Guardians vs. Cardinals Odds & Betting Predictions - September 21, 2024
Guardians at Cardinals
11:15 pm • BSGLStarting Pitchers
pitcher | team | era | w-l | |
---|---|---|---|---|
![]() | ![]() | 5.35 | 10-11 | |
![]() | ![]() | 2.72 | 2-2 |
Guardians at Cardinals Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
---|---|---|---|---|
![]() Guardians 2-7 | -1.5 | -1.5+130 | o7.5-112 | -130 |
![]() Cardinals 3-6 | u8 | +1.5-155 | u7.5-107 | +110 |

Busch StadiumSt. Louis
Guardians vs. Cardinals Expert Picks

Player Prop Savant
163d ago
Last 30d: 56-70-3 (-17.6u)
M.Mikolas u3.5 Ks-124
1.24u

JB Bets
163d ago
Last 30d: 1-0-0 (+0.7u)
CLE -130
1u

Sean Zerillo
164d ago
Last 30d: 34-44-1 (-2.5u)
STL +120
0.6u
Bet to +108
PRO Insights

Guardians
CLE Insights
- Featured Insight
Guardians RPs have allowed a SLG of just .326 this season -- best in MLB. Cardinals hitters are slugging just .358 versus relief pitchers this season -- fifth worst in MLB.
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Cardinals
STL Insights
- Featured Insight
Cardinals hitters have a groundball rate of 47% over the last two weeks -- fifth highest in MLB. Opponents have a groundball rate of just 38% against Guardians over the last two weeks -- third lowest in MLB.
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Guardians vs. Cardinals Notes
Keys to the Game
The Guardians are 62-18 (.775) when they've hit 2 or more home runs since the 2023 season -- 5th best in MLB; League Avg: .698.
The Guardians are 12-6 (.667) when tied entering the 8th inning this season -- tied for 3rd best in MLB; League Avg: .500.
Matchup Contrasts
Andres Gimenez has an OPS of just .677 since last season -- fifth worst in MLB-- fourth Percentile. Ryan Helsley has allowed an OPS of just .556 (401 PAs) since last season -- 11th best among qualified RPs-- 94th Percentile.
Today's Starting Pitchers
Matthew Boyd has a strikeout rate of 33% (20 SO in 61 PAs) this month (3 games) -- 14th best in MLB among starting pitchers with at least 6 total IP; League Avg: 23% -- 91st Percentile.
Matthew Boyd has 7 three-pitch strikeouts this month (3 games) -- tied for 2nd most among pitchers in MLB -- 99th Percentile.
Prop Odds Comparison
Line Movement Tracker
Guardians vs. Cardinals Public Betting Percentages
Betting Trends
- Cardinals are 3-2 in their last 5 games.
- Cardinals are 4-1 in their last 5 games against the spread
- Cardinals are 38-43 in their road games against the spread
- The totals have gone OVER in 3 of Cardinals' last 5 games
- The totals have gone OVER in 37 of Cardinals' 81 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Guardians vs. Cardinals Injury Updates

Guardians Injuries
- Shane BieberP
Bieber is out with elbow
Out
- John MeansP
Means is out with elbow
Out
- David FryC
Fry is out with elbow
Out
- Daniel EspinoP
Espino is out with shoulder
Out

Cardinals Injuries
Guardians vs. Cardinals Box Score

PITCHER | PC | IP | K | ER | |
---|---|---|---|---|---|
![]() | 88 | 4 | 6 | 2 | |
![]() | 20 | 1 | 0 | 0 | |
![]() | 15 | 1 | 2 | 0 | |
![]() | 25 | 1 | 0 | 0 | |
![]() | 9 | 1 | 2 | 0 |
HITTERS | H-AB | R | HR | RBI |
---|---|---|---|---|
![]() | 1-5 | 1 | 0 | 0 |
![]() | 0-3 | 0 | 0 | 0 |
![]() | 1-2 | 1 | 0 | 0 |
![]() | 1-2 | 1 | 0 | 0 |
![]() | 2-4 | 1 | 1 | 3 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 1-3 | 1 | 0 | 0 |
![]() | 1-3 | 1 | 0 | 0 |
![]() | 3-4 | 0 | 0 | 1 |
![]() | 0-2 | 0 | 0 | 0 |
![]() | 1-1 | 0 | 0 | 0 |
![]() | 1-1 | 0 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |
![]() | 1-4 | 1 | 1 | 1 |
![]() | 0-4 | 0 | 0 | 0 |

PITCHER | PC | IP | K | ER | |
---|---|---|---|---|---|
![]() | 81 | 6 | 4 | 1 | |
![]() | 17 | 1 | 1 | 0 | |
![]() | 16 | 0.1 | 0 | 4 | |
![]() | 10 | 0.2 | 1 | 0 | |
![]() | 12 | 1 | 3 | 0 |
HITTERS | H-AB | R | HR | RBI |
---|---|---|---|---|
![]() | 1-4 | 1 | 0 | 0 |
![]() | 1-3 | 0 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |
![]() | 0-1 | 0 | 0 | 0 |
![]() | 1-4 | 1 | 0 | 0 |
![]() | 1-3 | 1 | 0 | 0 |
![]() | 2-3 | 2 | 1 | 3 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 1-3 | 1 | 1 | 2 |
![]() | 0-0 | 0 | 0 | 0 |
![]() | 0-4 | 0 | 0 | 0 |
![]() | 1-3 | 0 | 0 | 0 |
Guardians vs. Cardinals Odds Comparison
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Guardians at Cardinals Team Totals
MatchupOverUnder | ||
---|---|---|
![]() Guardians 2-7 | o3.5-150 | u3.5+115 |
![]() Cardinals 3-6 | o3.5-105 | u3.5-125 |