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Giants vs. Diamondbacks Odds & Betting Predictions - September 17, 2025

Giants at Diamondbacks

1:40 am • ARID
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San Francisco Giants

75-75
@

Arizona Diamondbacks

76-75
Starting Pitchers
pitcherteameraw-l
Eduardo Rodriguez logoE.RodriguezArizona Diamondbacks logo4.988-8

Giants at Diamondbacks Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Giants
75-75
-1.5
+1.5-187
o9-115
+108
Diamondbacks
76-75
u9
-1.5+158
u9-105
-130
location pinWednesday 1:40 a.m.
September 17, 2025
Chase FieldPhoenix
thermometer image97°Fahrenheit
rain image0%Rain
wind image5Wind
Giants vs. Diamondbacks Expert Picks
Lines at Lunch
Lines at Lunch
Last 30d: 90-85-3 (+0.6u)
SF +110
0.91u
Ryan Sura
Ryan Sura
Last 30d: 68-74-3 (-5.9u)
SF +110
1u

Prop Odds Comparison

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No props found

Line Movement Tracker

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Giants vs. Diamondbacks Public Betting Percentages

Away Logo

Giants

Public

Home Logo

Diamondbacks

25%

Bets%

75%

Money%

MLB Public Betting Right Arrow

Betting Trends

  • Diamondbacks are 4-1 in their last 5 games.
  • Diamondbacks are 5-0 in their last 5 games against the spread
  • Diamondbacks are 42-35 in their road games against the spread
  • The totals have gone OVER in 2 of Diamondbacks' last 5 games
  • The totals have gone OVER in 35 of Diamondbacks' 73 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Diamondbacks		78-7236-3742-3535-4942-23
Giants		69-8132-4337-3833-5435-26

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Diamondbacks		74-70-635-33-539-37-141-38-533-31-1
Giants		70-74-632-42-138-32-533-53-135-21-5

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Diamondbacks		76-7539-3437-4043-4132-33
Giants		75-7538-3737-3846-4128-33

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 16thSFW 8-1-1.5 WU 9ARI -132
Sep 14th@MINW 6-4+1.5 WO 9.5ARI +104
Sep 13th@MINW 5-2+1.5 WU 8.5ARI +114
Sep 13th@MINL 8-9+1.5 WO 8.5MIN +120
Sep 10th@SFW 5-3+1.5 WU 9ARI +110

Giants vs. Diamondbacks Injury Updates

Giants Injuries

  • Tom Murphy
    C

    Murphy is out with back

    Out

  • JT Brubaker
    RP

    Brubaker is out with ribs

    Out

Diamondbacks Injuries

  • John Curtiss
    RP

    Curtiss is out with elbow

    Out

See more MLB Injuries Right Arrow
Giants vs. Diamondbacks Starting Lineups
Giants Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Tristan Beck logoRT.Beck, P1-04.881.1046.75
HITTERSAVGOBPSLGHR
Heliot Ramos logo1H.Ramos, LF.261.334.39417
Rafael Devers logo2R.Devers, 1B.272.401.50415
Willy Adames logo3W.Adames, SS.230.318.42728
Matt Chapman logo4M.Chapman, 3B.239.350.44921
Wilmer Flores logo5W.Flores, DH.240.308.37615
Casey Schmitt logo6C.Schmitt, 2B.240.308.40611
Jerar Encarnacion logo7J.Encarnacion, RF.171.171.4002
Jung Hoo Lee logo8J.Lee, CF.264.328.4098
Patrick Bailey logo9P.Bailey, C.218.275.3246
Diamondbacks Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Eduardo Rodriguez logoLE.Rodriguez, P8-84.981.5518.52
HITTERSAVGOBPSLGHR
Geraldo Perdomo logo1G.Perdomo, SS.290.391.46219
Ketel Marte logo2K.Marte, 2B.277.376.50125
Corbin Carroll logo3C.Carroll, RF.255.337.54230
Gabriel Moreno logo4G.Moreno, C.289.347.4569
Adrian Del Castillo logo5A.Del Castillo, DH.236.274.3492
Blaze Alexander logo6B.Alexander, 3B.239.329.4117
Alek Thomas logo7A.Thomas, CF.249.288.3729
Tim Tawa logo8T.Tawa, 1B.215.277.3666
Jake McCarthy logo9J.McCarthy, LF.208.257.3373

Giants vs. Diamondbacks Odds Comparison

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Giants at Diamondbacks Team Totals

MatchupOverUnder
Giants
75-75
N/A
N/A
Diamondbacks
76-75
N/A
N/A