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Jaguars vs Colts Predictions, Picks & Odds

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Action Network/Imagn Images: Trevor Lawrence, Philip Rivers.

The Jaguars (11-4) and Colts (8-7) meet today in an NFL Week 17 AFC South clash. Kickoff is set for 1 p.m. ET from Lucas Oil Stadium in Indianapolis, Ind. Jaguars vs Colts will broadcast on FOX.

The Jaguars are 4.5-point favorites on the spread (Jaguars -4.5); the game total is 48.5. Jacksonville is a -230 moneyline favorite; Indianapolis is a +190 underdog.

Let's get into my Jaguars vs Colts predictions.


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Jaguars vs Colts Predictions & Picks

  • Jaguars vs Colts pick: Colts +6.5 (-110)

My Jaguars vs Colts best bet is on Indianapolis to cover the spread. Find the best odds by checking our live NFL odds page.


Jaguars vs Colts Odds, Lines

Jaguars Logo
Sunday, Dec. 28
1 p.m. ET
FOX
Colts Logo
Jaguars Odds
SpreadTotalMoneyline
-4.5
-110
48.5
-110o / -110u
-230
Colts Odds
SpreadTotalMoneyline
+4.5
-110
48.5
-110o / -110u
+190
Odds via bet365. Get up-to-the-minute NFL odds here.
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Jaguars vs Colts Preview Prediction

I was on the wrong side of the Colts last week , and honestly, that was just a bad call.

Nine days is simply too much time to prepare for an opposing defense, and it resulted in the 49ers moving up and down the field every possession against the Colts.

That said, the Colts offense was good enough to win. Philip Rivers and company managed to score 27 points on 312 total yards (5.4 yards per play). However, they never stood a chance with their defense surrendering 41 points on 440 total yards.

The Colts fumbled a kickoff in that game, which is basically seven free points when you can't get any stops. Then there was the sack-fumble that should have been a huge defensive play, but instead turned into a 12-yard gain — and yes, Rivers threw a pick-six, but by that point, the game was already decided.

The Colts defense was incredibly disappointing, though. Last week's effort was brutal. It felt like nobody showed up — and that’s what stood out the most: the lack of emotion.

I know the Colts are really banged up right now, but where was the urgency?

It felt like the only guy who cared, with the season on the line, was their 44-year-old quarterback who was just signed off the couch. Rivers was chirping, getting into it, and honestly I enjoyed that part.

For context, Rivers hasn’t been nearly as bad as the market suggested. His passing yards prop against a terrible 49ers defense was around 160, and he cleared that in the first half. In a small sample, he ranks 23rd in composite of EPA+CPOE among quarterbacks with at least 20 dropbacks.

That’s not great, but it’s also not third-string, unplayable quarterback territory either. By adjusted EPA per play, he would rank 20th. In standard EPA per play, he’s around +0.03, which means he’s still adding points.

For reference, that’s in the range of Jacoby Brissett and Jayden Daniels. Again, not great, but certainly not terrible. Rivers made some good throws on Monday night. It doesn’t always look pretty coming out of his hand, but the accuracy was there.

Now, you’re talking about an important division game for the Colts against the Jaguars, another home spot for them. Rivers isn’t playing at some kind of Daniel Jones breakout level, but competent quarterback play matters — and the Colts defense isn’t going to be as bad as they were on Monday night in every game.

Sometimes you see this kind of performance in non-conference games, where there’s less familiarity between teams and a coach like Kyle Shanahan can run circles around you. This is a totally different situation against the Jaguars.


Jaguars vs Colts Predictions, Against the Spread Pick

This is a divisional game, the second meeting between these teams, and a clear revenge spot for the Colts.

On the season, the Colts are fourth in overall DVOA; the Jaguars are fifth.

This is still a very talented Colts team. Sure, they have injuries, but they can adjust. Rivers can still place the ball accurately, which I was genuinely worried about coming into last week — but I'm feeling more confident now.

This just feels like too many points for a Colts team that has plenty of talent, now in a desperation spot. It’s a second division game at home, catching 6.5 points against a Jaguars team that we like, but one that hasn’t been as strong on the road.

The Jaguars are coming off a huge win against the Broncos, but they were outgained 445 to 346 in that game. Before that, they played the Jets, Colts, Titans, Cardinals and a Chargers team with some serious offensive line issues.

I see a potential letdown spot for the Jaguars here.

The Trevor Lawrence and Liam Coen hype is real, and I'm still in on them, but this might be the peak of the market on the Jaguars and the bottom of the market for the Colts.

The Colts are just one game over .500, coming off a primetime blowout, and everyone thinks they’re done — which is quite different than how we were talking about them not too long ago.

Pick: Colts +6.5 (-110)

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Jaguars vs Colts Betting Trends


Jaguars vs Colts Viewing Info: Channel, Start Time, Streaming

Location:Lucas Oil Stadium in Indianapolis, Ind.
Date:Sunday, Dec. 28
Time:1 p.m. ET
TV / Streaming Options:CBS

For the latest on NFL injuries, be sure to check out our NFL Injury Report page.


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About the Author

Chris Raybon is a senior betting analyst at the Action Network, specializing in NFL, NBA, and fantasy football betting. He hosts The Action Network Podcast, with profitable NFL ATS picks every season, and the Fantasy Flex Podcast, while regularly appearing on NBA TV’s NBA BET and Turner Sports’ The Line. With over 15 years of betting experience, Chris boasts a 57% all-time winning percentage on NFL bets and top-5 finishes in FantasyPros accuracy rankings.

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