Pirates vs. Cardinals Odds & Betting Predictions - May 20, 2026

Pirates at Cardinals

11:45 pm • CARD

Pittsburgh Pirates

2

2 - 0

St. Louis Cardinals

0

MatchupOpenSpreadTotalMoneyline
Pirates 24-24	+1.5	-1.5+164	o7.5-111	-103
Cardinals 28-19	u7.5	+1.5-196	u7.5-110	-117

location pin

Wednesday 11:45 p.m.

May 20, 2026

Busch StadiumSt. Louis

M.McGreevy u17.5 Outs+100

1u

STL -115

1.15u

B.Lowe o1.5 Hits + Runs + RBIs-105

1.05u

STL -120

1.2u

Pirates vs Cardinals: 2 PRO Systems Back This Pick
Action Network Staff•
May 20, 2026 UTC

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MLB Public Betting

Cardinals are 4-1 in their last 5 games.
Cardinals are 3-2 in their last 5 games against the spread
Cardinals are 15-8 in their road games against the spread
The totals have gone OVER in 2 of Cardinals' last 5 games
The totals have gone OVER in 12 of Cardinals' 24 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Cardinals	30-17	15-9	15-8	3-2	27-15
Pirates	25-23	13-13	12-10	15-12	9-11

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Cardinals	21-23-3	12-11-1	9-12-2	2-3	19-20-3
Pirates	26-21-1	16-10	10-11-1	16-11	9-10-1

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Cardinals	28-19	13-11	15-8	3-2	25-17
Pirates	24-24	13-13	11-11	16-11	7-13

date	opponent	score	spread	over/under	moneyline
May 19th	PIT	W 9-6	+1.5 W	O 8	STL -113
May 17th	KC	L 0-2	+1.5 L	U 9.5	KC -120
May 16th	KC	W 4-2	-1.5 W	U 9	STL -112
May 16th	KC	W 5-4	+1.5 W	O 8.5	STL -108
May 14th	@ATH	W 5-4	-1.5 L	U 9.5	STL +101

Jared Jones
SP
Jones is out with elbow
Out

Lars Nootbaar
LF
Nootbaar is out with heel
Out

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PITCHER		PC	IP	K	ER
RC.Mlodzinski, P		78	4	1	0

HITTERS	H-AB	R	HR	RBI
1N.Gonzales, 3B	1-3	0	0	0
2B.Lowe, 2B	1-3	0	0	0
3B.Reynolds, LF	0-2	0	0	0
4O.Cruz, DH	0-2	0	0	0
5S.Horwitz, 1B	1-2	1	1	1
6K.Griffin, SS	2-2	1	0	0
7E.Rodriguez, C	0-1	0	0	0
8J.Garcia, CF	1-2	0	0	1
9J.Mangum, RF	1-2	0	0	0

PITCHER		PC	IP	K	ER
RM.McGreevy, P		73	4	1	2

HITTERS	H-AB	R	HR	RBI
1J.Wetherholt, 2B	2-2	0	0	0
2I.Herrera, C	0-2	0	0	0
3A.Burleson, 1B	0-1	0	0	0
4J.Walker, RF	0-2	0	0	0
5N.Gorman, DH	0-2	0	0	0
6M.Winn, SS	0-2	0	0	0
7C.Prieto, 3B	0-1	0	0	0
8N.Church, LF	1-1	0	0	0
9V.Scott, CF	0-1	0	0	0

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MatchupOverUnder
Pirates 24-24	N/A	N/A
Cardinals 28-19	N/A	N/A