Guardians vs. Twins Odds & Betting Predictions - May 21, 2025

Guardians at Twins

7:55 pm • MLB Network
5 - 1
Starting Pitchers
pitcherteameraw-l
Christopher Paddack logoC.PaddackMinnesota Twins logo6.322-3
Gavin Williams logoG.WilliamsCleveland Guardians logo3.0612-5

Guardians at Twins Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Guardians
1-2
+1.5
-1.5+168
o7.5+100
+110
Twins
0-0
u7
+1.5-205
u7.5-119
-130
location pinWednesday 7:55 p.m.
May 21, 2025
Target FieldMinneapolis
Guardians vs. Twins Expert Picks
Moneyline Hacks
Moneyline Hacks
Last 30d: 118-136-5 (+22.0u)
Under 7.5-116
0.86u
🚨Free analysis & VIP Picks can be found on our Discord. Link: https://discord.gg/A8v49URQaG Link to VIP (Copy &Paste): https://linktr.ee/moneylinehacks%F0%9F%94%A560% OFF with promo code: Hacks60
Brandon Kravitz
Brandon Kravitz
Last 30d: 47-64-0 (-12.6u)
Under 7.5+100
0.5u

Guardians vs. Twins Previews & Analysis

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Prop Odds Comparison

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Line Movement Tracker

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Guardians vs. Twins Public Betting Percentages

Away Logo

Guardians

Public

25%

Bets%

75%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Twins
78-8437-4441-4036-5140-31
Guardians
86-7639-4247-3433-3651-38

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Twins
73-83-639-39-334-44-342-42-329-39-3
Guardians
69-87-637-41-332-46-334-34-134-50-5

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Twins
70-9238-4332-4941-4628-43
Guardians
88-7445-3643-3844-2543-46

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
May 21stCLEW 6-5-1.5 L--
May 18th@MILL 2-5+1.5 LU 7.5MIL +123
May 17th@MILW 7-0-1.5 WU 7.5MIN -125
May 17th@MILW 3-0-1.5 WU 7.5MIN -120
May 15th@BALW 4-0+1.5 WU 9MIN +112

Guardians vs. Twins Injury Updates

Guardians Injuries

  • Edward Lively
    SP

    Lively is out with elbow

    Out

  • John Means
    SP

    Means is out with elbow

    Out

Twins Injuries

  • Alan Roden
    LF

    Roden is out with thumb

    Out

Guardians vs. Twins Box Score
Guardians Player Stats
Projected
PITCHERPCIPKER
Gavin Williams logoRG.Williams, P98661
Tim Herrin logoLT.Herrin, P20100
Hunter Gaddis logoRH.Gaddis, P12110
Emmanuel Clase logoRE.Clase, P15100
HITTERSH-ABRHRRBI
Steven Kwan logo1S.Kwan, LF3-5100
Angel Martinez logo2A.Martinez, CF0-4001
Jose Ramirez logo3J.Ramirez, 3B3-5101
Kyle Manzardo logo4K.Manzardo, 1B0-5000
Carlos Santana logo5C.Santana, DH2-3211
Daniel Schneemann logo6D.Schneemann, 2B1-3000
Gabriel Arias logo7G.Arias, SS0-3001
Nolan Jones logo8N.Jones, RF1-2001
Jhonkensy Noel logo8J.Noel, PH1-1100
Jhonkensy Noel logo8J.Noel, RF1-1100
Austin Hedges logo9A.Hedges, C0-4000
Twins Player Stats
Projected
PITCHERPCIPKER
Christopher Paddack logoRC.Paddack, P915.122
Louis Varland logoRL.Varland, P140.200
James Jax logoRG.Jax, P20130
Bryson Sands logoRC.Sands, P20111
Kody Funderburk logoLK.Funderburk, P11102
HITTERSH-ABRHRRBI
Ryan Jeffers logo1R.Jeffers, DH1-3001
Brooks Lee logo2B.Lee, SS0-3000
Royce Lewis logo3R.Lewis, 3B0-4000
Kody Clemens logo4K.Clemens, 2B1-4000
Jonah Bride logo5J.Bride, 1B0-4000
Harrison Bader logo6H.Bader, LF1-3000
Harrison Bader logo6H.Bader, CF1-3000
Willi Castro logo7W.Castro, RF0-2100
Willi Castro logo7W.Castro, LF0-2100
DaShawn Keirsey logo8D.Keirsey, CF0-2000
Trevor Larnach logo8T.Larnach, PH0-1000
Trevor Larnach logo8T.Larnach, RF0-1000
Christian Vazquez logo9C.Vazquez, C0-3000

Guardians vs. Twins Odds Comparison

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Guardians at Twins Team Totals

MatchupOverUnder
Guardians
1-2
o3.5-115
u3.5-113
Twins
0-0
o3.5-119
u3.5-109