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Pittsburgh Penguins vs Calgary Flames Predictions, Pick, Odds, Wednesday, January 21

Pittsburgh Penguins vs Calgary Flames Predictions, Pick, Odds, Wednesday, January 21 article feature image
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Photo Credit: Steven Bisig-Imagn Images, Pictured: Kris Letang

The Pittsburgh Penguins (23-14-11) and Calgary Flames (21-23-5) meet in the NHL tonight. Puck drop is set for 9:30 p.m. EST at Scotiabank Saddledome in Calgary, AB. The game will be broadcast live on ESPN+.

The Penguins are favored by -1.5 on the puck line, with the over/under set at 5.5 (-132o / +110u). The Penguins are a -118 favorite to win outright, while the Flames are -102 to pull off the upset.

Let's get into my Penguins vs. Flames predictions and NHL picks.

Penguins vs. Flames Odds, Pick

Penguins Logo
Wednesday, January 21, 2026
9:30 p.m. EST
ESPN+
Flames Logo
Penguins Odds
SpreadTotalMoneyline
-1.5
+210
5.5
-132o / +110u
-118
Flames Odds
SpreadTotalMoneyline
+1.5
-260
5.5
-132o / +110u
-102
Odds via bet365. Get up-to-the-minute NHL odds here.
bet365 Logo

Penguins vs. Flames Spread: Penguins -1.5 (+210), Flames +1.5 (-260)

Penguins vs. Flames Over/Under: 5.5 (-132o / +110u)

Penguins vs. Flames Moneyline: Penguins -118, Flames -102

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Penguins vs. Flames Preview

This system focuses on situations where a team is at home as an underdog after dropping its last game in that same building by a narrow margin. While it might appear that home ice and recent motivation create value, these spots often expose deeper issues.

A team priced as a dog at home after a recent home defeat usually signals a lack of market trust in their roster, goaltending, or form, and the emotional lift of playing at home does not offset those gaps.

Oddsmakers expect the losing trend to continue, and public bettors often overestimate bounce-back potential, making it more profitable to fade these clubs despite their home setting.


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Penguins vs. Flames Prediction

Best Bet: Penguins Moneyline
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