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Mariners vs. Astros Odds & Betting Predictions - September 20, 2025

Mariners at Astros

12:10 am • SCHN

Seattle Mariners

6-6
4
4 - 0

Houston Astros

0-0
0
Starting Pitchers
pitcherteameraw-l
Hunter Brown logoH.BrownHouston Astros logo2.4312-9
Bryan Woo logoB.WooSeattle Mariners logo2.9415-7

Mariners at Astros Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Mariners
6-6
-1.5
-1.5+156
o7.5-102
-108
Astros
0-0
u7.5
+1.5-189
u7.5-120
-111
location pinSaturday 12:10 a.m.
September 20, 2025
Daikin ParkHouston
Mariners vs. Astros Expert Picks
Wags Wins
Wags Wins
Last 30d: 236-203-1 (+29.0u)
HOU -105
1.5u
Payoff Pitch Podcast
Payoff Pitch Podcast
Last 30d: 98-120-2 (+30.9u)
B.Woo u6.5 Ks-140
1u
@cowhitchurch https://myaction.app/7E4QiBJkNWb
Brandon Kravitz
Brandon Kravitz
Last 30d: 65-75-1 (-0.1u)
Under 7+100
1u
Moneyline Hacks
Moneyline Hacks
Last 30d: 106-123-1 (+30.0u)
Under 7.5-121
0.83u
🚨Free analysis & VIP Picks can be found on our Discord. Link: https://discord.gg/A8v49URQaG 🎙️Fade the Noise PODCAST - Subscribe!✅ https://www.youtube.com/@FadetheNoise 🔥60% OFF VIP!! ⬇️⬇️ (COPY & PASTE LINK): https://dubclub.win/r/p/pri-r744p/?checkout=1&coupon=ValueHacks60
Sean Zerillo
Sean Zerillo
Last 30d: 103-113-5 (+5.2u)
SEA +100
0.5u
Bet to -108

Mariners vs. Astros Previews & Analysis

  • Mariners vs Astros: K's Prop Bet for Tonight article feature image

    Mariners vs Astros: K's Prop Bet for Tonight

    Collin Whitchurch•
    Sep 19, 2025 UTC
  • 3 FIRE Home Run Picks for Friday! article feature image

    3 FIRE Home Run Picks for Friday!

    •
    Sep 19, 2025 UTC
See more MLB Coverage Right Arrow

Prop Odds Comparison

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Line Movement Tracker

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Mariners vs. Astros Public Betting Percentages

Away Logo

Mariners

Public

Home Logo

Astros

80%

Bets%

20%

Money%

MLB Public Betting Right Arrow

Betting Trends

  • Astros are 3-2 in their last 5 games.
  • Astros are 3-2 in their last 5 games against the spread
  • Astros are 45-36 in their road games against the spread
  • The totals have gone OVER in 1 of Astros' last 5 games
  • The totals have gone OVER in 36 of Astros' 81 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Astros		82-8037-4445-3643-6039-18
Mariners		69-9336-4533-4844-6924-22

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Astros		72-83-736-43-236-40-545-56-225-27-5
Mariners		88-68-641-35-547-33-158-49-628-18

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Astros		87-7546-3541-4056-4731-26
Mariners		90-7251-3039-4266-4722-24

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 18thTEXW 5-2+1.5 WU 7.5HOU +122
Sep 17thTEXW 6-5+1.5 WO 7.5HOU +100
Sep 16thTEXW 6-3-1.5 WO 8.5HOU -132
Sep 14th@ATLL 3-8-1.5 LO 9ATL -137
Sep 13th@ATLW 6-2-1.5 WU 8.5HOU -139

Mariners vs. Astros Injury Updates

Mariners Injuries

    Astros Injuries

    • Pedro Leon
      RF

      Leon is out with knee

      Out

    • Hayden Wesneski
      RP

      Wesneski is out with elbow

      Out

    See more MLB Injuries Right Arrow
    Mariners vs. Astros Box Score
    Mariners Player Stats
    Projected
    PITCHERPCIPKER
    Bryan Woo logoRB.Woo, P67570
    Eduard Bazardo logoRE.Bazardo, P25220
    Matt Brash logoRM.Brash, P18100
    Andres Munoz logoRA.Munoz, P16120
    HITTERSH-ABRHRRBI
    Randy Arozarena logo1R.Arozarena, LF0-5000
    Cal Raleigh logo2C.Raleigh, C0-2000
    Julio Rodriguez logo3J.Rodriguez, CF1-4111
    Josh Naylor logo4J.Naylor, 1B2-4111
    Jorge Polanco logo5J.Polanco, 2B0-4000
    Eugenio Suarez logo6E.Suarez, 3B1-4111
    Dominic Canzone logo7D.Canzone, DH1-4000
    Victor Robles logo8V.Robles, RF1-3111
    J.P. Crawford logo9J.Crawford, SS3-4000
    Astros Player Stats
    Projected
    PITCHERPCIPKER
    Hunter Brown logoRH.Brown, P99692
    Enyel De Los Santos logoRE.De Los Santos, P17101
    Craig Kimbrel logoRC.Kimbrel, P17101
    Nick Hernandez logoRN.Hernandez, P18110
    HITTERSH-ABRHRRBI
    Jeremy Pena logo1J.Pena, SS0-4000
    Carlos Correa logo2C.Correa, 3B1-4000
    Isaac Paredes logo3I.Paredes, DH1-3000
    Jose Altuve logo4J.Altuve, 2B0-4000
    Zach Cole logo5Z.Cole, RF0-4000
    Christian Walker logo6C.Walker, 1B0-3000
    Yainer Diaz logo7Y.Diaz, C0-3000
    Jesus Sanchez logo8J.Sanchez, LF0-3000
    Jake Meyers logo9J.Meyers, CF1-3000

    Mariners vs. Astros Odds Comparison

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    Mariners at Astros Team Totals

    MatchupOverUnder
    Mariners
    6-6
    o3.5-121
    u3.5-107
    Astros
    0-0
    o3.5-106
    u3.5-122