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Cardinals vs. Astros Odds & Betting Predictions - April 18, 2026

Cardinals at Astros

12:10 am • SCHN

St. Louis Cardinals

10-8
@

Houston Astros

8-12
Starting Pitchers
pitcherteameraw-l
Lambert logoP.LambertHouston Astros logo0.000-0
Kyle Leahy logoK.LeahySt. Louis Cardinals logo5.141-2

Cardinals at Astros Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Cardinals
10-8
+1.5
+1.5-185
o9+100
+116
Astros
8-12
u8.5
-1.5+154
u9-119
-140
location pinSaturday 12:10 a.m.
April 18, 2026
Daikin ParkHouston
thermometer image80°Fahrenheit
rain image0%Rain
wind image13Wind
Cardinals vs. Astros Expert Picks
Ryan Minion
Ryan Minion
Last 30d: 212-268-4 (-17.4u)
Y.Alvarez o2 Hits + Runs + RBIs-115
$1.15
Grant Neiffer
Grant Neiffer
Last 30d: 18-96-3 (+2.3u)
J.Walker o0.5 HR+490
0.25u
Payoff Pitch Podcast
Payoff Pitch Podcast
Last 30d: 79-116-8 (-6.5u)
J.Walker o0.5 HR+525
0.25u
@DerekCarty ⭐️ https://myaction.app/avOg33kJp2b
P.Lambert o1.5 BB-130
1u
@cowhitchurch ⭐️⭐️⭐️ https://myaction.app/avOg33kJp2b
RoyalsProps
RoyalsProps
Last 30d: 61-48-5 (+8.6u)
C.Smith o1.5 Hits + Runs + RBIs-107
1.07u
Frank Ammirante
Frank Ammirante
Last 30d: 179-238-13 (-22.1u)
K.Leahy u3.5 Ks+110
0.91u
Y.Alvarez o0.5 HR+350
0.1u
OldSchool0909
Last 30d: 138-141-0 (+15.6u)
STL +120
1u

Cardinals vs. Astros Previews & Analysis

  • Cardinals vs Astros: Whitchurch's Pitcher Prop for Friday article feature image

    Cardinals vs Astros: Whitchurch's Pitcher Prop for Friday

    Collin Whitchurch•
    Apr 17, 2026 UTC
  • Grant's Home Run Bets for Friday article feature image

    Grant's Home Run Bets for Friday

    Grant Neiffer•
    Apr 17, 2026 UTC
  • MLB Best Bets for Friday article feature image

    MLB Best Bets for Friday

    Action Network Staff•
    Apr 17, 2026 UTC
  • Trigger's Triple-A Picks For Friday article feature image

    Trigger's Triple-A Picks For Friday

    Adam Trigger•
    Apr 17, 2026 UTC
See more MLB Coverage Right Arrow

Prop Odds Comparison

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No props found

Line Movement Tracker

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Cardinals vs. Astros Public Betting Percentages

Away Logo

Cardinals

Public

Home Logo

Astros

39%

Bets%

61%

Money%

MLB Public Betting Right Arrow

Betting Trends

  • Astros are 2-3 in their last 5 games.
  • Astros are 1-4 in their last 5 games against the spread
  • Astros are 2-8 in their road games against the spread
  • The totals have gone OVER in 1 of Astros' last 5 games
  • The totals have gone OVER in 6 of Astros' 10 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Astros		8-126-42-84-84-3
Cardinals		10-87-53-31-19-7

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Astros		12-7-16-46-3-16-65-1-1
Cardinals		10-7-17-53-2-11-19-6-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Astros		8-127-31-95-73-4
Cardinals		10-87-53-31-19-7

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Apr 17thCOLL 2-3-1.5 LU 8.5COL -171
Apr 16thCOLW 3-1-1.5 WU 8.5HOU -196
Apr 15thCOLW 7-6-1.5 LO 8.5HOU -186
Apr 13th@SEAL 2-6+1.5 LU 8SEA +149
Apr 12th@SEAL 1-6+1.5 LU 7.5SEA +162

Astros vs. Cardinals Injury Updates

Astros Injuries

  • Zach Dezenzo
    LF

    Dezenzo is out with elbow

    Out

Cardinals Injuries

  • Jose Fermin
    2B

    Jose Fermin has been scratched Tuesday.

    Out

  • Lars Nootbaar
    LF

    Nootbaar is out with heel

    Out

  • Hunter Dobbins
    SP

    Dobbins is out with knee

    Out

See more MLB Injuries Right Arrow
Cardinals vs. Astros Starting Lineups
Cardinals Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Kyle Leahy logoRK.Leahy, P1-25.141.7144.50
HITTERSAVGOBPSLGHR
JJ Wetherholt logo1J.Wetherholt, 2B.227.354.3793
Ivan Herrera logo2I.Herrera, DH.194.386.2901
Alec Burleson logo3A.Burleson, 1B.279.375.4122
Jordan Walker logo4J.Walker, RF.319.373.7108
Nolan Gorman logo5N.Gorman, 3B.208.290.3212
Masyn Winn logo6M.Winn, SS.188.339.2500
Nathan Church logo7N.Church, LF.205.238.3081
Pedro Pages logo8P.Pages, C.206.263.3241
Victor Scott logo9V.Scott, CF.255.294.2770
Astros Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
HITTERSAVGOBPSLGHR
Jose Altuve logo1J.Altuve, 2B.300.417.4712
Yordan Alvarez logo2Y.Alvarez, DH.328.483.7317
Isaac Paredes logo3I.Paredes, 3B.208.344.2830
Carlos Correa logo4C.Correa, SS.277.356.3851
Christian Walker logo5C.Walker, 1B.294.388.5594
Joey Loperfido logo6J.Loperfido, LF.273.349.3640
Cam Smith logo7C.Smith, RF.271.350.4713
Taylor Trammell logo8T.Trammell, CF.250.368.3130
Yainer Diaz logo9Y.Diaz, C.186.222.2541

Cardinals vs. Astros Odds Comparison

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Cardinals at Astros Team Totals

MatchupOverUnder
Cardinals
10-8
N/A
N/A
Astros
8-12
N/A
N/A