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Guardians vs Mariners Prediction, Odds: Sunday Night Baseball Picks for Tonight’s Game on March 29, 2026

Guardians vs Mariners Prediction, Odds: Sunday Night Baseball Picks for Tonight’s Game on March 29, 2026 article feature image
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Stephen Brashear-Imagn Images. Pictured: Seattle catcher Cal Raleigh

Starting soon
Odds Updating Soon
Matchup - 3/29 11:20pm UTCSpreadTotalMoneyline
+1.5-175
o7.5-105
+124
-1.5+145
u7.5-115
-146

The Seattle Mariners (1-2) host the Cleveland Guardians (2-1) on March 29, 2026, for Sunday Night Baseball. First pitch from T-Mobile Park is scheduled for 7:20 p.m. ET. The game will be broadcast on Peacock.

The Mariners are favored by -144 on the moneyline and by -1.5 (+146) on the run line. The Guardians are +122 on the moneyline and +1.5 (-176) on the run line. The total is set at 7.5 runs (-118 / -104).

Find my MLB picks and Guardians vs Mariners prediction below, as well as probable pitchers, weather report, and more.


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Guardians vs Mariners Prediction & Pick

  • Guardians vs Mariners Pick: Over 7.5 (-112)

My Guardians vs Mariners best bet is Over 7.5 total runs in this game. Make sure to find the best odds by checking our live MLB odds page.


Guardians vs Mariners Odds, MLB Over/Under

Guardians Logo
Sunday, Mar 29
7:20 p.m. ET
Peacock
Mariners Logo
Guardians Odds
SpreadTotalMoneyline
+1.5
-176
7.5
-118o / -104u
+122
Mariners Odds
SpreadTotalMoneyline
-1.5
+146
7.5
-118o / -104u
-144
Odds via FanDuel. Get up-to-the-minute MLB odds here.
FanDuel Logo
  • Guardians vs Mariners spread: Guardians +1.5 (-176), Mariners -1.5 (+146)
  • Guardians vs Mariners over/under: Over 7.5 (-118), Under 7.5 (-104)
  • Guardians vs Mariners moneyline: Guardians +122, Mariners -144

Guardians vs Mariners Polymarket Odds

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Guardians vs Mariners Probable Starters

RHP Slade Cecconi (CLE)2025 StatsRHP Emerson Hancock (SEA)
7-7W-L4-5
0.7fWAR (FanGraphs)0.0
4.30 / 5.00ERA / xERA4.90 / 5.52
4.64 / 4.09FIP / xFIP5.08 / 4.61
1.19WHIP1.38
14.1K-BB%8.6
41.3GB%43.0
93Stuff+90
105Location+100

Sunday Night Baseball: Guardians vs Mariners Game Preview

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Cleveland Guardians Betting Preview

The Guardians were able to pull through in extra innings after Cade Smith blew the save in the ninth, winning 6-5 thanks to rookie sensation Chase DeLauter's fourth home run of the season.

Cleveland will try to take three of four, which would be an impressive way to start the year, since it's a road series against a World Series contender.

Right-hander Slade Cecconi is on the mound for the Guardians. He struggled last season with a 5.00 xERA, but he's looked sharp this spring, including four scoreless innings against the Diamondbacks in his final tune-up.

With Cecconi's underwhelming stuff (93 Stuff+) and lack of strikeout ability (20.0 K%), he could have a tough time against a Mariners lineup that is stacked with power hitters like Julio Rodriguez and Cal Raleigh.

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Seattle Mariners Betting Preview

The Mariners will look to salvage the split in this four-game series against the Guardians. It's been disappointing because both losses were by two runs or fewer.

The M's need their superstar Cal Raleigh to get on track, as he's 1-for-8 with nine strikeouts so far. Perhaps in facing a righty who pitches to contact in Cecconi, Big Dumper can find his groove.

Like Cleveland, Seattle is sending out a pitcher who struggled last year in Emerson Hancock. This is a righty who gave up a 5.52 xERA and struggled to rack up strikeouts (16.6 K%).

That's bad news against the red-hot Guardians bats like DeLauter, not to mention perennial All-Star Jose Ramirez.

It also doesn't help that Hancock struggled in his last spring outing, giving up three runs on eight hits in 3.2 innings against the Brewers.


How To Make My Guardians vs Mariners Picks

Both Cecconi and Hancock are unlikely to go more than five innings in this game. That's partly because it's their season debuts, but also because they're backend starters.

Then you have to consider that these teams just played an extra-inning game.

High-leverage relievers like Cade Smith (28 pitches) and Andres Muñoz (20 pitches) had heavy workloads, so they may be unavailable for this one.

I know that T-Mobile Park is one of the most pitcher-friendly environments in baseball, but 7.5 runs feels too low considering the probable starters and the taxed bullpens. For context, this number was 7.5 with an ace like Bryan Woo on the mound last night.

Feels like this should be listed at 8.5. With that in mind, we'll take a shot on the over here.

Pick: Guardians/Mariners Over 7.5 (-112, DraftKings)

Playbook

How To Watch Guardians vs Mariners on Sunday Night Baseball

Where: Peacock

When: Sunday, March 29, 7:20 p.m. ET


Guardians vs Mariners Weather


Get the latest coverage on MLB Weather.
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Frank AmmiranteVerified Action Expert

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