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Brewers vs Red Sox Prediction, Pick, MLB Odds for Monday, April 6

Brewers vs Red Sox Prediction, Pick, MLB Odds for Monday, April 6 article feature image
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Photo Credit: Michael McLoone-Imagn Images
Pictured: Brandon Woodruff delivers a pitch

The Boston Red Sox host the Milwaukee Brewers on April 6, 2026. First pitch from Fenway Park is scheduled for 6:45 p.m. EDT. The game will be broadcast on NESN.

The Brewers are favored by -115 on the moneyline and by -1.5 on the run line. The Red Sox are -105 on the moneyline and +1.5 on the run line. The total is set at 8 runs.

Find my MLB picks and Brewers vs Red Sox prediction below, as well as probable pitchers, weather report, and more.


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Brewers vs Red Sox Prediction

  • Brewers vs Red Sox Pick: Brandon Woodruff Under 6.5 Strikeouts

My Brewers vs Red Sox best bet is Brandon Woodruff under 6.5 strikeouts. Make sure to find the best odds by checking our live MLB odds page.


Brewers vs Red Sox Odds

Brewers Logo
April 6, 2026
6:45 p.m. EDT
NESN
Red Sox Logo
Brewers Odds
SpreadTotalMoneyline
-1.5
-173
8
-110o / -110u
-115
Red Sox Odds
SpreadTotalMoneyline
+1.5
+145
8
-110o / -110u
-105
Odds via DraftKings. Get up-to-the-minute MLB odds here.
DraftKings Logo
  • Brewers vs Red Sox spread: Brewers -1.5 (+145), Red Sox +1.5 (-173)
  • Brewers vs Red Sox over/under: 8 (-110o / -110u)
  • Brewers vs Red Sox moneyline: Brewers -115, Red Sox -105

Brewers vs Red Sox Projected Starting Pitchers

Brandon WoodruffStatBrayan Bello
7-2W-L2-7
0fWAR (FanGraphs)-0.1
3.60 / 3.48ERA /xERA9.64 / 11.74
6 / 3.01FIP / xFIP7.06 / 5.75
0.80WHIP2.36
31.6K-BB%-4
15.4GB%50
98Stuff+97
98Location+102

Brewers vs Red Sox Preview

The Brewers and Red Sox open a new series on Monday, with Milwaukee off to a strong 7-2 start while Boston looks to rebound from a slow 2-7 stretch.

Brayan Bello gets the ball for the Red Sox in his second start of the season after a rough debut. The right-hander allowed five earned runs over 4 2/3 innings against Houston and enters with a 9.64 ERA, along with more walks than strikeouts through his first outing.

On the other side, Brandon Woodruff will make his second start of the year for Milwaukee after a solid showing against Tampa Bay. The right-hander allowed two earned runs over five innings and enters with a 3.60 ERA while holding opponents to a .211 average and generating strikeouts at a strong rate.

At the plate, Milwaukee had one of the best contact profiles in baseball last season, finishing with a .258 batting average, while Boston paired solid power with a .254 average and a .421 slugging percentage. However, both lineups enter this matchup still searching for consistency early in the season.


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Brewers vs Red Sox Picks

There may be some value on Brandon Woodruff’s strikeouts prop. THE BAT X projects him for 5.24 strikeouts, while the market is implying closer to 6.16.

The model gives him a 73% chance to stay under 7 strikeouts, creating a clear edge on the under.

If you can find this line at -135 or better, there’s strong value here, and it remains playable down to -175.

Pick: Brandon Woodruff Under 6.5 Strikeouts

Playbook

Brewers vs Red Sox Weather


Get the latest coverage on MLB Weather.
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