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Cardinals vs Nationals Prediction, Pick, MLB Odds for Wednesday, April 8

Cardinals vs Nationals Prediction, Pick, MLB Odds for Wednesday, April 8 article feature image
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Photo Credit: Jeff Curry-Imagn Images
Pictured: Michael McGreevy

The Washington Nationals host the St. Louis Cardinals on April 8, 2026. First pitch from Nationals Park is scheduled for 4:05 p.m. EDT. The game will be broadcast on NATS.

The Cardinals are favored by -120 on the moneyline and by -1.5 on the run line. The Nationals are -100 on the moneyline and +1.5 on the run line. The total is set at 8.5 runs.

Find my MLB picks and Cardinals vs Nationals prediction below, as well as probable pitchers, weather report, and more.


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Cardinals vs Nationals Prediction

  • Cardinals vs Nationals Pick: Michael McGreevy Under 3.5 Strikeouts

My Cardinals vs Nationals best bet is under 3.5 strikeouts for Michael McGreevy tonight. Make sure to find the best odds by checking our live MLB odds page.


Cardinals vs Nationals Odds

Cardinals Logo
April 8, 2026
4:05 p.m. EDT
NATS
Nationals Logo
Cardinals Odds
SpreadTotalMoneyline
-1.5
-160
8.5
-103o / -117u
-120
Nationals Odds
SpreadTotalMoneyline
+1.5
+135
8.5
-103o / -117u
-100
Odds via bet365. Get up-to-the-minute MLB odds here.
bet365 Logo
  • Cardinals vs Nationals spread: Cardinals -1.5 (+135), Nationals +1.5 (-160)
  • Cardinals vs Nationals over/under: 8.5 (-103o / -117u)
  • Cardinals vs Nationals moneyline: Cardinals -120, Nationals -100

Cardinals vs Nationals Projected Starting Pitchers

Michael McGreevyStatMiles Mikolas
6-5W-L4-7
0.3fWAR (FanGraphs)-0.4
2.53 / 7.75ERA /xERA14.46 / 7.80
3.25 / 4.29FIP / xFIP9.69 / 5.59
0.84WHIP2.25
17.1K-BB%8
30GB%31.6
76Stuff+89
111Location+120

Cardinals vs Nationals Preview

Action PRO projects Cardinals starter Michael McGreevy for 2.92 strikeouts in his matchup against the Nationals tonight, giving us a strong 18.9% edge against the market compared to his current prop line of 3.5.

McGreevy has averaged around nine strikeouts per nine innings this season, showing he has the ability to generate swings and misses when he’s in rhythm.

However, he has yet to stay under this line through his first two outings, which is more a function of workload and opportunity than pure dominance. In both starts, he was able to pitch deep enough into games to accumulate strikeouts, something that may not hold in this matchup.

The key question here is whether he will have the same leash tonight. If his outing is shorter or he faces a more contact-oriented Nationals lineup, the path to four strikeouts becomes much thinner.

You can fade him here on his strikeouts prop, with value on Michael McGreevy Under 3.5 Ks.

Pick: Michael McGreevy Under 3.5 Strikeouts

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Cardinals vs Nationals Weather


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