Astros vs. Cardinals Odds & Betting Predictions - March 21, 2025

Astros at Cardinals

5:05 pm

Houston Astros

5

5 - 3

St. Louis Cardinals

3

pitcher		team	era	w-l
S.Gray			12.56	0-3
F.Valdez			3.45	2-0

MatchupOpenSpreadTotalMoneyline
Astros 61-47	N/A	N/A	N/A
Cardinals 55-54	N/A	N/A	N/A

location pin

Friday 5:05 p.m.

March 21, 2025

Roger Dean StadiumJupiter

No props found

MLB Public Betting

Cardinals are 2-3 in their last 5 games.
Cardinals are 2-3 in their last 5 games against the spread
Cardinals are 27-27 in their road games against the spread
The totals have gone OVER in 1 of Cardinals' last 5 games
The totals have gone OVER in 29 of Cardinals' 55 last games at home

Against the Spread (ATS) History

	overall	home	away	favorite	underdog
Cardinals	57-52	30-25	27-27	22-30	34-22
Astros	55-53	27-31	28-22	31-45	24-7

Over/Under History

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Cardinals	55-48-6	29-23-3	26-25-3	26-21-5	28-27-1
Astros	45-57-6	24-33-1	21-24-5	35-39-2	9-18-4

Straight-Up (ML) History

	overall	home	away	favorite	underdog
Cardinals	55-54	32-23	23-31	27-25	27-29
Astros	61-47	34-24	27-23	42-34	19-12

date	opponent	score	spread	over/under	moneyline
Mar 19th	WSH	W 7-1	-1.5 W	U 8.5	STL -148
Mar 18th	MIA	W 4-4	-1.5 L	U 8	MIA -165
Mar 17th	@WSH	W 6-2	+1.5 W	U 8	STL +157
Mar 16th	@MIA	L 5-11	-1.5 L	O 9	MIA -132
Mar 15th	TOR	W 9-5	-1.5 W	O 8.5	STL -165

Nolan Gorman
2B
Gorman is out with back
Out

Jake Meyers
CF
Meyers is out with calf
Out
Cristian Javier
SP
Javier is out with elbow
Out
Jeremy Pena
SS
Pena is out with ribs
Out
Luis Garcia
SP
Garcia is out with elbow
Out
Pedro Leon
RF
Leon is out with knee
Out
J.P. France
SP
France is out with shoulder
Out
Hayden Wesneski
RP
Wesneski is out with elbow
Out
Spencer Arrighetti
SP
Arrighetti is out with thumb
Out

See more MLB Injuries

PITCHER		PC	IP	K	ER
LF.Valdez, P		86	5	6	3
RR.Gusto, P		21	1	2	0
LJ.Beeks, P		13	1	1	0
LB.King, P		14	1	1	0
RL.Contreras, P		14	1	2	0

HITTERS	H-AB	R	HR	RBI
1J.Altuve, LF	0-3	0	0	0
1C.Hummel, PH	1-2	0	0	0
1C.Hummel, LF	1-2	0	0	0
2J.Pena, SS	3-3	2	1	1
2Z.Short, SS	0-1	0	0	0
3I.Paredes, 3B	1-3	0	0	1
3L.Guillorme, PH	0-2	0	0	0
3L.Guillorme, 3B	0-2	0	0	0
4Y.Diaz, C	1-3	0	0	0
5C.Smith, RF	0-4	0	0	0
6J.Singleton, DH	1-2	1	0	0
6B.Gamel, PH	0-1	0	0	0
6B.Gamel, DH	0-1	0	0	0
7V.Caratini, 1B	0-3	0	0	0
7L. Castro, 1B	0-1	0	0	0
8B.Rodgers, 2B	1-4	1	0	0
9C.McCormick, CF	1-3	1	1	3
9L. Cerny, CF	1-1	0	0	0

PITCHER		PC	IP	K	ER
RS.Gray, P		80	4.2	5	5
RA. Marrero, P		7	0.1	0	0
RS.Gray, P		80	4.2	5	5
LQ. Mathews, P		62	4	6	0

HITTERS	H-AB	R	HR	RBI
1M.Winn, SS	0-4	0	0	0
1M. Villarroel, SS	0-0	0	0	0
2L.Nootbaar, LF	0-3	0	0	0
2M. Antico, LF	0-1	0	0	0
3W.Contreras, 1B	0-2	0	0	0
3M. Lloyd, 1B	1-1	0	0	0
4B.Donovan, 2B	0-3	0	0	0
4B. Moore, 2B	0-1	0	0	0
5I.Herrera, C	0-2	0	0	0
5G. Collins, C	0-1	0	0	0
6L.Baker, DH	0-2	0	0	0
6C. Rotondo, PR	0-0	0	0	0
7V.Scott, CF	1-2	2	1	1
7D. Moquete, CF	0-1	0	0	0
8C. Prieto, 3B	1-4	0	0	0
9R.Vilade, RF	1-4	1	1	2

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MatchupOverUnder
Astros 61-47	N/A	N/A
Cardinals 55-54	N/A	N/A