The New Orleans Saints (5-10) and Tennessee Titans (3-12) will meet in Week 17 of the NFL season on Sunday afternoon. Kickoff is set for 1:00 p.m. ET from Nissan Stadium in Nashville, Tennessee. The game will broadcast live on CBS.
The Saints are 1.5-point favorites over the Titans on the spread (Saints -1.5), with the over/under set at 39.5 total points. New Orleans is a -125 favorite to win outright on the moneyline, while Tennessee is +105 to pull off the upset.
Let's get into my Saints vs Titans predictions and NFL picks for Sunday, December 28.
Saints vs Titans Prediction, Picks
- Saints vs Titans pick: Over 39.5 (-110)
My Titans vs. Saints best bet is the over at 39.5 total points, with the best price currently available at bet365. However, make sure to find the best odds by checking our live NFL odds page.
Saints vs Titans Odds for NFL Week 17
| Saints Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 -110 | 39.5 -110o / -110u | -125 |
| Titans Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -110 | 39.5 -110o / -110u | +105 |
New Orleans Saints vs Tennessee Titans Preview
The Saints have been one of the more interesting teams in the NFL during the latter half of the season.
The development of quarterback Tyler Shough into a viable starter heading into 2026 and beyond has been the headline, but their defense deserves credit for how well it has played in recent weeks.
New Orleans has allowed just 4.4 yards per play to opposing offenses since Week 10 — the best mark in the NFL over that span. However, some context is required.
The Buccaneers' Baker Mayfield is the best quarterback they’ve faced during that stretch, and even he wasn’t at full health or surrounded by his usual supporting cast.
Three of those games came at home against Bryce Young, Kirk Cousins and Brady Cook. Their lone road game in that span came against Tua Tagovailoa, who attempted just 23 passes in a win. One week prior, in Week 9, the Saints surrendered 34 points on the road.
Saints head coach Kellen Moore has consistently brought a high-paced attack to his offenses, and the Saints are no exception despite a rookie quarterback under center.
New Orleans leads the NFL in pace across nearly every category and is coming off a performance against the Jets in which it called pass plays at a season-high 12% above expectation.
With Shough completing 68% of his passes since Week 10, it’s fair to expect Moore to again lean on the passing game, potentially pushing his quarterback toward 40 attempts.
Meanwhile, Cam Ward isn’t necessarily a tier above the quarterbacks New Orleans has faced recently. However, he has been playing better of late, and the game plans from Titans' interim head coach Mike McCoy and offensive coordinator Nick Holz have reflected that improvement.
Ward has thrown multiple touchdown passes in three consecutive games, with the offense scoring 10 times over that span. He’s also coming off his most efficient performance of the season, setting career highs in both completion percentage and yards per attempt last week.
As a result, the coaching staff has opened things up compared to the first three quarters of the season. Tennessee’s offense played at the slowest neutral pace in the league earlier in the year, but over the last month, that pace has climbed to 23rd.
This is particularly relevant against a Saints team that will gladly push the tempo.
Tennessee’s defense has been sound against the run, but it ranks 28th in pass defense success rate. This unit functions as a classic pass-funnel, prioritizing run defense while allowing a high volume of completions through the air.
The Titans rank 29th in yards per attempt allowed (7.9), and opposing quarterbacks have posted a collective 104.4 passer rating against them, the fourth-worst mark in the NFL.
Saints vs Titans Betting Predictions, Analysis
With play volume working in our favor and the confidence of each offensive staff in its quarterback continuing to rise, I’m expecting points to be put on the scoreboard in this matchup.
On what’s forecasted to be a near 70-degree day in Nashville, conditions are ripe for an over.
Three of the last five games involving Tennessee have seen the over cash, with the two unders in that span coming in games where one of the teams failed to reach double-digit points. That shouldn’t be the case for either offense in this spot.
Saints vs Titans Best Bet
- Over 39.5 (-110)
Saints vs Titans Betting Trends
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