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Diamondbacks vs Dodgers Prediction, Pick, MLB Odds for Friday, March 27

Diamondbacks vs Dodgers Prediction, Pick, MLB Odds for Friday, March 27 article feature image
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Kirby Lee-Imagn Images. Pictured: Dodgers slugger Shohei Ohtani

The Los Angeles Dodgers host the Arizona Diamondbacks on March 27, 2026. First pitch from Dodger Stadium is scheduled for 10:10 p.m. ET. The game will be broadcast on ARID.

The Dodgers are favored by -259 on the moneyline and by -1.5 on the run line. The Diamondbacks are +209 on the moneyline and +1.5 on the run line. The total is set at 8.5 runs.

Find my MLB picks and Diamondbacks vs Dodgers prediction below, as well as probable pitchers, weather report, and more.


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Diamondbacks vs Dodgers Prediction

  • Diamondbacks vs Dodgers Pick: Diamondbacks ML (+209)

My Diamondbacks vs Dodgers best bet is on Arizona to win outright. Make sure to find the best odds by checking our live MLB odds page.


Diamondbacks vs Dodgers Odds

Diamondbacks Logo
Friday, Mar 27
10:10 p.m. ET
ARID
Dodgers Logo
Diamondbacks Odds
SpreadTotalMoneyline
+1.5
+104
8.5
-115o / -105u
+209
Dodgers Odds
SpreadTotalMoneyline
-1.5
-126
8.5
-115o / -105u
-259
Odds via DraftKings. Get up-to-the-minute MLB odds here.
DraftKings Logo
  • Diamondbacks vs Dodgers spread: Diamondbacks +1.5 (+104), Dodgers -1.5 (-126)
  • Diamondbacks vs Dodgers over/under: 8.5 (-115o / -105u)
  • Diamondbacks vs Dodgers moneyline: Diamondbacks +209, Dodgers -259

Diamondbacks vs Dodgers Projected Starting Pitchers

RHP Ryne Nelson (ARI)2025 StatsRHP Emmet Sheehan (LAD)
7-3W-L6-3
2.0fWAR (FanGraphs)2.1
3.39 / 3.93ERA / xERA2.82 / 3.00
3.73 / 4.05FIP / xFIP2.93 / 3.37
1.07WHIP0.97
14.7K-BB%23.0
39.9GB%33.1
106Stuff+101
101Location+107

Diamondbacks vs Dodgers Betting Preview

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Arizona Diamondbacks Betting Preview

The Diamondbacks are coming off an 8-2 loss in the first game of this series. Zac Gallen struggled against this stacked Dodgers offense, allowing four earned runs in four innings, while reliever Taylor Clarke was rocked for another four earned runs in a third of an inning.

The good news for Arizona is they didn’t use any of their high-leverage relievers in the first game, including veteran Paul Sewald, who is expected to be the team’s closer after a strong spring.

The D-Backs are sending out righty Ryne Nelson, who struck out seven Rangers in five scoreless innings in his final spring start. It was an impressive preseason overall for Nelson, as he had a 35.4% strikeout rate in 17 innings.

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Los Angeles Dodgers Betting Preview

The Dodgers got a strong outing from Yoshinobu Yamamoto in the opener. He went six innings, allowing two earned runs with six strikeouts.

We haven’t yet seen stud closer Edwin Diaz, so he’s completely fresh for this game.

Emmet Sheehan, who is a popular breakout pick, takes the mound for the Dodgers tonight. However, he’s coming off a disappointing spring, where he had some control problems, issuing six walks in only 10 and 2/3 innings.

With that in mind, we could have some value in this game, since the Dodgers are always going to be heavy favorites with their stacked roster.

It may be a spot where we can pick on them.


Diamondbacks vs Dodgers Pick, Betting Analysis

Given what we saw in the second half (3.09 ERA) and how dominant he’s looked in spring, you can make a legitimate case that Ryne Nelson is the best pitcher on the D-Backs right now, especially with Zac Gallen in decline.

While the Diamondbacks aren’t world-beaters by any means, this is still a team that should win 80+ games.

There are some good bats in this lineup, led by superstar Corbin Carroll and veteran Ketel Marte. To that end, it’s not a bad idea to see if they can pull off the upset with their best pitcher on the mound.

With Emmet Sheehan potentially getting off to a slow start this season on the heels of a disappointing spring, coupled with a D-Backs bullpen that still hasn’t used their high-leverage relievers, Arizona looks like a live dog tonight.

Pick: Diamondbacks ML (+209, DraftKings)

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Diamondbacks vs Dodgers Weather


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About the Author
Frank AmmiranteVerified Action Expert

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