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Cubs vs. Athletics Odds & Betting Predictions - March 21, 2026

Cubs at Athletics

1:10 am • MARQ

Chicago Cubs

9-9
2
2 - 6

Athletics

10-8
6
Starting Pitchers
pitcherteameraw-l
Luis Severino logoL.SeverinoAthletics logo1.291-0
Jameson Taillon logoJ.TaillonChicago Cubs logo17.550-4

Cubs at Athletics Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Cubs
9-9
N/A
N/A
N/A
Athletics
10-8
N/A
N/A
N/A
location pinSaturday 1:10 a.m.
March 21, 2026
HoHoKam ParkMesa

Prop Odds Comparison

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Line Movement Tracker

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Cubs vs. Athletics Public Betting Percentages

Away Logo

Cubs

Public

Home Logo

Athletics

50%

Bets%

50%

Money%

MLB Public Betting Right Arrow

Betting Trends

  • Athletics are 4-1 in their last 5 games.
  • Athletics are 4-1 in their last 5 games against the spread
  • Athletics are 8-4 in their road games against the spread
  • The totals have gone OVER in 3 of Athletics' last 5 games
  • The totals have gone OVER in 5 of Athletics' 6 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Athletics		12-64-28-41-110-5
Cubs		7-113-64-53-84-3

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Athletics		7-10-15-12-9-12-04-10-1
Cubs		11-75-46-36-55-2

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Athletics		10-84-26-61-18-7
Cubs		9-94-55-45-64-3

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Mar 20thSEAL 4-6-1.5 LU 12.5SEA -142
Mar 17th@CWSL 4-6+1.5 LU 12.5CWS +100
Mar 16thLAAW 3-0-1.5 WU 11.5ATH -160
Mar 15th@CLEL 6-12+1.5 LO 11.5CLE +125
Mar 14thKCW 12-1-1.5 WO 11.5ATH -168

Athletics vs. Cubs Injury Updates

Athletics Injuries

  • Gunnar Hoglund
    SP

    Hoglund is out with back

    Out

Cubs Injuries

  • Tyler Austin
    1B

    Austin is out with knee

    Out

  • Justin Steele
    SP

    Steele is out with elbow

    Out

  • Jordan Wicks
    SP

    Wicks is out with arm

    Out

See more MLB Injuries Right Arrow
Cubs vs. Athletics Box Score
Cubs Player Stats
Projected
PITCHERPCIPKER
Jameson Taillon logoRJ.Taillon, P78463
Javier Assad logoRJ.Assad, P502.131
Zac Leigh logoRZ. Leigh, P50.210
HITTERSH-ABRHRRBI
Michael Busch logo1M.Busch, 1B0-3000
Nico Hoerner logo2N.Hoerner, SS1-3000
Miguel Amaya logo3M.Amaya, C2-3222
Kevin Alcantara logo4K.Alcantara, CF0-3000
Dylan Carlson logo5D.Carlson, LF0-3000
Jonathon Long logo6J. Long, DH0-3000
BJ Murray Jr. logo8B. Murray, 3B1-3000
Scott Kingery logo9S.Kingery, 2B0-4000
Athletics Player Stats
Projected
PITCHERPCIPKER
Luis Severino logoRL.Severino, P79571
Nick Anderson logoRN.Anderson, P17121
Mark Leiter logoRM.Leiter, P11120
Michael Kelly logoRM.Kelly, P34220
HITTERSH-ABRHRRBI
Lawrence Butler logo1L.Butler, RF1-3112
Colby Thomas logo1C.Thomas, RF0-1001
Nick Kurtz logo2N.Kurtz, 1B0-3000
Serven logo2B.Serven, C0-2000
Shea Langeliers logo3S.Langeliers, C1-2111
Tyler Soderstrom logo4T.Soderstrom, LF0-3000
Daniel Bucciero logo4D.Bucciero, 1B0-2000
Brent Rooker logo5B.Rooker, DH2-3000
Devin Taylor logo5D.Taylor, PH0-1000
Devin Taylor logo5D.Taylor, DH0-1000
Jacob Wilson logo6J.Wilson, SS2-3000
Jeff McNeil logo7J.McNeil, CF1-3000
Max Muncy logo8M.Muncy, 3B1-2111
Casey Yamauchi logo8C.Yamauchi, PR0-0100
Casey Yamauchi logo8C.Yamauchi, 3B0-0100
Casey Yamauchi logo8C.Yamauchi, 2B0-0100
Andy Ibanez logo9A.Ibanez, 2B2-3101
Andy Ibanez logo9A.Ibanez, 3B2-3101

Cubs vs. Athletics Odds Comparison

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Cubs at Athletics Team Totals

MatchupOverUnder
Cubs
9-9
N/A
N/A
Athletics
10-8
N/A
N/A