop for the best price using our MLB Odds page, which automatically surfaces the best lines for every game.
Playbook

Editor's Note: A home run parlay is not the author's formal recommendation. These home run picks have value as straight bets.

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Twins vs Blue Jays Home Run Picks

Minnesota Twins Logo
Saturday, April 11
3:07 PM ET
MLB.TV
Toronto Blue Jays Logo
Daulton Varsho Home Run
FanDuel Logo

Varsho is in a great spot, and the odds are far too high.

Joe Ryan is a massive fly-ball pitcher and grades out as a great matchup for lefty power.

The ballpark is a plus for power, and Varsho is an above-average home run hitter.

I have the true odds on Varsho around +375.

Pick: Daulton Varsho Home Run



Twins vs Blue Jays Home Run Picks

Minnesota Twins Logo
Saturday, April 11
3:07 PM ET
MLB.TV
Toronto Blue Jays Logo
Kazuma Okamoto Home Run
FanDuel Logo

I've been hammering Okamoto all season, but this is a spot where he is greatly underpriced.

Joe Ryan is a massive fly-ball pitcher and has been crushed by righty power in his career, allowing 1.5 HR/9.

The ballpark is a plus for power, and I have the true odds around +500 for Okamoto.

Pick: Kazuma Okamoto Home Run



Twins vs Blue Jays Home Run Predictions

Minnesota Twins Logo
Saturday, April 11
3:07 PM ET
MLB.TV
Toronto Blue Jays Logo
Vladimir Guerrero Home Run
FanDuel Logo

I know that Vlad hasn't been the same HR hitter over the last few seasons, but he's still been hitting the ball hard, and he gets a great spot here.

The ballpark is a plus for power, and Joe Ryan is a massive fly-ball pitcher who has allowed 1.5 HR/9 to righties in his career.

Vlad just needs someone who forces him to get the ball up in the air, and Ryan is just that type of guy.

I have the true odds on Vlad around +400.

Pick: Vladimir Guerrero Home Run



White Sox vs Royals Home Run Picks

Chicago White Sox Logo
Saturday, April 11
4:10 PM ET
MLB.TV
Kansas City Royals Logo
Bobby Witt Jr. Home Run
FanDuel Logo

Witt gets a decent spot today, and the odds are too high.

Erick Fedde grades out as an above-average matchup for righty power.

The ballpark is drastically better with the fences moved in, and the weather isn't bad for hitting, with temps in the low 70s and cross-field winds.

I have the true odds on Witt around +450.

Pick: Bobby Witt Jr. Home Run



White Sox vs Royals Home Run Picks Today

Chicago White Sox Logo
Saturday, April 11
4:10 PM ET
MLB.TV
Kansas City Royals Logo
Carter Jensen Home Run
FanDuel Logo

Jensen has been absolutely fantastic this season. He has 4 bombs in 13 games.

The spot here is a good one versus Erick Fedde, who grades out as an above-average matchup for lefty power.

The ballpark is now above average for offense with the fences moved in, and the weather is decent for hitting, with temps in the low 70s and cross-field winds.

I have the true odds on Jensen around +500.

Pick: Carter Jensen Home Run



Giants vs Orioles Home Run Picks

San Francisco Giants Logo
Saturday, April 11
7:15 PM ET
MLB.TV
Baltimore Orioles Logo
Rafael Devers Home Run
FanDuel Logo

This is by far my favorite bet of the day.

Chris Bassitt has been a gas can for lefty power for years, and he has massive splits.

The ballpark is a huge upgrade for Devers, and it has been a very hitter-friendly park for lefty bats for several years.

The weather is about average, and I have Devers at around +340.

Pick: Rafael Devers Home Run



Rangers vs Dodgers Home Run Picks Today

Texas Rangers Logo
Saturday, April 11
9:10 PM ET
MLB.TV
Los Angeles Dodgers Logo
Corey Seager Home Run
FanDuel Logo

We don't have a huge sample size of Emmet Sheehan in the majors, but he has allowed a massive 1.55 HR/9 to lefties and grades out as an above-average matchup for lefty power.

The weather in LA is good for hitting, with temps in the mid-60s and wind blowing out at 10 MPH.

Seager has been great this season, and I have the true odds around +300.

Pick: Corey Seager Home Run



Rangers vs Dodgers Home Run Picks Today

Texas Rangers Logo
Saturday, April 11
9:10 PM ET
MLB.TV
Los Angeles Dodgers Logo
Jake Burger Home Run
FanDuel Logo

Burger gets a good spot against Emmet Sheehan, who grades out as an above-average matchup for righty power.

The weather over in LA is good for hitting, with the wind blowing out at 10 MPH.

Burger had a rough season last year, but he's been hitting the ball hard this season and has a ton of power.

I have the true odds on Burger around +400.

Pick: Jake Burger Home Run



Astros vs Mariners Home Run Picks

Houston Astros Logo
Saturday, April 11
9:40 PM ET
MLB.TV
Seattle Mariners Logo
Yordan Alvarez Home Run
FanDuel Logo

Alvarez has been one of the best hitters in the league this season, and the odds are too high on him tonight.

The matchup versus Luis Castillo is a plus one for lefty power.

The ballpark is below average for HRs, but the odds more than make up for it.

I have the true odds under +300.

Pick: Yordan Alvarez Home Run



Author Profile
About the Author
Grant NeifferVerified Action Expert

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