The Boston Red Sox host the Athletics on September 16, 2025. First pitch from Fenway Park is scheduled for 6:45 p.m. EDT; the game will be broadcast on NBCS-CA.
Find my MLB betting preview and Athletics vs Red Sox prediction below, as well as probable pitchers, betting trends, injury reports and more.
Our Athletics vs Red Sox Prediction
- Athletics vs Red Sox pick: Under 8.5
Our Athletics vs Red Sox best bet is on the under total runs. Make sure to find the best odds by checking our live MLB odds page.
Athletics vs Red Sox Odds
| Athletics Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -155 | 8.5 -110o / -110u | +135 |
| Red Sox Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +130 | 8.5 -110o / -110u | -160 |
Athletics vs Red Sox Projected Starting Pitchers
| LHP Jeffrey Springs (ATH) | Stat | LHP Connelly Early (BOS) |
|---|---|---|
| 10-11 | W-L | 1-0 |
| 1.5 | fWAR (FanGraphs) | 0.4 |
| 4.28/4.31 | ERA /xERA | 0.00/2.28 |
| 4.73/4.56 | FIP / xFIP | -0.65/-0.04 |
| 1.20 | WHIP | 1.20 |
| 12.3% | K-BB% | 47.6% |
| 31.8% | GB% | 55.6% |
| 94 | Stuff+ | 101 |
| 99 | Location+ | 111 |
Athletics vs Red Sox Prediction, Betting Analysis
The Boston Red Sox enter Game 1 of this series as a -160 favorite on the moneyline, while the Athletics sit as +135 underdogs. Oddsmakers have set the total at 8.5 runs.
These clubs just met last week, when Boston took the first two games convincingly (7-0 and 6-0), before the Athletics salvaged the finale with a tight 5-4 win. Now back at Fenway, the Red Sox look to strengthen their hold on the AL Wild Card race.
On the mound, Jeffrey Springs gets the ball for road team, while Boston counters with Connelly Early. Early dominated the A’s in his first big-league start last week, tossing a gem in a 6-0 shutout. The 23-year-old lefty will look to replicate that success in his Fenway debut.
This matchup sets up perfectly for Evan Abrams’ “Public Fades Humidity = Unders” system. The conditions in Boston line up: moderate temperatures, humidity in the 45–95% range, and neutral wind patterns. While public perception leans toward humidity fueling offense, data shows the opposite effect—scoring is actually suppressed in these spots.
Pick: Under 8.5 (-110, bet365)
