Maple Leafs vs. Senators Odds & Betting Predictions - September 21, 2025
Maple Leafs at Senators
7:00 pmMaple Leafs at Senators Odds
Spread, Total, Moneyline
| MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
|  Maple Leafs5-5-1 | +1.5 | +1.5+115 | o7.5-113 | -130 | 
|  Senators 6-5-1 | u6.5 | -1.5-135 | u7.5-117 | -102 | 

Canadian Tire CentreOttawa
Prop Odds Comparison
Line Movement Tracker
Maple Leafs vs. Senators Public Betting Percentages
Betting Trends
- Senators are 3-2 in their last 5 games.
- Senators are 1-4 in their last 5 games against the spread
- Senators are 2-3 in their road games against the spread
- The totals have gone OVER in 3 of Senators' last 5 games
- The totals have gone OVER in 4 of Senators' 7 last games at home
Matchup History
Against the Spread (ATS) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
|  | 4-8 | 2-5 | 2-3 | 1-7 | 3-1 | 
|  | 2-9 | 2-6 | 0-3 | 2-8 | 0-1 | 
Over/Under History
| overall | home o/u | away o/u | favorite o/u | underdog o/u | |
|---|---|---|---|---|---|
|  | 9-3 | 4-3 | 5-0 | 6-2 | 3-1 | 
|  | 9-2 | 6-2 | 3-0 | 8-2 | 1-0 | 
Straight-Up (ML) History
| overall | home | away | favorite | underdog | |
|---|---|---|---|---|---|
|  | 6-5 | N/A | N/A | 4-4 | 2-2 | 
|  | 5-5 | N/A | N/A | 5-5 | 0-1 | 
Last 5 Matchups
Maple Leafs vs. Senators Injury Updates

Maple Leafs Injuries
- Christopher TanevDTanev is out with upper body Out 
- Calle JarnkrokCJarnkrok is day-to-day with lower body Day-to-Day 
- Scott LaughtonLWLaughton is out with lower body Out 
- Marshall RifaiDRifai is out with wrist Out 

Senators Injuries
- Brady TkachukLWTkachuk is out with thumb Out 
Team Stats
Maple Leafs vs. Senators Odds Comparison
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Maple Leafs at Senators Team Totals
| MatchupOverUnder | ||
|---|---|---|
|  Maple Leafs5-5-1 | N/A | N/A | 
|  Senators 6-5-1 | N/A | N/A | 
