Guardians vs. Twins Odds & Betting Predictions - May 21, 2025

Guardians at Twins

7:55 pm • MLB Network
5 - 1
Starting Pitchers
pitcherteameraw-l
Chris Paddack logoC.PaddackMinnesota Twins logo3.982-4
Gavin Williams logoG.WilliamsCleveland Guardians logo3.944-2

Guardians at Twins Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Guardians
29-22
+1.5
-1.5+168
o7.5+100
+110
Twins
29-22
u7
+1.5-205
u7.5-119
-130
location pinWednesday 7:55 p.m.
May 21, 2025
Target FieldMinneapolis
Guardians vs. Twins Expert Picks
Top Shelf Action 🥃
Top Shelf Action 🥃
Last 30d: 194-314-8 (+10.5u)
Under 7.5-115
1u
*Winning teams with wind help* Overall: 833-561-74,60% (ROI:15%) Season:7-3-1,70% (ROI:32%)
Moneyline Hacks
Moneyline Hacks
Last 30d: 109-72-2 (+64.5u)
Under 7.5-116
0.86u
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Guardians vs. Twins Previews & Analysis

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Prop Odds Comparison

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Line Movement Tracker

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Guardians vs. Twins Public Betting Percentages

Away Logo

Guardians

Public

25%

Bets%

75%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Twins
29-2216-913-1318-1511-7
Guardians
25-2611-1114-159-1016-15

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Twins
17-31-38-16-19-15-211-20-26-11-1
Guardians
22-26-38-13-114-13-211-811-17-3

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Twins
29-2218-711-1520-139-9
Guardians
29-2214-815-1413-616-15

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
May 21stCLEW 6-5-1.5 LU 11.5MIN -154
May 18th@MILL 2-5+1.5 LU 7.5MIL +123
May 17th@MILW 7-0-1.5 WU 7.5MIN -125
May 17th@MILW 3-0-1.5 WU 7.5MIN -120
May 15th@BALW 4-0+1.5 WU 9MIN +112

Guardians vs. Twins Injury Updates

Guardians Injuries

  • Ben Lively
    SP

    Lively is out with elbow

    Out

  • Shane Bieber
    SP

    Bieber is out with elbow

    Out

  • John Means
    SP

    Means is out with elbow

    Out

  • David Fry
    C

    Fry is out with elbow

    Out

Twins Injuries

    Guardians vs. Twins Box Score
    Guardians Player Stats
    Projected
    PITCHERPCIPKER
    Gavin Williams logoRG.Williams, P98661
    Tim Herrin logoLT.Herrin, P20100
    Hunter Gaddis logoRH.Gaddis, P12110
    Emmanuel Clase logoRE.Clase, P15100
    HITTERSH-ABRHRRBI
    Steven Kwan logo1S.Kwan, LF3-5100
    Angel Martinez logo2A.Martinez, CF0-4001
    Jose Ramirez logo3J.Ramirez, 3B3-5101
    Kyle Manzardo logo4K.Manzardo, 1B0-5000
    Carlos Santana logo5C.Santana, DH2-3211
    Daniel Schneemann logo6D.Schneemann, 2B1-3000
    Gabriel Arias logo7G.Arias, SS0-3001
    Nolan Jones logo8N.Jones, RF1-2001
    Jhonkensy Noel logo8J.Noel, PH1-1100
    Jhonkensy Noel logo8J.Noel, RF1-1100
    Austin Hedges logo9A.Hedges, C0-4000
    Twins Player Stats
    Projected
    PITCHERPCIPKER
    Chris Paddack logoRC.Paddack, P915.122
    Louis Varland logoRL.Varland, P140.200
    Griffin Jax logoRG.Jax, P20130
    Cole Sands logoRC.Sands, P20111
    Kody Funderburk logoLK.Funderburk, P11102
    HITTERSH-ABRHRRBI
    Ryan Jeffers logo1R.Jeffers, DH1-3001
    Brooks Lee logo2B.Lee, SS0-3000
    Royce Lewis logo3R.Lewis, 3B0-4000
    Kody Clemens logo4K.Clemens, 2B1-4000
    Jonah Bride logo5J.Bride, 1B0-4000
    Harrison Bader logo6H.Bader, LF1-3000
    Harrison Bader logo6H.Bader, CF1-3000
    Willi Castro logo7W.Castro, RF0-2100
    Willi Castro logo7W.Castro, LF0-2100
    DaShawn Keirsey logo8D.Keirsey, CF0-2000
    Trevor Larnach logo8T.Larnach, PH0-1000
    Trevor Larnach logo8T.Larnach, RF0-1000
    Christian Vazquez logo9C.Vazquez, C0-3000

    Guardians vs. Twins Odds Comparison

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    Guardians at Twins Team Totals

    MatchupOverUnder
    Guardians
    29-22
    o3.5-115
    u3.5-113
    Twins
    29-22
    o3.5-119
    u3.5-109